(Q90297013)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30018565%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

title

Oxidative Stress: A Major Player in Cerebrovascular Alterations Associated to Neurodegenerative Events (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30018565%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30018565%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Paula I Moreira

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30018565%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

publication date

3 July 2018

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12 April 2020

published in

Frontiers in Physiology

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12 April 2020

volume

1 reference

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12 April 2020

page(s)

806

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Creative Commons Attribution 4.0 International

12 April 2020

start time

3 July 2018

1 reference

April 2022 Public Data File from Crossref

copyrighted

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cites work

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Oxygen consumption of the living human brain measured after a single inhalation of positron emitting oxygen

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Oxidative stress in mitochondria: its relationship to cellular Ca2+ homeostasis, cell death, proliferation, and differentiation

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Energetic response of coronary endothelial cells to hypoxia

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Fatty acids are not an important fuel for coronary microvascular endothelial cells

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12 December 2020

Effect of aging on the blood-brain barrier

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12 December 2020

Enzymatic protection against peroxidative damage in isolated brain capillaries

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12 December 2020

Energy turnover of vascular endothelial cells

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12 December 2020

Tumour necrosis factor α activates a p22phox-based NADH oxidase in vascular smooth muscle

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12 December 2020

Role of potassium channels in regulation of cerebral vascular tone

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12 December 2020

Potential role of cerebral glutathione in the maintenance of blood-brain barrier integrity in rat.

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Mitochondrial free radical generation, oxidative stress, and aging

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12 December 2020

Mitochondrial uncoupling proteins: from mitochondria to the regulation of energy balance

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12 December 2020

Thrombin-induced MCP-1 expression involves activation of the p22phox-containing NADPH oxidase in human vascular smooth muscle cells

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12 December 2020

Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: Role of the p22(phox)-containing NADPH oxidase

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12 December 2020

Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment

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12 December 2020

Effects of NADH and NADPH on superoxide levels and cerebral vascular tone

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12 December 2020

Nitric oxide, mitochondria, and cell death

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12 December 2020

Hypertension and hypercholesterolaemia as risk factors for Alzheimer's disease: potential for pharmacological intervention

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12 December 2020

Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension

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12 December 2020

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12 December 2020

Mitochondrial sources of H2O2 generation play a key role in flow-mediated dilation in human coronary resistance arteries

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12 December 2020

Aging: a theory based on free radical and radiation chemistry

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12 December 2020

The impact of cerebrovascular lesions in Alzheimer disease--a comparative autopsy study

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12 December 2020

Hydrogen peroxide induces apoptosis in cerebral vascular smooth muscle cells: possible relation to neurodegenerative diseases and strokes

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12 December 2020

Cerebrovascular dysfunction in Zucker obese rats is mediated by oxidative stress and protein kinase C.

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12 December 2020

Exogenous NADPH increases cerebral blood flow through NADPH oxidase-dependent and -independent mechanisms

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12 December 2020

NADPH-oxidase-derived reactive oxygen species mediate the cerebrovascular dysfunction induced by the amyloid beta peptide.

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12 December 2020

NADPH oxidase activity and function are profoundly greater in cerebral versus systemic arteries

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12 December 2020

Nox1 is involved in angiotensin II-mediated hypertension: a study in Nox1-deficient mice

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12 December 2020

Vascular remodeling versus amyloid beta-induced oxidative stress in the cerebrovascular dysfunctions associated with Alzheimer's disease.

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12 December 2020

Targeting antioxidants to mitochondria: a new therapeutic direction

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12 December 2020

Neurovascular coupling in the normal brain and in hypertension, stroke, and Alzheimer disease

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12 December 2020

Angiotensin II attenuates endothelium-dependent responses in the cerebral microcirculation through nox-2-derived radicals

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12 December 2020

Mitochondria as signaling organelles in the vascular endothelium

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12 December 2020

Pharmacologic blockade of angiopoietin-2 is efficacious against model hemangiomas in mice

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12 December 2020

Mitochondria: dynamic organelles in disease, aging, and development

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12 December 2020

Vascular NAD(P)H oxidase mediates endothelial dysfunction in basilar arteries from Otsuka Long-Evans Tokushima Fatty (OLETF) rats

1 reference

12 December 2020

Update on hypertension and Alzheimer's disease

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12 December 2020

Free radicals and antioxidants in normal physiological functions and human disease

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12 December 2020

Cerebrovascular nitrosative stress mediates neurovascular and endothelial dysfunction induced by angiotensin II.

