(Q84921228)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19921751%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

Notch promotes radioresistance of glioma stem cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19921751%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19921751%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Justin D Lathia

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19921751%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Jeremy N Rich

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19921751%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Jialiang Wang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19921751%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Timothy P Wakeman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19921751%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Xiao-Fan Wang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19921751%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Rebekah R White

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19921751%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Bruce A Sullenger

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19921751%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

publication date

1 January 2010

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12 February 2020

1 reference

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12 February 2020

volume

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12 February 2020

issue

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12 February 2020

page(s)

17-28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19921751%20AND%20SRC:MED&resulttype=core&format=json

Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation

12 February 2020

cites work

1 reference

12 December 2020

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

1 reference

12 December 2020

Notch signals control the fate of immature progenitor cells in the intestine

1 reference

12 December 2020

Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells

1 reference

12 December 2020

Exploiting the PI3K/AKT pathway for cancer drug discovery

1 reference

12 December 2020

Activating Notch1 mutations in mouse models of T-ALL.

1 reference

12 December 2020

Survival signaling by Notch1: mammalian target of rapamycin (mTOR)-dependent inhibition of p53

1 reference

12 December 2020

Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

1 reference

12 December 2020

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

1 reference

12 December 2020

Endogenous beta-amyloid production in presenilin-deficient embryonic mouse fibroblasts

1 reference

12 December 2020

Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells

1 reference

12 December 2020

Notch1 functions as a tumor suppressor in mouse skin

1 reference

12 December 2020

Impaired notch signaling promotes de novo squamous cell carcinoma formation

1 reference

12 December 2020

The BCL-2 protein family: opposing activities that mediate cell death

1 reference

12 December 2020

PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo

1 reference

12 December 2020

Mcl-1 is a key regulator of apoptosis during CNS development and after DNA damage

1 reference

12 December 2020

Direct orthotopic transplantation of fresh surgical specimen preserves CD133+ tumor cells in clinically relevant mouse models of medulloblastoma and glioma.

1 reference

12 December 2020

Notch-1 regulates transcription of the epidermal growth factor receptor through p53.

1 reference

12 December 2020

Targeting cancer stem cells through L1CAM suppresses glioma growth

1 reference

12 December 2020

Substrate specificity of gamma-secretase and other intramembrane proteases

1 reference

12 December 2020

Phase 2 safety trial targeting amyloid beta production with a gamma-secretase inhibitor in Alzheimer disease

1 reference

12 December 2020

EWS-FLI1 suppresses NOTCH-activated p53 in Ewing's sarcoma

1 reference

12 December 2020

Notch tumor suppressor function

1 reference

12 December 2020

c-Myc is required for maintenance of glioma cancer stem cells

1 reference

12 December 2020

Brain cancer stem cells display preferential sensitivity to Akt inhibition

1 reference

12 December 2020

Ionizing radiation shifts the PAI-1/ID-1 balance and activates notch signaling in endothelial cells

1 reference

12 December 2020

Notch signalling in cancer stem cells.

1 reference

12 December 2020

Association of reactive oxygen species levels and radioresistance in cancer stem cells

1 reference

12 December 2020

Emerging role of Notch in stem cells and cancer

1 reference

12 December 2020

SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma

1 reference

12 December 2020

Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells

1 reference

12 December 2020

Inhibition of gamma-secretase induces G2/M arrest and triggers apoptosis in breast cancer cells

1 reference

12 December 2020

Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors

1 reference

12 December 2020

Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor

1 reference

12 December 2020

Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells

1 reference

12 December 2020

Notch signaling in stem cell systems

1 reference

12 December 2020

Gene expression profiles of AML derived stem cells; similarity to hematopoietic stem cells

1 reference

12 December 2020

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

1 reference

12 December 2020

Contribution of Notch signaling activation to human glioblastoma multiforme.

1 reference

12 December 2020

CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles

1 reference

12 December 2020

Notch signaling in development and cancer.

1 reference

12 December 2020

Mammary stem cells and breast cancer--role of Notch signalling.

1 reference

12 December 2020

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia

1 reference

12 December 2020

Bare rudiments of notch signaling: how receptor levels are regulated

1 reference

12 December 2020

Malignant astrocytic glioma: genetics, biology, and paths to treatment

1 reference

12 December 2020

Notch activation promotes cell proliferation and the formation of neural stem cell-like colonies in human glioma cells

1 reference

12 December 2020

The bHLH gene hes1 as a repressor of the neuronal commitment of CNS stem cells.

1 reference

12 December 2020

Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1.

1 reference

12 December 2020

MCL-1S, a splicing variant of the antiapoptotic BCL-2 family member MCL-1, encodes a proapoptotic protein possessing only the BH3 domain

1 reference

12 December 2020

Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma

1 reference

12 December 2020

Apoptosis resistance of MCF-7 breast carcinoma cells to ionizing radiation is independent of p53 and cell cycle control but caused by the lack of caspase-3 and a caffeine-inhibitable event

1 reference

12 December 2020

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

1 reference

12 December 2020

Current management of glioblastoma multiforme

1 reference

12 December 2020

Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis

1 reference

12 December 2020

A simple technique for quantitation of low levels of DNA damage in individual cells

1 reference

12 December 2020

Caspase-3-dependent cleavage of Bcl-2 promotes release of cytochrome c

1 reference

12 December 2020

The antiapoptotic gene mcl-1 is up-regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway through a transcription factor complex containing CREB

1 reference

12 December 2020

Notch1 and notch2 have opposite effects on embryonal brain tumor growth

1 reference

12 December 2020

The SmoA1 mouse model reveals that notch signaling is critical for the growth and survival of sonic hedgehog-induced medulloblastomas

1 reference

12 December 2020

Notch promotes survival of neural precursor cells via mechanisms distinct from those regulating neurogenesis.

1 reference

12 December 2020

Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells

1 reference

12 December 2020

Cell-cycle checkpoints and cancer

1 reference

12 December 2020

Identification of human brain tumour initiating cells

1 reference

12 December 2020

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

1 reference

12 December 2020

Caspase-3-like activity determines the type of cell death following ionizing radiation in MOLT-4 human leukaemia cells

1 reference

12 December 2020

1 reference

12 December 2020

Identification of a cancer stem cell in human brain tumors

1 reference

12 December 2020

Cancerous stem cells can arise from pediatric brain tumors

1 reference

12 December 2020

The Anti-apoptotic Effect of Notch-1 Requires p56 -dependent, Akt/PKB-mediated Signaling in T Cells

1 reference

12 December 2020

Notch signaling: control of cell communication and cell fate

1 reference

12 December 2020

Increased activity and involvement of caspase-3 in radiation-induced apoptosis in neural cells precursors from developing rat brain

1 reference

12 December 2020

Chronic treatment with the gamma-secretase inhibitor LY-411,575 inhibits beta-amyloid peptide production and alters lymphopoiesis and intestinal cell differentiation

1 reference

12 December 2020

Repair of radiation damage to DNA.

1 reference

12 December 2020

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

1 reference

12 December 2020

Primitive neural stem cells from the mammalian epiblast differentiate to definitive neural stem cells under the control of Notch signaling

1 reference

12 December 2020

Notch in mammary gland development and breast cancer

1 reference

12 December 2020

Identifiers

DOI

10.1002/STEM.261

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19921751%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

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12 February 2020

PubMed publication ID

19921751

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19921751%20AND%20SRC:MED&resulttype=core&format=json