(Q88959360)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29859882%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

title

The impact of sex as a biological variable in the search for novel antidepressants (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29859882%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

1 reference

Alexia V Williams

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29859882%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Brian C Trainor

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29859882%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

publication date

31 May 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29859882%20AND%20SRC:MED&resulttype=core&format=json

Frontiers in Neuroendocrinology

29 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29859882%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29859882%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

page(s)

107-117

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29859882%20AND%20SRC:MED&resulttype=core&format=json

Exposure to chronic mild stress prevents kappa opioid-mediated reinstatement of cocaine and nicotine place preference

29 March 2020

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7 January 2021

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Sex Differences in Kappa Opioid Receptor Function and Their Potential Impact on Addiction

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Dynorphin Is a Specific Endogenous Ligand of the κ Opioid Receptor

7 January 2021

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Assessing substrates underlying the behavioral effects of antidepressants using the modified rat forced swimming test

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Evidence of dysregulated peripheral oxytocin release among depressed women.

7 January 2021

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Why do you need to move beyond first-line therapy for major depression?

7 January 2021

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Sex differences in animal models of depression and antidepressant response.

7 January 2021

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Sex differences in the pharmacokinetics of antidepressants: influence of female sex hormones and oral contraceptives.

7 January 2021

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Social facilitation of wound healing

7 January 2021

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A randomized add-on trial of an N-methyl-D-aspartate antagonist in treatment-resistant bipolar depression

7 January 2021

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Oxytocin attenuates amygdala responses to emotional faces regardless of valence

7 January 2021

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Effects of intranasal oxytocin on emotional face processing in women

7 January 2021

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7 January 2021

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7 January 2021

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Estrogen receptor beta regulates the expression of tryptophan-hydroxylase 2 mRNA within serotonergic neurons of the rat dorsal raphe nuclei

7 January 2021

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Behavioral and biochemical sensitivity to low doses of ketamine: Influence of estrous cycle in C57BL/6 mice

7 January 2021

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7 January 2021

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Oxytocin Receptors in the Anteromedial Bed Nucleus of the Stria Terminalis Promote Stress-Induced Social Avoidance in Female California Mice

7 January 2021

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Release of oxytocin in the rat central amygdala modulates stress-coping behavior and the release of excitatory amino acids.

7 January 2021

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7 January 2021

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Kappa Opioid Receptor-Induced Aversion Requires p38 MAPK Activation in VTA Dopamine Neurons

7 January 2021

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7 January 2021

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Sex, stress, and mood disorders: at the intersection of adrenal and gonadal hormones.

7 January 2021

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Sex and age differences in the antidepressant-like effect of fluoxetine in the forced swim test.

7 January 2021

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Sex differences in the rapid and the sustained antidepressant-like effects of ketamine in stress-naïve and "depressed" mice exposed to chronic mild stress

7 January 2021

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Neuroanatomical distribution of oxytocin and vasopressin 1a receptors in the socially monogamous coppery titi monkey (Callicebus cupreus).

7 January 2021

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The neuroanatomical distribution of oxytocin receptor binding and mRNA in the male rhesus macaque (Macaca mulatta)

7 January 2021

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Ketamine treatment reverses behavioral and physiological alterations induced by chronic mild stress in rats.

7 January 2021

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Examining the intersection of sex and stress in modelling neuropsychiatric disorders

7 January 2021

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A standardized protocol for repeated social defeat stress in mice.

7 January 2021

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Immediate post-defeat infusions of the noradrenergic receptor antagonist propranolol impair the consolidation of conditioned defeat in male Syrian hamsters.

