(Q80168002)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17438574%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

review article

1 reference

title

New developments in FcepsilonRI regulation, function and inhibition (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17438574%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Stefan Kraft

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17438574%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Jean-Pierre Kinet

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17438574%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

publication date

1 May 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17438574%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Immunology

29 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17438574%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17438574%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17438574%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

page(s)

365-378

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17438574%20AND%20SRC:MED&resulttype=core&format=json

The high-affinity IgE receptor (Fc epsilon RI): from physiology to pathology

29 December 2019

cites work

1 reference

Glycosylation of human truncated Fc epsilon RI alpha chain is necessary for efficient folding in the endoplasmic reticulum

31 March 2020

1 reference

Structure of the human IgE-Fc C epsilon 3-C epsilon 4 reveals conformational flexibility in the antibody effector domains

31 March 2020

1 reference

The crystal structure of IgE Fc reveals an asymmetrically bent conformation

31 March 2020

1 reference

Mutagenesis within human FcepsilonRIalpha differentially affects human and murine IgE binding.

31 March 2020

1 reference

Crystal structure of the human high-affinity IgE receptor

31 March 2020

1 reference

Structure of the Fc fragment of human IgE bound to its high-affinity receptor Fc epsilonRI alpha

31 March 2020

1 reference

Human neutrophils express the high-affinity receptor for immunoglobulin E (Fc epsilon RI): role in asthma

31 March 2020

1 reference

Expression and functions of the high‐affinity IgE receptor on human platelets and megakaryocyte precursors

31 March 2020

1 reference

Cotranslational endoplasmic reticulum assembly of FcepsilonRI controls the formation of functional IgE-binding receptors

31 March 2020

1 reference

IL-4 induces the intracellular expression of the alpha chain of the high-affinity receptor for IgE in in vitro-generated dendritic cells

31 March 2020

1 reference

Evidence for a differential expression of the FcepsilonRIgamma chain in dendritic cells of atopic and nonatopic donors

31 March 2020

1 reference

Induction of the high-affinity IgE receptor (Fc epsilon RI) on human mast cells by IL-4

31 March 2020

1 reference

Regulation of the human Fc epsilon RI alpha-chain distal promoter

31 March 2020

1 reference

IgE receptors on human basophils. Relationship to serum IgE concentration

31 March 2020

1 reference

Expression of functional high affinity immunoglobulin E receptors (Fc epsilon RI) on monocytes of atopic individuals

31 March 2020

1 reference

Expression of high-affinity IgE receptors (FcϵRI) on peripheral blood basophils, monocytes, and eosinophils in atopic and nonatopic subjects: Relationship to total serum IgE concentrations

31 March 2020

1 reference

Surface expression of Fc epsilon RI on Langerhans' cells of clinically uninvolved skin is associated with disease activity in atopic dermatitis, allergic asthma, and rhinitis

31 March 2020

1 reference

Immunomorphological and ultrastructural characterization of Langerhans cells and a novel, inflammatory dendritic epidermal cell (IDEC) population in lesional skin of atopic eczema

31 March 2020

1 reference

Mast cells lacking the high affinity immunoglobulin E receptor are deficient in Fc epsilon RI gamma messenger RNA

31 March 2020

1 reference

Export of the high affinity IgE receptor from the endoplasmic reticulum depends on a glycosylation-mediated quality control mechanism

31 March 2020

1 reference

Expression of high-affinity binding of human immunoglobulin E by transfected cells

31 March 2020

1 reference

Complete structure and expression in transfected cells of high affinity IgE receptor

31 March 2020

1 reference

A second amplifier function for the allergy-associated Fc(epsilon)RI-beta subunit

31 March 2020

1 reference

Competing Functions Encoded in the Allergy-Associated FcϵRIβ Gene

31 March 2020

1 reference

Coordinate synthesis and degradation of the alpha-, beta- and gamma-subunits of the receptor for immunoglobulin E.

31 March 2020

1 reference

The receptor for immunoglobulin E on rat basophilic leukemia cells: effect of ligand binding on receptor expression

31 March 2020

1 reference

IgE enhances mouse mast cell Fc(epsilon)RI expression in vitro and in vivo: evidence for a novel amplification mechanism in IgE-dependent reactions

31 March 2020

1 reference

Minimal requirements for IgE-mediated regulation of surface Fc epsilon RI.

31 March 2020

1 reference

Roles of mast cells and basophils in innate and acquired immunity

31 March 2020

1 reference

Mast cells as sentinels of innate immunity

31 March 2020

1 reference

Recruitment of neutrophils during IgE-dependent cutaneous late phase reactions in the mouse is mast cell-dependent. Partial inhibition of the reaction with antiserum against tumor necrosis factor-alpha

31 March 2020

1 reference

Mast cells as "tunable" effector and immunoregulatory cells: recent advances.