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12 December 2020

Increased mitochondrial H2O2 production promotes endothelial NF-kappaB activation in aged rat arteries

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12 December 2020

Nox2-derived reactive oxygen species mediate neurovascular dysregulation in the aging mouse brain

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12 December 2020

Vascular aging in the longest-living rodent, the naked mole rat.

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12 December 2020

Role of reactive oxygen species in modulation of Nrf2 following ischemic reperfusion injury

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12 December 2020

Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling

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12 December 2020

Astrocyte control of the cerebrovasculature.

1 reference

12 December 2020

Oxidative stress and cerebrovascular dysfunction in mouse models of Alzheimer's disease

1 reference

12 December 2020

NADPH oxidase plays a central role in blood-brain barrier damage in experimental stroke

1 reference

12 December 2020

Activation of Nrf2-ARE pathway in brain after traumatic brain injury

1 reference

12 December 2020

Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein

1 reference

12 December 2020

The blood-brain barrier in health and chronic neurodegenerative disorders

1 reference

12 December 2020

Dysregulation of mitochondrial biogenesis in vascular endothelial and smooth muscle cells of aged rats

1 reference

12 December 2020

Reactive species: a cell damaging rout assisting to chemical carcinogens

1 reference

12 December 2020

1 reference

12 December 2020

Manganese superoxide dismutase and aldehyde dehydrogenase deficiency increase mitochondrial oxidative stress and aggravate age-dependent vascular dysfunction

1 reference

12 December 2020

Distinct roles of Nox1 and Nox4 in basal and angiotensin II-stimulated superoxide and hydrogen peroxide production

1 reference

12 December 2020

Regulation of NADPH oxidase in vascular endothelium: the role of phospholipases, protein kinases, and cytoskeletal proteins

1 reference

12 December 2020

NADPH oxidase activity is higher in cerebral versus systemic arteries of four animal species: role of Nox2.

1 reference

12 December 2020

Identification of structural elements in Nox1 and Nox4 controlling localization and activity.

1 reference

12 December 2020

Mitochondria-targeted antioxidants in the treatment of disease

1 reference

12 December 2020

RNA oxidation in Alzheimer disease and related neurodegenerative disorders

1 reference

12 December 2020

Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease

1 reference

12 December 2020

An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer's disease

1 reference

12 December 2020

AMPK in the brain: its roles in energy balance and neuroprotection

1 reference

12 December 2020

The Nrf2-ARE cytoprotective pathway in astrocytes

1 reference

12 December 2020

Importance of NOX1 for angiotensin II-induced cerebrovascular superoxide production and cortical infarct volume following ischemic stroke

1 reference

12 December 2020

Fulvene-5 potently inhibits NADPH oxidase 4 and blocks the growth of endothelial tumors in mice.

1 reference

12 December 2020

Contribution of hypoxia to Alzheimer's disease: is HIF-1alpha a mediator of neurodegeneration?

1 reference

12 December 2020

Consequences of long-term oral administration of the mitochondria-targeted antioxidant MitoQ to wild-type mice.

1 reference

12 December 2020

Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson's disease.

1 reference

12 December 2020

Oxidative stress and its role in the pathogenesis of ischaemic stroke

1 reference

12 December 2020

Direct activation of RhoA by reactive oxygen species requires a redox-sensitive motif

1 reference

12 December 2020

Involvement of NADPH oxidase in age-associated cardiac remodeling

1 reference

12 December 2020

Augmented superoxide production by Nox2-containing NADPH oxidase causes cerebral artery dysfunction during hypercholesterolemia.

1 reference

12 December 2020

Oxidative stress increases blood-brain barrier permeability and induces alterations in occludin during hypoxia-reoxygenation.

