(Q79451353)

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Polymorphisms in vitamin K-dependent gamma-carboxylation-related genes influence interindividual variability in plasma protein C and protein S activities in the general population

scientific article published on 01 December 2006

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17189218%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

Polymorphisms in vitamin K-dependent gamma-carboxylation-related genes influence interindividual variability in plasma protein C and protein S activities in the general population (English)

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Europe PubMed Central

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23 December 2019

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Yoshihiro Kokubo

2

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Yoshihiro Kokubo

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Europe PubMed Central

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23 December 2019

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Rina Kimura

1

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23 December 2019

Kotaro Miyashita

3

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23 December 2019

Ryoichi Otsubo

4

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23 December 2019

Kazuyuki Nagatsuka

5

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23 December 2019

Toshiho Otsuki

6

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23 December 2019

Toshiyuki Sakata

7

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Europe PubMed Central

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23 December 2019

Junko Nagura

8

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17189218%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

Akira Okayama

9

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17189218%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

Kazuo Minematsu

10

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Europe PubMed Central

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23 December 2019

Hiroaki Naritomi

11

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Europe PubMed Central

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23 December 2019

Shigenori Honda

12

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23 December 2019

Kiyoshi Sato

13

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Europe PubMed Central

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23 December 2019

Hitonobu Tomoike

14

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Europe PubMed Central

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23 December 2019

Toshiyuki Miyata

15

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Europe PubMed Central

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23 December 2019

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1 December 2006

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Europe PubMed Central

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23 December 2019

International Journal of Hematology

1 reference

Europe PubMed Central

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23 December 2019

84

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23 December 2019

5

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23 December 2019

387-397

1 reference

Europe PubMed Central

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23 December 2019

An Alternative Fast and Convenient Genotyping Method for the Screening of Angiotensin Converting Enzyme Gene Polymorphisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

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Population variation in VKORC1 haplotype structure

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

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Potential of carotid enlargement as a useful indicator affected by high blood pressure in a large general population of a Japanese city: the Suita study

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

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VKORCI haplotypes and their impact on the inter-individual and inter-ethnical variability of oral anticoagulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

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A Quantitative Trait Locus Influencing Free Plasma Protein S Levels on Human Chromosome 1q

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

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A conserved region of human vitamin K-dependent carboxylase between residues 393 and 404 is important for its interaction with the glutamate substrate

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

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Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

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Engineering of a recombinant vitamin K-dependent gamma-carboxylation system with enhanced gamma-carboxyglutamic acid forming capacity: evidence for a functional CXXC redox center in the system

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular basis of vitamin K-dependent gamma-carboxylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

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Different contributions of polymorphisms in VKORC1 and CYP2C9 to intra- and inter-population differences in maintenance dose of warfarin in Japanese, Caucasians and African-Americans

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

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Recommendations for a nomenclature system for human gene mutations. Nomenclature Working Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of disulfide bond assignment of human vitamin K-dependent gamma-glutamyl carboxylase by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

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A novel functional VKORC1 promoter polymorphism is associated with inter-individual and inter-ethnic differences in warfarin sensitivity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gamma-carboxyglutamate-containing proteins and the vitamin K-dependent carboxylase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A polymorphism in the VKORC1 gene is associated with an interindividual variability in the dose-anticoagulant effect of warfarin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

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Protein C levels are regulated by a quantitative trait locus on chromosome 16: results from the Genetic Analysis of Idiopathic Thrombophilia (GAIT) Project

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of sequences within the gamma-carboxylase that represent a novel contact site with vitamin K-dependent proteins and that are required for activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

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Inflammation and thrombosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane topology mapping of vitamin K epoxide reductase by in vitro translation/cotranslocation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and Expression of the cDNA for Human γ-glutamyl Carboxylase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitamin K 2,3-epoxide reductase and the vitamin K-dependent gamma-carboxylation system

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein C and antithrombin deficiency are important risk factors for deep vein thrombosis in Japanese

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome scan of venous thrombosis in a pedigree with protein C deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of 108 SNPs in TSC, WNK1, and WNK4 and their association with hypertension in a Japanese general population

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein C activity in healthy volunteers--influence of age, sex, smoking and oral contraceptives

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Verification of 525 coding SNPs in 179 hypertension candidate genes in the Japanese population: identification of 159 SNPs in 93 genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inhibitory effect of calumenin on the vitamin K-dependent gamma-carboxylation system. Characterization of the system in normal and warfarin-resistant rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the vitamin K-dependent carboxylase active site: Cys-99 and Cys-450 are required for both epoxidation and carboxylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A topological study of the human gamma-glutamyl carboxylase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genotypic variation in the promoter region of the protein C gene is associated with plasma protein C levels and thrombotic risk

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A molecular mechanism for genetic warfarin resistance in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma levels of protein S, protein C, and factor X: effects of sex, hormonal state and age.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of VKORC1 and CYP2C9 polymorphisms with warfarin dose requirements in Japanese patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calumenin, a Ca2+-binding Protein Retained in the Endoplasmic Reticulum with a Novel Carboxyl-terminal Sequence, HDEF

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The impact of CYP2C9 and VKORC1 genetic polymorphism and patient characteristics upon warfarin dose requirements: proposal for a new dosing regimen

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The vitamin K cycle.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complex association of protein C gene promoter polymorphism with circulating protein C levels and thrombotic risk

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of blood coagulation by the protein C anticoagulant pathway: novel insights into structure-function relationships and molecular recognition

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic risk factors for deep vein thrombosis among Japanese: importance of protein S K196E mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevalence of protein S deficiency in the Japanese general population: the Suita Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic regulation of plasma levels of vitamin K-dependent proteins involved in hematostatis: results from the GAIT Project. Genetic Analysis of Idiopathic Thrombophilia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase (VKORC1) genotypes as determinants of acenocoumarol sensitivity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitamin K-dependent biosynthesis of gamma-carboxyglutamic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Common VKORC1 and GGCX polymorphisms associated with warfarin dose

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the gene for vitamin K epoxide reductase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17189218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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