31 March 2020

1 reference

Regulation of mast cell survival by IgE

31 March 2020

1 reference

Monomeric IgE stimulates signaling pathways in mast cells that lead to cytokine production and cell survival

31 March 2020

1 reference

Evidence that IgE molecules mediate a spectrum of effects on mast cell survival and activation via aggregation of the FcepsilonRI.

31 March 2020

1 reference

Antigen-independent induction of histamine synthesis by immunoglobulin E in mouse bone marrow-derived mast cells

31 March 2020

1 reference

Regulation of highly cytokinergic IgE-induced mast cell adhesion by Src, Syk, Tec, and protein kinase C family kinases

31 March 2020

1 reference

IgE- and IgE+Ag-mediated mast cell migration in an autocrine/paracrine fashion

31 March 2020

1 reference

Rapid and large amount of autocrine IL-3 production is responsible for mast cell survival by IgE in the absence of antigen

31 March 2020

1 reference

Early divergence of Fc epsilon receptor I signals for receptor up-regulation and internalization from degranulation, cytokine production, and survival

31 March 2020

1 reference

Monomeric IgE stimulates NFAT translocation into the nucleus, a rise in cytosol Ca2+, degranulation, and membrane ruffling in the cultured rat basophilic leukemia-2H3 mast cell line

31 March 2020

1 reference

Fc receptors as determinants of allergic reactions

31 March 2020

1 reference

Aggregation of the high-affinity IgE receptor Fc(epsilon)RI on human monocytes and dendritic cells induces NF-kappaB activation

31 March 2020

1 reference

Enhanced expression and activity of protein-tyrosine kinases establishes a functional signaling pathway only in FcepsilonRIhigh Langerhans cells from atopic individuals

31 March 2020

1 reference

Engagement of the Fc epsilon RI stimulates the production of IL-16 in Langerhans cell-like dendritic cells

31 March 2020

1 reference

FcepsilonRI engagement of Langerhans cell-like dendritic cells and inflammatory dendritic epidermal cell-like dendritic cells induces chemotactic signals and different T-cell phenotypes in vitro

31 March 2020

1 reference

A reducing microenvironment leads to the generation of FcepsilonRIhigh inflammatory dendritic epidermal cells (IDEC).

31 March 2020

1 reference

Characterization of FcepsilonRI-bearing CD123 blood dendritic cell antigen-2 plasmacytoid dendritic cells in atopic dermatitis

31 March 2020

1 reference

Analysis of the Cytokine Pattern Expressed In Situ in Inhalant Allergen Patch Test Reactions of Atopic Dermatitis Patients

31 March 2020

1 reference

TLR9- and FcepsilonRI-mediated responses oppose one another in plasmacytoid dendritic cells by down-regulating receptor expression.

31 March 2020

1 reference

Mast cells control neutrophil recruitment during T cell-mediated delayed-type hypersensitivity reactions through tumor necrosis factor and macrophage inflammatory protein 2.

31 March 2020

1 reference

Immune sensitization in the skin is enhanced by antigen-independent effects of IgE.

31 March 2020

1 reference

Mast cell-dependent migration of effector CD8+ T cells through production of leukotriene B4.

31 March 2020

1 reference

Mast cells induce T-cell adhesion to human fibroblasts by regulating intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 expression

31 March 2020

1 reference

Human dermal mast cells contain and release tumor necrosis factor alpha, which induces endothelial leukocyte adhesion molecule 1

31 March 2020

1 reference

Role of the high affinity immunoglobulin E receptor in bacterial translocation and intestinal inflammation

31 March 2020

1 reference

Signalling through the high-affinity IgE receptor Fc epsilonRI.

31 March 2020

1 reference

Molecular regulation of mast cell activation

31 March 2020

1 reference

Integrated signalling pathways for mast-cell activation

31 March 2020

1 reference

Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation

31 March 2020

1 reference

syk kinase activation by a src kinase-initiated activation loop phosphorylation chain reaction

31 March 2020

1 reference

LAT is essential for Fc(epsilon)RI-mediated mast cell activation

31 March 2020

1 reference

Redundant and opposing functions of two tyrosine kinases, Btk and Lyn, in mast cell activation

31 March 2020

1 reference

Btk/Tec kinases regulate sustained increases in intracellular Ca2+ following B-cell receptor activation

31 March 2020

1 reference

Phosphatidylinositol-3,4,5-trisphosphate (PtdIns-3,4,5-P3)/Tec kinase-dependent calcium signaling pathway: a target for SHIP-mediated inhibitory signals

31 March 2020

1 reference

Essential role for Gab2 in the allergic response

31 March 2020

1 reference

Transfection of Syk protein tyrosine kinase reconstitutes high affinity IgE receptor-mediated degranulation in a Syk-negative variant of rat basophilic leukemia RBL-2H3 cells