7 January 2021

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Sex differences in stress-induced social withdrawal: role of brain derived neurotrophic factor in the bed nucleus of the stria terminalis

7 January 2021

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A comparison of antidepressant response in younger and older women

7 January 2021

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Peripheral oxytocin administration buffers autonomic but not behavioral responses to environmental stressors in isolated prairie voles

7 January 2021

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Ketamine for Rapid Reduction of Suicidal Thoughts in Major Depression: A Midazolam-Controlled Randomized Clinical Trial

7 January 2021

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Fear-enhancing effects of septal oxytocin receptors

7 January 2021

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Estrogen receptors and the regulation of neural stress responses

7 January 2021

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Gonadal steroid hormones and the hypothalamo-pituitary-adrenal axis

7 January 2021

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Inhibition of antidepressant demethylation and hydroxylation by fluvoxamine in depressed patients

7 January 2021

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Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress

7 January 2021

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A brief history of the development of antidepressant drugs: from monoamines to glutamate

7 January 2021

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Estrogen receptor-β regulates human tryptophan hydroxylase-2 through an estrogen response element in the 5' untranslated region

7 January 2021

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Estrogen selectively increases tryptophan hydroxylase-2 mRNA expression in distinct subregions of rat midbrain raphe nucleus: association between gene expression and anxiety behavior in the open field

7 January 2021

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Sex Differences in Nucleus Accumbens Transcriptome Profiles Associated with Susceptibility versus Resilience to Subchronic Variable Stress.

7 January 2021

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The influence of depressive symptomatology and perceived stress on plasma and salivary oxytocin before, during and after a support enhancement intervention

7 January 2021

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Vicarious Social Defeat Stress Induces Depression-Related Outcomes in Female Mice.

7 January 2021

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The comparative distribution of forebrain receptors for neurohypophyseal peptides in monogamous and polygamous mice

7 January 2021

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Sex differences in molecular neuroscience: from fruit flies to humans

7 January 2021

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Mouse genomic variation and its effect on phenotypes and gene regulation

7 January 2021

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Prevalence, comorbidity, and service utilization for mood disorders in the United States at the beginning of the twenty-first century

7 January 2021

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Sex differences in antidepressant response in recent antidepressant clinical trials

7 January 2021

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Oxytocin Modulates Neural Circuitry for Social Cognition and Fear in Humans

7 January 2021

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Evoked axonal oxytocin release in the central amygdala attenuates fear response

7 January 2021

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Dynorphin, stress, and depression

7 January 2021

1 reference

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Intranasal Oxytocin Administration Dampens Amygdala Reactivity towards Emotional Faces in Male and Female PTSD Patients.

7 January 2021

1 reference

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Forced swim test: What about females?

7 January 2021

1 reference

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Influence of sex and menopausal status on response, remission, and recurrence in patients with recurrent major depressive disorder treated with venlafaxine extended release or fluoxetine: analysis of data from the PREVENT study

7 January 2021

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Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions

7 January 2021

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A heartfelt response: Oxytocin effects on response to social stress in men and women

7 January 2021

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Modulation of anxiety-related behaviors by mu- and kappa-opioid receptor agonists depends on the social status of mice

7 January 2021

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Anxiety and ethanol consumption in victorious and defeated mice; effect of kappa-opioid receptor activation

7 January 2021

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Sex-specific transcriptional signatures in human depression

7 January 2021

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Oxytocin attenuates amygdala reactivity to fear in generalized social anxiety disorder

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2018.05.003

The kappa opioid receptor: from addiction to depression, and back.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2018.05.003

The long-term effects of stress and kappa opioid receptor activation on conditioned place aversion in male and female California mice

7 January 2021

1 reference

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Stress, sex, and motivated behaviors

7 January 2021

1 reference

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Sex Differences in the Effects of a Kappa Opioid Receptor Antagonist in the Forced Swim Test

7 January 2021

1 reference

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Comorbidity patterns of anxiety and depressive disorders in a large cohort study: the Netherlands Study of Depression and Anxiety (NESDA).

7 January 2021

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The dysphoric component of stress is encoded by activation of the dynorphin kappa-opioid system

7 January 2021

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Activation of the kappa opioid receptor in the dorsal raphe nucleus mediates the aversive effects of stress and reinstates drug seeking

7 January 2021

1 reference

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Oxytocin unlike vasopressin is a stress hormone in the rat

7 January 2021

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Molecular mechanisms and regulation of opioid receptor signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2018.05.003

Antidepressant-like actions of the polyamine site NMDA antagonist, eliprodil (SL-82.0715)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2018.05.003

Glutamate N-methyl-D-aspartate Receptor Antagonists Rapidly Reverse Behavioral and Synaptic Deficits Caused by Chronic Stress Exposure

