(Q90380582)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30031105%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

title

EphBs and ephrin-Bs: Trans-synaptic organizers of synapse development and function (English)

1 reference

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13 April 2020

Nathan T Henderson

1 reference

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13 April 2020

Matthew B Dalva

series ordinal

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13 April 2020

publication date

19 July 2018

1 reference

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Molecular and Cellular Neuroscience

13 April 2020

published in

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13 April 2020

volume

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13 April 2020

page(s)

108-121

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Long-term potentiation of guinea pig mossy fiber responses is not blocked by N-methyl D-aspartate antagonists

13 April 2020

cites work

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12 December 2020

Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity

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12 December 2020

Ligand activation of ELK receptor tyrosine kinase promotes its association with Grb10 and Grb2 in vascular endothelial cells

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12 December 2020

Synaptic activity and the construction of cortical circuits

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12 December 2020

Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes, attachment, and assembly responses

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12 December 2020

Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4

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12 December 2020

Complex formation between EphB2 and Src requires phosphorylation of tyrosine 611 in the EphB2 juxtamembrane region

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12 December 2020

Localization and regulation of MuSK at the neuromuscular junction

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12 December 2020

Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein

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12 December 2020

PDZ proteins bind, cluster, and synaptically colocalize with Eph receptors and their ephrin ligands

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12 December 2020

The carboxyl terminus of B class ephrins constitutes a PDZ domain binding motif

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12 December 2020

EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains

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12 December 2020

A developmental change in NMDA receptor-associated proteins at hippocampal synapses

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12 December 2020

Neuronal plasticity: increasing the gain in pain

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12 December 2020

Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons

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12 December 2020

EphB receptors interact with NMDA receptors and regulate excitatory synapse formation

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12 December 2020

Expression of ephrinB2 identifies a stable genetic difference between arterial and venous vascular smooth muscle as well as endothelial cells, and marks subsets of microvessels at sites of adult neovascularization.

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12 December 2020

Forward signaling mediated by ephrin-B3 prevents contralateral corticospinal axons from recrossing the spinal cord midline

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12 December 2020

Ephrin-B3 is the midline barrier that prevents corticospinal tract axons from recrossing, allowing for unilateral motor control

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12 December 2020

The SH2/SH3 adaptor Grb4 transduces B-ephrin reverse signals

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12 December 2020

Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region

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12 December 2020

EphB/syndecan-2 signaling in dendritic spine morphogenesis

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12 December 2020

Dendritic spines: structure, dynamics and regulation

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12 December 2020

Kinase-independent requirement of EphB2 receptors in hippocampal synaptic plasticity

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12 December 2020

The receptor tyrosine kinase EphB2 regulates NMDA-dependent synaptic function

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12 December 2020

Crystal structure of an Eph receptor-ephrin complex

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12 December 2020

Synaptophysin regulates activity-dependent synapse formation in cultured hippocampal neurons

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12 December 2020

Modulation of NMDA receptor-dependent calcium influx and gene expression through EphB receptors

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12 December 2020

Purification, crystallization and preliminary characterization of an Eph-B2/ephrin-B2 complex

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12 December 2020

AMPA receptor trafficking and synaptic plasticity

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12 December 2020

Trans-synaptic Eph receptor-ephrin signaling in hippocampal mossy fiber LTP

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12 December 2020

EphB receptors regulate dendritic spine development via intersectin, Cdc42 and N-WASP.

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12 December 2020

Alzheimer's disease is a synaptic failure

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12 December 2020

mRNA expression of ephrins and Eph receptor tyrosine kinases in the neonatal and adult mouse central nervous system

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12 December 2020

Eph signaling: a structural view

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12 December 2020

Rapid induction of dendritic spine morphogenesis by trans-synaptic ephrinB-EphB receptor activation of the Rho-GEF kalirin

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12 December 2020

EphB receptors and ephrin-B ligands regulate spinal sensory connectivity and modulate pain processing.

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12 December 2020

Multiple roles of ephrins in morphogenesis, neuronal networking, and brain function.

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12 December 2020

Multiple EphB receptor tyrosine kinases shape dendritic spines in the hippocampus

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12 December 2020

Hippocampal plasticity requires postsynaptic ephrinBs.