31 March 2020

1 reference

The Fc(epsilon)RIbeta subunit functions as an amplifier of Fc(epsilon)RIgamma-mediated cell activation signals

31 March 2020

1 reference

The FcepsilonRIbeta immunoreceptor tyrosine-based activation motif exerts inhibitory control on MAPK and IkappaB kinase phosphorylation and mast cell cytokine production

31 March 2020

1 reference

Molecular dissection of the FcRbeta signaling amplifier

31 March 2020

1 reference

Positive and negative regulation of mast cell activation by Lyn via the FcepsilonRI

31 March 2020

1 reference

Store depletion and calcium influx

31 March 2020

1 reference

CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry

31 March 2020

1 reference

A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

31 March 2020

1 reference

Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai

31 March 2020

1 reference

CRACM1 multimers form the ion-selective pore of the CRAC channel.

31 March 2020

1 reference

Orai1 is an essential pore subunit of the CRAC channel

31 March 2020

1 reference

Amplification of CRAC current by STIM1 and CRACM1 (Orai1)

31 March 2020

1 reference

The balance between sphingosine and sphingosine-1-phosphate is decisive for mast cell activation after Fc epsilon receptor I triggering

31 March 2020

1 reference

Transactivation of sphingosine-1-phosphate receptors by FcepsilonRI triggering is required for normal mast cell degranulation and chemotaxis

31 March 2020

1 reference

Calcium mobilization via sphingosine kinase in signalling by the Fc epsilon RI antigen receptor

31 March 2020

1 reference

Sphingosine kinases, sphingosine 1-phosphate, apoptosis and diseases

31 March 2020

1 reference

Antigen-induced Ca2+ mobilization in RBL-2H3 cells: role of I(1,4,5)P3 and S1P and necessity of I(1,4,5)P3 production

31 March 2020

1 reference

Dichotomy of Ca2+ signals triggered by different phospholipid pathways in antigen stimulation of human mast cells

31 March 2020

1 reference

The sphingosine kinase-sphingosine-1-phosphate axis is a determinant of mast cell function and anaphylaxis

31 March 2020

1 reference

Calcium release-activated calcium current (ICRAC) is a direct target for sphingosine

31 March 2020

1 reference

Early activation of sphingosine kinase in mast cells and recruitment to FcepsilonRI are mediated by its interaction with Lyn kinase

31 March 2020

1 reference

IgE-dependent activation of sphingosine kinases 1 and 2 and secretion of sphingosine 1-phosphate requires Fyn kinase and contributes to mast cell responses

31 March 2020

1 reference

RabGEF1 is a negative regulator of mast cell activation and skin inflammation

31 March 2020

1 reference

An essential role for RasGRP1 in mast cell function and IgE-mediated allergic response

31 March 2020

1 reference

NTAL phosphorylation is a pivotal link between the signaling cascades leading to human mast cell degranulation following Kit activation and Fc epsilon RI aggregation

31 March 2020

1 reference

Non-T cell activation linker (NTAL): a transmembrane adaptor protein involved in immunoreceptor signaling

31 March 2020

1 reference

Positive and negative regulation of FcepsilonRI-mediated signaling by the adaptor protein LAB/NTAL

31 March 2020

1 reference

Negative regulation of mast cell signaling and function by the adaptor LAB/NTAL.

31 March 2020

1 reference

Negative regulation of Fc epsilonRI-mediated signaling and mast cell function by the adaptor protein LAX

31 March 2020

1 reference

Akt-dependent cytokine production in mast cells

31 March 2020

1 reference

The Bcl10-Malt1 complex segregates Fc epsilon RI-mediated nuclear factor kappa B activation and cytokine production from mast cell degranulation

31 March 2020

1 reference

Differential Requirement for Malt1 in T and B Cell Antigen Receptor Signaling

31 March 2020

1 reference

Regulation of allergy by Fc receptors.

31 March 2020

1 reference

Inhibitory receptors and allergy

31 March 2020

1 reference

Roles of FcγRIIB in Nasal Eosinophilia and IgE Production in Murine Allergic Rhinitis

31 March 2020

1 reference

SHIP modulates immune receptor responses by regulating membrane association of Btk.

31 March 2020

1 reference

Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor Fc(gamma)RIIB.