1 reference

12 December 2020

Vascular dysfunction in cerebrovascular disease: mechanisms and therapeutic intervention

1 reference

12 December 2020

Mitochondria-targeted antioxidants protect against amyloid-beta toxicity in Alzheimer's disease neurons

1 reference

12 December 2020

Mitochondrial impairment contributes to cocaine-induced cardiac dysfunction: Prevention by the targeted antioxidant MitoQ.

1 reference

12 December 2020

Seasonal reduction in physical activity and flow-mediated dilation in children.

1 reference

12 December 2020

A novel and specific NADPH oxidase-1 (Nox1) small-molecule inhibitor blocks the formation of functional invadopodia in human colon cancer cells

1 reference

12 December 2020

Distinct cerebral perfusion patterns in FTLD and AD

1 reference

12 December 2020

Neuroprotection by a mitochondria-targeted drug in a Parkinson's disease model

1 reference

12 December 2020

Mitochondrial preconditioning: a potential neuroprotective strategy

1 reference

12 December 2020

Pericytes regulate the blood-brain barrier

1 reference

12 December 2020

Amyloid Beta induces oxidative stress-mediated blood-brain barrier changes in capillary amyloid angiopathy.

1 reference

12 December 2020

Mitochondria-targeted antioxidants as therapies

1 reference

12 December 2020

Scavenger receptor CD36 is essential for the cerebrovascular oxidative stress and neurovascular dysfunction induced by amyloid-beta

1 reference

12 December 2020

Mitochondria-targeted small molecule therapeutics and probes

1 reference

12 December 2020

Endothelial Nox4 NADPH oxidase enhances vasodilatation and reduces blood pressure in vivo.

1 reference

12 December 2020

Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets

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12 December 2020

Regulation of VEGF-induced endothelial cell migration by mitochondrial reactive oxygen species

1 reference

12 December 2020

Cyanide preconditioning protects brain endothelial and NT2 neuron-like cells against glucotoxicity: role of mitochondrial reactive oxygen species and HIF-1α

1 reference

12 December 2020

Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders

1 reference

12 December 2020

The Nox family of NADPH oxidases: friend or foe of the vascular system?

1 reference

12 December 2020

Resolution of mitochondrial oxidative stress rescues coronary collateral growth in Zucker obese fatty rats.

1 reference

12 December 2020

Oxidative stress and cerebral endothelial cells: regulation of the blood-brain-barrier and antioxidant based interventions

1 reference

12 December 2020

Metabolic alterations induced by sucrose intake and Alzheimer's disease promote similar brain mitochondrial abnormalities

1 reference

12 December 2020

Anti-invasive adjuvant therapy with imipramine blue enhances chemotherapeutic efficacy against glioma

1 reference

12 December 2020

Morphological and pathological evolution of the brain microcirculation in aging and Alzheimer's disease

1 reference

12 December 2020

The early contribution of cerebrovascular factors to the pathogenesis of Alzheimer's disease

1 reference

12 December 2020

The vascular factor in Alzheimer's disease: a study in Golgi technique and electron microscopy

1 reference

12 December 2020

Adverse alterations in mitochondrial function contribute to type 2 diabetes mellitus-related endothelial dysfunction in humans

1 reference

12 December 2020

Reactive oxygen species in health and disease

1 reference

12 December 2020

Mitochondria in vascular health and disease

1 reference

12 December 2020

Cellular and molecular mechanisms of mitochondrial function

1 reference

12 December 2020

Vascular disease and dementias: paradigm shifts to drive research in new directions

1 reference

12 December 2020

High glucose condition increases NADPH oxidase activity in endothelial microparticles that promote vascular inflammation.