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12 December 2020

Ephrin-B1 forward and reverse signaling are required during mouse development

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12 December 2020

A GIT1/PIX/Rac/PAK signaling module regulates spine morphogenesis and synapse formation through MLC

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12 December 2020

Mosaic analysis with double markers in mice.

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12 December 2020

Induction of ephrin-B1 and EphB receptors during denervation-induced plasticity in the adult mouse hippocampus

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12 December 2020

GRIP1 controls dendrite morphogenesis by regulating EphB receptor trafficking.

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12 December 2020

Fyn kinase-mediated phosphorylation of NMDA receptor NR2B subunit at Tyr1472 is essential for maintenance of neuropathic pain

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12 December 2020

EphB receptors regulate dendritic spine morphogenesis through the recruitment/phosphorylation of focal adhesion kinase and RhoA activation

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12 December 2020

Organization of the presynaptic active zone by ERC2/CAST1-dependent clustering of the tandem PDZ protein syntenin-1.

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12 December 2020

Distinct roles for ephrinB3 in the formation and function of hippocampal synapses

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12 December 2020

Silencing of EphA3 through a cis interaction with ephrinA5.

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12 December 2020

B-ephrin reverse signaling is required for NMDA-independent long-term potentiation of mossy fibers in the hippocampus.

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12 December 2020

Roles of Eph receptors and ephrins in the normal and damaged adult CNS.

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12 December 2020

The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl-Crk pathway

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12 December 2020

EphB3 receptor and ligand expression in the adult rat brain

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12 December 2020

Intracellular and trans-synaptic regulation of glutamatergic synaptogenesis by EphB receptors.

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12 December 2020

Cell adhesion molecules: signalling functions at the synapse

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12 December 2020

Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation

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12 December 2020

Bidirectional Eph-ephrin signaling during axon guidance

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12 December 2020

The Rac1 guanine nucleotide exchange factor Tiam1 mediates EphB receptor-dependent dendritic spine development

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12 December 2020

Involvement of EphB1 receptor/EphrinB2 ligand in neuropathic pain

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12 December 2020

Postsynaptic ephrinB3 promotes shaft glutamatergic synapse formation.

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12 December 2020

The neuropathic pain triad: neurons, immune cells and glia

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12 December 2020

Upregulation of EphB2 and ephrin-B2 at the optic nerve head of DBA/2J glaucomatous mice coincides with axon loss

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12 December 2020

Ephrin-B reverse signaling promotes structural and functional synaptic maturation in vivo

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12 December 2020

Upregulation and redistribution of ephrinB and EphB receptor in dorsal root ganglion and spinal dorsal horn neurons after peripheral nerve injury and dorsal rhizotomy

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12 December 2020

Pre-synaptic and post-synaptic localization of EphA4 and EphB2 in adult mouse forebrain

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12 December 2020

EphrinB-EphB receptor signaling contributes to neuropathic pain by regulating neural excitability and spinal synaptic plasticity in rats

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12 December 2020

EphB receptors couple dendritic filopodia motility to synapse formation

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12 December 2020

EphrinB2 induces tyrosine phosphorylation of NR2B via Src-family kinases during inflammatory hyperalgesia.

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12 December 2020

Activation of peripheral ephrinBs/EphBs signaling induces hyperalgesia through a MAPKs-mediated mechanism in mice

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12 December 2020

Signaling by synaptogenic molecules.

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12 December 2020

Regional and cellular distribution of ephrin-B1 in adult mouse brain.

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12 December 2020

Targeted mutation of EphB1 receptor prevents development of neuropathic hyperalgesia and physical dependence on morphine in mice

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12 December 2020

Bidirectional modulation of synaptic functions by Eph/ephrin signaling.

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12 December 2020

Serine phosphorylation of ephrinB2 regulates trafficking of synaptic AMPA receptors

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12 December 2020

Ephrin-B3 reverse signaling through Grb4 and cytoskeletal regulators mediates axon pruning

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12 December 2020

A presynaptic homeostatic signaling system composed of the Eph receptor, ephexin, Cdc42, and CaV2.1 calcium channels.

