(Q90237254)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32160287%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

title

Demonstration of brain region-specific neuronal vulnerability in human iPSC-based model of familial Parkinson's disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32160287%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

1 reference

Razvan-Marius Brazdis

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32160287%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Julian Alecu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32160287%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Daniel Marsch

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32160287%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Annika Dahms

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32160287%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Katrin Simmnacher

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32160287%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Sandra Lörentz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32160287%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Anna Brendler

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32160287%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Yanni Schneider

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32160287%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Franz Marxreiter

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32160287%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Laurent Roybon

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32160287%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Beate Winner

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32160287%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Wei Xiang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32160287%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Iryna Prots

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32160287%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

publication date

11 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32160287%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

published in

Human Molecular Genetics

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32160287%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

12 April 2020

start time

11 March 2020

1 reference

April 2022 Public Data File from Crossref

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC7206857/fullTextXML

inferred from PubMed Central ID database lookup

cites work

The role of D1-dopamine receptor in working memory: local injections of dopamine antagonists into the prefrontal cortex of rhesus monkeys performing an oculomotor delayed-response task

1 reference

12 December 2020

Alpha-synuclein in Lewy bodies

1 reference

12 December 2020

Basic fibroblast growth factor (Fgf2) is necessary for cell proliferation and neurogenesis in the developing cerebral cortex.

1 reference

12 December 2020

1 reference

12 December 2020

Staging of brain pathology related to sporadic Parkinson's disease

1 reference

12 December 2020

Description of Parkinson's disease as a clinical syndrome.

1 reference

12 December 2020

No global loss of neocortical neurons in parkinson's disease: A quantitative stereological study

1 reference

12 December 2020

Mechanisms of neural cell death: implications for development of neuroprotective treatment strategies

1 reference

12 December 2020

Effects of nitration on the structure and aggregation of alpha-synuclein

1 reference

12 December 2020

Dopaminergic contribution to the regulation of emotional perception

1 reference

12 December 2020

Self-renewing and differentiating properties of cortical neural stem cells are selectively regulated by basic fibroblast growth factor (FGF) signaling via specific FGF receptors

1 reference

12 December 2020

Different species of alpha-synuclein oligomers induce calcium influx and seeding.

1 reference

12 December 2020

Genomic investigation of alpha-synuclein multiplication and parkinsonism

1 reference

12 December 2020

Non-motor symptoms of Parkinson's disease: dopaminergic pathophysiology and treatment

1 reference

12 December 2020

Role of post-translational modifications in modulating the structure, function and toxicity of alpha-synuclein: implications for Parkinson's disease pathogenesis and therapies

1 reference

12 December 2020

α-Synuclein and dopamine at the crossroads of Parkinson's disease

1 reference

12 December 2020

Vulnerability of mesostriatal dopaminergic neurons in Parkinson's disease

1 reference

12 December 2020

In vivo demonstration that alpha-synuclein oligomers are toxic

1 reference

12 December 2020

LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress

1 reference

12 December 2020

Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus

1 reference

12 December 2020

SNCA triplication Parkinson's patient's iPSC-derived DA neurons accumulate α-synuclein and are susceptible to oxidative stress

1 reference

12 December 2020

Neuronal vulnerability in Parkinson's disease.

1 reference

12 December 2020

Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease.

1 reference

12 December 2020

Specification of midbrain dopamine neurons from primate pluripotent stem cells

1 reference

12 December 2020

Lipid peroxidation product 4-hydroxy-2-nonenal promotes seeding-capable oligomer formation and cell-to-cell transfer of α-synuclein

1 reference

12 December 2020

The many faces of α-synuclein: from structure and toxicity to therapeutic target

1 reference

12 December 2020

Oxidative stress-induced posttranslational modifications of alpha-synuclein: specific modification of alpha-synuclein by 4-hydroxy-2-nonenal increases dopaminergic toxicity.