1 reference

12 December 2020

Gender differences in brain susceptibility to oxidative stress are mediated by levels of paraoxonase-2 expression

1 reference

12 December 2020

Type 2 diabetic and Alzheimer's disease mice present similar behavioral, cognitive, and vascular anomalies

1 reference

12 December 2020

Triggers and effectors of oxidative stress at blood-brain barrier level: relevance for brain ageing and neurodegeneration

1 reference

12 December 2020

Mitochondria and endothelial function

1 reference

12 December 2020

Endothelin-converting enzyme-1 activity, endothelin-1 production, and free radical-dependent vasoconstriction in Alzheimer's disease

1 reference

12 December 2020

Increased susceptibility to amyloid-β toxicity in rat brain microvascular endothelial cells under hyperglycemic conditions

1 reference

12 December 2020

Circulating endothelin-1 alters critical mechanisms regulating cerebral microcirculation

1 reference

12 December 2020

Sugar for the brain: the role of glucose in physiological and pathological brain function

1 reference

12 December 2020

Neurovascular abnormalities in humans and mice with Huntington's disease

1 reference

12 December 2020

Nox2-induced production of mitochondrial superoxide in angiotensin II-mediated endothelial oxidative stress and hypertension

1 reference

12 December 2020

High glucose-induced mitochondrial respiration and reactive oxygen species in mouse cerebral pericytes is reversed by pharmacological inhibition of mitochondrial carbonic anhydrases: Implications for cerebral microvascular disease in diabetes

1 reference

12 December 2020

NADPH oxidases in vascular pathology

1 reference

12 December 2020

The pathobiology of vascular dementia

1 reference

12 December 2020

Genomic and non-genomic regulation of PGC1 isoforms by estrogen to increase cerebral vascular mitochondrial biogenesis and reactive oxygen species protection

1 reference

12 December 2020

Sex differences in the structural connectome of the human brain

1 reference

12 December 2020

Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase.

1 reference

12 December 2020

Disruption of the blood-brain barrier in Parkinson's disease: curse or route to a cure?

1 reference

12 December 2020

Nanoscale drug delivery systems and the blood-brain barrier

1 reference

12 December 2020

Simulated microgravity-induced mitochondrial dysfunction in rat cerebral arteries

1 reference

12 December 2020

Mitochondria-targeted antioxidant (MitoQ) ameliorates age-related arterial endothelial dysfunction in mice

1 reference

12 December 2020

Development, appraisal, validation and implementation of a consensus protocol for the assessment of cerebral amyloid angiopathy in post-mortem brain tissue

1 reference

12 December 2020

Antioxidant effects of statins in patients with atherosclerotic cerebrovascular disease

1 reference

12 December 2020

Mitochondria, endothelial cell function, and vascular diseases

1 reference

12 December 2020

Mitochondrial mechanisms in cerebral vascular control: shared signaling pathways with preconditioning

1 reference

12 December 2020

Endothelial NADPH oxidases: which NOX to target in vascular disease?

1 reference

12 December 2020

Empathy: gender effects in brain and behavior

1 reference

12 December 2020

The key role of transient receptor potential melastatin-2 channels in amyloid-β-induced neurovascular dysfunction.

1 reference

12 December 2020

The role of reactive oxygen species in microvascular remodeling

1 reference

12 December 2020

The blood-brain barrier

1 reference

12 December 2020

Blood-brain barrier breakdown in the aging human hippocampus

1 reference

12 December 2020

Trends in Mitochondrial Therapeutics for Neurological Disease

1 reference

12 December 2020

Contribution of reactive oxygen species to cerebral amyloid angiopathy, vasomotor dysfunction, and microhemorrhage in aged Tg2576 mice

1 reference

12 December 2020

Progressive gender differences of structural brain networks in healthy adults: a longitudinal, diffusion tensor imaging study

1 reference

12 December 2020

Cerebrospinal fluid biomarkers of neurovascular dysfunction in mild dementia and Alzheimer's disease

1 reference

12 December 2020

The role of mitochondrial disturbances in Alzheimer, Parkinson and Huntington diseases

1 reference

12 December 2020

Mitochondrial Oxidative Stress, Mitochondrial DNA Damage and Their Role in Age-Related Vascular Dysfunction

1 reference

12 December 2020

Dynamics of enhanced mitochondrial respiration in female compared with male rat cerebral arteries

1 reference

12 December 2020

Targeting cerebrovascular impairments in Huntington's disease: a novel treatment perspective.

1 reference

12 December 2020

Molecular mechanism of endothelial and vascular aging: implications for cardiovascular disease.