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12 December 2020

Neuropathic pain: a maladaptive response of the nervous system to damage

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12 December 2020

An in vivo mouse model of long-term potentiation at synapses between primary afferent C-fibers and spinal dorsal horn neurons: essential role of EphB1 receptor

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12 December 2020

The emerging role of synaptic cell-adhesion pathways in the pathogenesis of autism spectrum disorders

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12 December 2020

Early changes in hippocampal Eph receptors precede the onset of memory decline in mouse models of Alzheimer's disease.

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12 December 2020

Focal adhesion kinase acts downstream of EphB receptors to maintain mature dendritic spines by regulating cofilin activity

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12 December 2020

Ephrin-B1 and ephrin-B2 mediate EphB-dependent presynaptic development via syntenin-1.

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12 December 2020

Phosphatidylinositol 3-kinase mediates pain behaviors induced by activation of peripheral ephrinBs/EphBs signaling in mice

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12 December 2020

To build a synapse: signaling pathways in neuromuscular junction assembly

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12 December 2020

Region-specific contribution of ephrin-B and Wnt signaling to receptive field plasticity in developing optic tectum

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12 December 2020

EphrinBs/EphBs signaling is involved in modulation of spinal nociceptive processing through a mitogen-activated protein kinases-dependent mechanism

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12 December 2020

Trans-synaptic EphB2-ephrin-B3 interaction regulates excitatory synapse density by inhibition of postsynaptic MAPK signaling

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12 December 2020

Architecture of Eph receptor clusters

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12 December 2020

Ephrin-B3 regulates glutamate receptor signaling at hippocampal synapses

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12 December 2020

Z-360, a novel therapeutic agent for pancreatic cancer, prevents up-regulation of ephrin B1 gene expression and phosphorylation of NR2B via suppression of interleukin-1 β production in a cancer-induced pain model in mice

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12 December 2020

EphB-mediated degradation of the RhoA GEF Ephexin5 relieves a developmental brake on excitatory synapse formation

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12 December 2020

Nociceptor-expressed ephrin-B2 regulates inflammatory and neuropathic pain

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12 December 2020

Reversing EphB2 depletion rescues cognitive functions in Alzheimer model

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12 December 2020

Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis

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12 December 2020

Dynamics of the Rho-family small GTPases in actin regulation and motility

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12 December 2020

Preferential control of basal dendritic protrusions by EphB2

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12 December 2020

EphB controls NMDA receptor function and synaptic targeting in a subunit-specific manner

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12 December 2020

Involvement of EphB1 receptor/ephrinB1 ligand in bone cancer pain

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12 December 2020

PSD-95 and PSD-93 play critical but distinct roles in synaptic scaling up and down.

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12 December 2020

Blocking EphB1 Receptor Forward Signaling in Spinal Cord Relieves Bone Cancer Pain and Rescues Analgesic Effect of Morphine Treatment in Rodents

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12 December 2020

Eph receptors and ephrins in neuron-astrocyte communication at synapses

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12 December 2020

A dual shaping mechanism for postsynaptic ephrin-B3 as a receptor that sculpts dendrites and synapses.

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12 December 2020

Looking forward to EphB signaling in synapses

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12 December 2020

The postsynaptic organization of synapses

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12 December 2020

Synaptic dysfunction in neurodevelopmental disorders associated with autism and intellectual disabilities

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12 December 2020

Alzheimer mechanisms and therapeutic strategies

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12 December 2020

Ephrin regulation of synapse formation, function and plasticity

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12 December 2020

De novo mutations revealed by whole-exome sequencing are strongly associated with autism

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12 December 2020

EphBs: an integral link between synaptic function and synaptopathies

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12 December 2020

Disrupted surface cross-talk between NMDA and Ephrin-B2 receptors in anti-NMDA encephalitis

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12 December 2020

Anti-NMDA-receptor antibody detected in encephalitis, schizophrenia, and narcolepsy with psychotic features

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12 December 2020

Anti-NMDA receptor encephalitis antibody binding is dependent on amino acid identity of a small region within the GluN1 amino terminal domain.