7 January 2021

1 reference

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Oxytocin increases amygdala reactivity to threatening scenes in females

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YFRNE.2018.05.003

The neuroanatomy of sexual dimorphism in opioid analgesia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2018.05.003

Social preference and maternal defeat-induced social avoidance in virgin female rats: sex differences in involvement of brain oxytocin and vasopressin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2018.05.003

The neuropeptide oxytocin facilitates pro-social behavior and prevents social avoidance in rats and mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2018.05.003

Sex-dependent neural effect of oxytocin during subliminal processing of negative emotion faces

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2018.05.003

Oxytocin's role in anxiety: a critical appraisal

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2018.05.003

Oxytocin and psychotherapy: a pilot study of its physiological, behavioral and subjective effects in males with depression.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2018.05.003

Antidepressant-like effects of kappa-opioid receptor antagonists in the forced swim test in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2018.05.003

Opioid-receptor mRNA expression in the rat CNS: anatomical and functional implications

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2018.05.003

Sex differences in the brain: the not so inconvenient truth

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2018.05.003

Kappa opioid receptor antagonism and prodynorphin gene disruption block stress-induced behavioral responses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2018.05.003

Social defeat stress-induced behavioral responses are mediated by the endogenous kappa opioid system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2018.05.003

Genetic differences among C57BL/6 substrains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2018.05.003

Dizocilpine antagonizes the effect of chronic imipramine on learned helplessness in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2018.05.003

Potential antidepressive properties of amantadine, memantine and bifemelane

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2018.05.003

Antidepressant efficacy of ketamine in treatment-resistant major depression: a two-site randomized controlled trial

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2018.05.003

Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2018.05.003

Oxytocin-oxytocin receptor systems facilitate social defeat posture in male mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2018.05.003

Brain oxytocin inhibits the (re)activity of the hypothalamo-pituitary-adrenal axis in male rats: involvement of hypothalamic and limbic brain regions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2018.05.003

Maternal defence as an emotional stressor in female rats: correlation of neuroendocrine and behavioural parameters and involvement of brain oxytocin

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YFRNE.2018.05.003

Inhibition of cAMP response element-binding protein or dynorphin in the nucleus accumbens produces an antidepressant-like effect.

7 January 2021

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Effectiveness of antidepressant treatments in pre-menopausal versus post-menopausal women: a pilot study on differential effects of sex hormones on antidepressant effects

7 January 2021

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Gender differences in response to differing antidepressant drug classes: two negative studies

7 January 2021

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Psychotomimesis mediated by kappa opiate receptors

7 January 2021

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Oxytocin response to an experimental psychosocial challenge in adults exposed to traumatic experiences during childhood or adolescence

7 January 2021

1 reference

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Comparison of (R)-ketamine and lanicemine on depression-like phenotype and abnormal composition of gut microbiota in a social defeat stress model.

7 January 2021

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Are there differences between women's and men's antidepressant responses?

7 January 2021

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Oxytocin reduces amygdala responses during threat approach

7 January 2021

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Stress-induced reinstatement of cocaine seeking is mediated by the kappa opioid system

7 January 2021

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Effects of kappa opioid receptors on conditioned place aversion and social interaction in males and females

7 January 2021

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Pharmacokinetics of sertraline and its N-demethyl metabolite in elderly and young male and female volunteers.

7 January 2021

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Estrogen-serotonin interactions: implications for affective regulation

7 January 2021

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Sex differences in sensitivity to the depressive-like effects of the kappa opioid receptor agonist U-50488 in rats

7 January 2021

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Oxytocin in the prelimbic medial prefrontal cortex reduces anxiety-like behavior in female and male rats

7 January 2021

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Hedonic sensitivity to low-dose ketamine is modulated by gonadal hormones in a sex-dependent manner

7 January 2021

1 reference

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Sex Differences in Effects of Ketamine on Behavior, Spine Density, and Synaptic Proteins in Socially Isolated Rats

7 January 2021

1 reference

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Sex differences in morphine analgesia: an experimental study in healthy volunteers

7 January 2021

1 reference

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Effects of age and gender on in vitro properties of human liver microsomal monooxygenases

7 January 2021

1 reference

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The Social Salience Hypothesis of Oxytocin.