31 March 2020

1 reference

Two distinct tyrosine-based motifs enable the inhibitory receptor FcgammaRIIB to cooperatively recruit the inositol phosphatases SHIP1/2 and the adapters Grb2/Grap

31 March 2020

1 reference

Co-aggregation of FcgammaRII with FcepsilonRI on human mast cells inhibits antigen-induced secretion and involves SHIP-Grb2-Dok complexes

31 March 2020

1 reference

The CD200 receptor is a novel and potent regulator of murine and human mast cell function

31 March 2020

1 reference

Negative Regulation of FcεRI-mediated Degranulation by CD81

31 March 2020

1 reference

Specific tetraspanin functions

31 March 2020

1 reference

31 March 2020

1 reference

Anti-CD63 antibodies suppress IgE-dependent allergic reactions in vitro and in vivo

31 March 2020

1 reference

Reconstitution of High Affinity IgE Receptor-mediated Secretion By Transfecting Protein Tyrosine Kinase pp125FAK

31 March 2020

1 reference

The anti-IgE antibody omalizumab reduces exacerbations and steroid requirement in allergic asthmatics

31 March 2020

1 reference

Anti-immunoglobulin E treatment with omalizumab in allergic diseases: an update on anti-inflammatory activity and clinical efficacy

31 March 2020

1 reference

Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma

31 March 2020

1 reference

Effect of omalizumab on symptoms of seasonal allergic rhinitis: a randomized controlled trial.

31 March 2020

1 reference

Effect of anti-IgE therapy in patients with peanut allergy

31 March 2020

1 reference

Effects of treatment with anti-immunoglobulin E antibody omalizumab on airway inflammation in allergic asthma

31 March 2020

1 reference

Omalizumab treatment downregulates dendritic cell FcepsilonRI expression

31 March 2020

1 reference

Apoptosis-inducing human-origin Fcepsilon-Bak chimeric proteins for targeted elimination of mast cells and basophils: a new approach for allergy treatment

31 March 2020

1 reference

IgG-blocking antibodies inhibit IgE-mediated anaphylaxis in vivo through both antigen interception and Fc gamma RIIb cross-linking

31 March 2020

1 reference

A bispecific antibody against human IgE and human FcgammaRII that inhibits antigen-induced histamine release by human mast cells and basophils

31 March 2020

1 reference

A novel human immunoglobulin Fc gamma Fc epsilon bifunctional fusion protein inhibits Fc epsilon RI-mediated degranulation

31 March 2020

1 reference

A new strategy to counter allergy

31 March 2020

1 reference

A chimeric human-cat fusion protein blocks cat-induced allergy

31 March 2020

1 reference

FcgammaRIIB Ile232Thr transmembrane polymorphism associated with human systemic lupus erythematosus decreases affinity to lipid rafts and attenuates inhibitory effects on B cell receptor signaling.

31 March 2020

1 reference

Mast cells in autoimmune disease

31 March 2020

1 reference

Distinct phosphoinositide 3-kinases mediate mast cell degranulation in response to G-protein-coupled versus FcepsilonRI receptors

31 March 2020

1 reference

Phosphoinositide 3-kinase gamma is an essential amplifier of mast cell function

31 March 2020

1 reference

Essential role for the p110delta phosphoinositide 3-kinase in the allergic response

31 March 2020

1 reference

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

31 March 2020

1 reference

gp49B1-alpha(v)beta3 interaction inhibits antigen-induced mast cell activation

31 March 2020

1 reference

Increased severity of local and systemic anaphylactic reactions in gp49B1-deficient mice

31 March 2020

1 reference

Impaired kit- but not FcepsilonRI-initiated mast cell activation in the absence of phosphoinositide 3-kinase p85alpha gene products.

31 March 2020

1 reference

Selective inhibition of the Fc epsilon RI-induced de novo synthesis of mediators by an inhibitory receptor.

31 March 2020

1 reference

A secretion inhibitory signal transduction molecule on mast cells is another C-type lectin.

31 March 2020

1 reference

Regulation of mast cells' secretory response by co-clustering the Type 1 Fcepsilon receptor with the mast cell function-associated antigen

31 March 2020

1 reference

Possible interactions between the Fcε receptor and a novel mast cell function-associated antigen

31 March 2020

1 reference

SH2 domain-containing inositol polyphosphate 5'-phosphatase is the main mediator of the inhibitory action of the mast cell function-associated antigen

31 March 2020

1 reference

A common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells

31 March 2020

1 reference

Signal regulatory proteins negatively regulate immunoreceptor-dependent cell activation.

31 March 2020

1 reference

The inhibitory receptor IRp60 (CD300a) is expressed and functional on human mast cells

31 March 2020

1 reference

Paired activating and inhibitory immunoglobulin-like receptors, MAIR-I and MAIR-II, regulate mast cell and macrophage activation

31 March 2020

1 reference

IREM-1 is a novel inhibitory receptor expressed by myeloid cells

31 March 2020

1 reference

The IREM-1 (CD300f) inhibitory receptor associates with the p85alpha subunit of phosphoinositide 3-kinase

31 March 2020

1 reference

Sphingosine 1-phosphate modulates human airway smooth muscle cell functions that promote inflammation and airway remodeling in asthma

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRI2072

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17438574%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17438574%20AND%20SRC:MED&resulttype=core&format=json