1 reference

12 December 2020

Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling

1 reference

12 December 2020

α-Synuclein oligomers impair neuronal microtubule-kinesin interplay.

1 reference

12 December 2020

Gene dosage-dependent rescue of HSP neurite defects in SPG4 patients' neurons

1 reference

12 December 2020

Isolation of human induced pluripotent stem cell-derived dopaminergic progenitors by cell sorting for successful transplantation

1 reference

12 December 2020

iPSC-derived neurons from GBA1-associated Parkinson's disease patients show autophagic defects and impaired calcium homeostasis

1 reference

12 December 2020

The prevalence of Parkinson's disease: a systematic review and meta-analysis

1 reference

12 December 2020

A 6.4 Mb duplication of the α-synuclein locus causing frontotemporal dementia and Parkinsonism: phenotype-genotype correlations

1 reference

12 December 2020

Dopamine midbrain neurons in health and Parkinson's disease: emerging roles of voltage-gated calcium channels and ATP-sensitive potassium channels.

1 reference

12 December 2020

iPSC-derived dopamine neurons reveal differences between monozygotic twins discordant for Parkinson's disease

1 reference

12 December 2020

Mitochondrial alterations by PARKIN in dopaminergic neurons using PARK2 patient-specific and PARK2 knockout isogenic iPSC lines

1 reference

12 December 2020

1 reference

12 December 2020

Dopaminergic Modulation of Decision Making and Subjective Well-Being

1 reference

12 December 2020

Autosomal dominant Parkinson's disease caused by SNCA duplications

1 reference

12 December 2020

Sensitive western blotting for detection of endogenous Ser129-phosphorylated α-synuclein in intracellular and extracellular spaces

1 reference

12 December 2020

Elevated α-synuclein caused by SNCA gene triplication impairs neuronal differentiation and maturation in Parkinson's patient-derived induced pluripotent stem cells

1 reference

12 December 2020

α-Synuclein-induced lysosomal dysfunction occurs through disruptions in protein trafficking in human midbrain synucleinopathy models

1 reference

12 December 2020

Implication of Alpha-Synuclein Phosphorylation at S129 in Synucleinopathies: What Have We Learned in the Last Decade?

1 reference

12 December 2020

Functional Impairment in Miro Degradation and Mitophagy Is a Shared Feature in Familial and Sporadic Parkinson's Disease

1 reference

12 December 2020

Parkin and PINK1 Patient iPSC-Derived Midbrain Dopamine Neurons Exhibit Mitochondrial Dysfunction and α-Synuclein Accumulation

1 reference

12 December 2020

A de novo compound targeting α-synuclein improves deficits in models of Parkinson's disease

1 reference

12 December 2020

Alpha-synuclein structure, functions, and interactions

1 reference

12 December 2020

Enhanced derivation of human pluripotent stem cell-derived cortical glutamatergic neurons by a small molecule

1 reference

12 December 2020

Creation of a library of induced pluripotent stem cells from Parkinsonian patients.

1 reference

12 December 2020

Human iPS cell-derived dopaminergic neurons function in a primate Parkinson's disease model.

1 reference

12 December 2020

Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson's disease

1 reference

12 December 2020

On Cell Loss and Selective Vulnerability of Neuronal Populations in Parkinson's Disease.

1 reference

12 December 2020

Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson's Disease

1 reference

12 December 2020

α-Synuclein oligomers induce early axonal dysfunction in human iPSC-based models of synucleinopathies

1 reference

12 December 2020

Need for high-resolution Genetic Analysis in iPSC: Results and Lessons from the ForIPS Consortium

1 reference

12 December 2020

Cellular alterations identified in pluripotent stem cell-derived midbrain spheroids generated from a female patient with progressive external ophthalmoplegia and parkinsonism who carries a novel variation (p.Q811R) in the POLG1 gene

1 reference

12 December 2020

Modeling Cell-Cell Interactions in Parkinson's Disease Using Human Stem Cell-Based Models

1 reference

12 December 2020