7 January 2021

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Considering Sex as a Biological Variable Will Be Valuable for Neuroscience Research

7 January 2021

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Hypothalamic oxytocin mediates social buffering of the stress response

7 January 2021

1 reference

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Cross-talk among oxytocin and arginine-vasopressin receptors: Relevance for basic and clinical studies of the brain and periphery

7 January 2021

1 reference

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Oxytocin induces social communication by activating arginine-vasopressin V1a receptors and not oxytocin receptors.

7 January 2021

1 reference

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Hypothalamic vasopressin systems are more sensitive to the long term effects of social defeat in males versus females.

7 January 2021

1 reference

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Sex-Specific Effects of Stress on Oxytocin Neurons Correspond With Responses to Intranasal Oxytocin.

7 January 2021

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Effects of a ketamine metabolite on synaptic NMDAR function.

7 January 2021

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Repeated ketamine treatment induces sex-specific behavioral and neurochemical effects in mice

7 January 2021

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Social fear conditioning as an animal model of social anxiety disorder

7 January 2021

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Photoperiod reverses the effects of estrogens on male aggression via genomic and nongenomic pathways.

7 January 2021

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Sex differences in hormonal responses to social conflict in the monogamous California mouse

7 January 2021

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Role of kappa-opioid receptors in stress and anxiety-related behavior

7 January 2021

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Acute inhibition of kappa opioid receptors before stress blocks depression-like behaviors in California mice

7 January 2021

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Sex is a major determinant of CYP3A4 expression in human liver

7 January 2021

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A selective inhibitor of serotonin uptake: Lilly 110140, 3-(p-trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine

7 January 2021

1 reference

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Dissociated central and peripheral release of vasopressin, but not oxytocin, in response to repeated swim stress: new insights into the secretory capacities of peptidergic neurons

7 January 2021

1 reference

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Exposure to extrinsic stressors, social defeat or bisphenol A, eliminates sex differences in DNA methyltransferase expression in the amygdala

7 January 2021

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Activation of kappa opioid receptors in the dorsal raphe have sex dependent effects on social behavior in California mice

7 January 2021

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Sex, trauma, stress hormones and depression

7 January 2021

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NMDAR inhibition-independent antidepressant actions of ketamine metabolites.

7 January 2021

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A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression

7 January 2021

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5-Hydroxytryptamine-independent antidepressant actions of (R)-ketamine in a chronic social defeat stress model

7 January 2021

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Brain oxytocin in social fear conditioning and its extinction: involvement of the lateral septum

7 January 2021

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A new selective inhibitor for uptake of serotonin into synaptosomes of rat brain: 3-(p-trifluoromethylphenoxy). N-methyl-3-phenylpropylamine

7 January 2021

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12 December 2020

The antidepressant effects of 5-HT uptake inhibitors.

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12 December 2020

Sertraline: a new antidepressant

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12 December 2020

Estrogen replacement and response to fluoxetine in a multicenter geriatric depression trial. Fluoxetine Collaborative Study Group

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12 December 2020

Central oxytocin administration reduces stress-induced corticosterone release and anxiety behavior in rats

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12 December 2020

Sex is a major determinant of CYP3A4 expression in human liver

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12 December 2020

The role of serendipity in drug discovery

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12 December 2020

Inhibition of vasopressin V1a receptors in the medioventral bed nucleus of the stria terminalis has sex- and context-specific anxiogenic effects

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12 December 2020

Selective serotonin reuptake inhibitors versus placebo in patients with major depressive disorder. A systematic review with meta-analysis and Trial Sequential Analysis

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12 December 2020

Sex differences in the psychopharmacological treatment of depression

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12 December 2020

Depression Is the Leading Cause of Disability Around the World

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12 December 2020

A Precision Medicine Approach to Oxytocin Trials

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10.1016/J.YFRNE.2018.05.003

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29859882%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29859882%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

PubMed publication ID

29859882

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29859882%20AND%20SRC:MED&resulttype=core&format=json