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12 December 2020

PI3K contributed to modulation of spinal nociceptive information related to ephrinBs/EphBs

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12 December 2020

A chemical genetic approach reveals distinct EphB signaling mechanisms during brain development

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12 December 2020

Involvement of EphB1 receptors signalling in models of inflammatory and neuropathic pain

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12 December 2020

Postsynaptic density scaffold SAP102 regulates cortical synapse development through EphB and PAK signaling pathway

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12 December 2020

Eph/ephrin recognition and the role of Eph/ephrin clusters in signaling initiation

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12 December 2020

The role of MuSK in synapse formation and neuromuscular disease

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12 December 2020

Protective effects of EphB2 on Aβ1-42 oligomer-induced neurotoxicity and synaptic NMDA receptor signaling in hippocampal neurons

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12 December 2020

EphrinB-EphB receptor signaling contributes to bone cancer pain via Toll-like receptor and proinflammatory cytokines in rat spinal cord

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12 December 2020

A novel autoantibody against ephrin type B receptor 2 in acute necrotizing encephalopathy.

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12 December 2020

AMPARs and synaptic plasticity: the last 25 years

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12 December 2020

Mosaic analysis with double markers (MADM) in mice

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12 December 2020

Neuropathic pain: mechanisms and their clinical implications

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12 December 2020

Cortical abnormalities and non-spatial learning deficits in a mouse model of CranioFrontoNasal syndrome.

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12 December 2020

Spinal ephrinB/EphB signalling contributed to remifentanil-induced hyperalgesia via NMDA receptor

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12 December 2020

Blockade of EphA4 signaling ameliorates hippocampal synaptic dysfunctions in mouse models of Alzheimer's disease

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12 December 2020

Mechanisms of boundary formation by Eph receptor and ephrin signaling

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12 December 2020

PKA is required for the modulation of spinal nociceptive information related to ephrinB-EphB signaling in mice

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12 December 2020

Rheb activation disrupts spine synapse formation through accumulation of syntenin in tuberous sclerosis complex

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12 December 2020

EphrinB-EphB signaling regulates spinal pain processing via PKCγ.

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12 December 2020

Regulation of AMPA receptor subunit GluA1 surface expression by PAK3 phosphorylation

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12 December 2020

Anchoring and synaptic stability of PSD-95 is driven by ephrin-B3.

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12 December 2020

Increasing the Receptor Tyrosine Kinase EphB2 Prevents Amyloid-β-induced Depletion of Cell Surface Glutamate Receptors by a Mechanism That Requires the PDZ-binding Motif of EphB2 and Neuronal Activity

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12 December 2020

Topographic Mapping of the Synaptic Cleft into Adhesive Nanodomains.

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12 December 2020

Mechanisms of ephrin-Eph signalling in development, physiology and disease.

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12 December 2020

Dendritic spine actin dynamics in neuronal maturation and synaptic plasticity.

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12 December 2020

Astrocytic Ephrin-B1 Regulates Synapse Remodeling Following Traumatic Brain Injury

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12 December 2020

Ephrin-B3 coordinates timed axon targeting and amygdala spinogenesis for innate fear behaviour

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12 December 2020

The amyloid hypothesis of Alzheimer's disease at 25 years

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12 December 2020

Ephrin-B2 prevents N-methyl-D-aspartate receptor antibody effects on memory and neuroplasticity.

1 reference

12 December 2020

Amygdala EphB2 Signaling Regulates Glutamatergic Neuron Maturation and Innate Fear.

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12 December 2020

Blocking the Interaction between EphB2 and ADDLs by a Small Peptide Rescues Impaired Synaptic Plasticity and Memory Deficits in a Mouse Model of Alzheimer's Disease

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12 December 2020

Reducing expression of synapse-restricting protein Ephexin5 ameliorates Alzheimer's-like impairment in mice

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12 December 2020

Overexpression of EphB2 in hippocampus rescues impaired NMDA receptors trafficking and cognitive dysfunction in Alzheimer model

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12 December 2020

Extracellular phosphorylation of a receptor tyrosine kinase controls synaptic localization of NMDA receptors and regulates pathological pain

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12 December 2020

Filopodia Conduct Target Selection in Cortical Neurons Using Differences in Signal Kinetics of a Single Kinase.

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12 December 2020

Functional Consequences of Synapse Remodeling Following Astrocyte-Specific Regulation of Ephrin-B1 in the Adult Hippocampus

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12 December 2020

10.1016/J.MCN.2018.07.002

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30031105%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

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13 April 2020

PubMed publication ID

30031105

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30031105%20AND%20SRC:MED&resulttype=core&format=json