1 reference

12 December 2020

Regional Heterogeneity of Cerebral Microvessels and Brain Susceptibility to Oxidative Stress

1 reference

12 December 2020

Transient Cerebral Ischemia Promotes Brain Mitochondrial Dysfunction and Exacerbates Cognitive Impairments in Young 5xFAD Mice

1 reference

12 December 2020

The analysis of cardio-respiratory signals and cerebral autoregulation based on CO2 reactivity with healthy subjects and Parkinson's patients

1 reference

12 December 2020

Neurovascular dysfunction and neurodegeneration in dementia and Alzheimer's disease

1 reference

12 December 2020

NADPH oxidases: key modulators in aging and age-related cardiovascular diseases?

1 reference

12 December 2020

The Cellular Phase of Alzheimer's Disease

1 reference

12 December 2020

Gender differences in white matter pathology and mitochondrial dysfunction in Alzheimer's disease with cerebrovascular disease

1 reference

12 December 2020

Microvascular Dysfunction and Cognitive Impairment.

1 reference

12 December 2020

Neurovascular and Cognitive failure in Alzheimer's Disease: Benefits of Cardiovascular Therapy

1 reference

12 December 2020

Cerebral Small Vessel Disease: Targeting Oxidative Stress as a Novel Therapeutic Strategy?

1 reference

12 December 2020

Morphogens and blood-brain barrier function in health and disease

1 reference

12 December 2020

Role of Mitochondria in Cerebral Vascular Function: Energy Production, Cellular Protection, and Regulation of Vascular Tone.

1 reference

12 December 2020

Metabolic Syndrome as a Risk Factor for Alzheimer's Disease: Is Aβ a Crucial Factor in Both Pathologies?

1 reference

12 December 2020

Middle-Aged Diabetic Females and Males Present Distinct Susceptibility to Alzheimer Disease-like Pathology.

1 reference

12 December 2020

The mitochondria-targeted antioxidant MitoQ modulates oxidative stress, inflammation and leukocyte-endothelium interactions in leukocytes isolated from type 2 diabetic patients

1 reference

12 December 2020

Perivascular macrophages mediate the neurovascular and cognitive dysfunction associated with hypertension.

1 reference

12 December 2020

Impaired neurovascular coupling in aging and Alzheimer's disease: Contribution of astrocyte dysfunction and endothelial impairment to cognitive decline

1 reference

12 December 2020

Activated microglia induce the production of reactive oxygen species and promote apoptosis of co-cultured retinal microvascular pericytes

1 reference

12 December 2020

Structural and physiological neurovascular changes in idiopathic Parkinson's disease and its clinical phenotypes

1 reference

12 December 2020

Neurovascular uncoupling in the triple transgenic model of Alzheimer's disease: Impaired cerebral blood flow response to neuronal-derived nitric oxide signaling

1 reference

12 December 2020

Energy and the Alzheimer brain

1 reference

12 December 2020

Reactive oxygen species: key regulators in vascular health and diseases.

1 reference

12 December 2020

Demonstration of impaired neurovascular coupling responses in TG2576 mouse model of Alzheimer's disease using functional laser speckle contrast imaging.

1 reference

12 December 2020

Disease Highlights the Cellular Diversity of Neurovascular Units: Sign in Stranger.

1 reference

12 December 2020

Aging: Molecular Pathways and Implications on the Cardiovascular System.

1 reference

12 December 2020

The Future Challenge of Reactive Oxygen Species (ROS) in Hypertension: From Bench to Bed Side

1 reference

12 December 2020

3D morphological analysis of the mouse cerebral vasculature: Comparison of in vivo and ex vivo methods

1 reference

12 December 2020

Numerical and length densities of microvessels in the human brain: Correlation with preferential orientation of microvessels in the cerebral cortex, subcortical grey matter and white matter, pons and cerebellum.

1 reference

12 December 2020

Oxidative stress in cerebral small vessel disease. Role of reactive species

1 reference

12 December 2020

Vascular and Tissue Changes of Magnetic Susceptibility in the Mouse Brain After Transient Cerebral Ischemia.

1 reference

12 December 2020

Identifiers

DOI

10.3389/FPHYS.2018.00806

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30018565%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30018565%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

PubMed publication ID

30018565

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30018565%20AND%20SRC:MED&resulttype=core&format=json