(Q79314029)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14630925%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

title

Heparanase degrades syndecan-1 and perlecan heparan sulfate: functional implications for tumor cell invasion (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14630925%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Jane Reiland

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14630925%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Ralph D Sanderson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14630925%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Marian Waguespack

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14630925%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Steven A Barker

1 reference

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21 December 2019

Robert Long

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14630925%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Daniel D Carson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14630925%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Dario Marchetti

1 reference

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21 December 2019

language of work or name

English

0 references

publication date

20 November 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14630925%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

21 December 2019

published in

1 reference

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21 December 2019

volume

279

1 reference

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21 December 2019

issue

1 reference

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21 December 2019

page(s)

8047-8055

1 reference

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Functions of cell surface heparan sulfate proteoglycans

21 December 2019

cites work

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Matrix proteoglycans: from molecular design to cellular function

21 January 2018

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Heparan sulfate proteoglycans: intricate molecules with intriguing functions.

21 January 2018

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In the clutches of proteoglycans: how does heparan sulfate regulate FGF binding?

21 January 2018

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Heparan sulfate proteoglycans in invasion and metastasis

21 January 2018

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The cell surface proteoglycan syndecan-1 mediates fibroblast growth factor-2 binding and activity

21 January 2018

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Proteoglycans: structures and interactions

21 January 2018

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Regulation of growth factor activation by proteoglycans: what is the role of the low affinity receptors?

21 January 2018

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Heparan sulphate: functional role as a modulator of fibroblast growth factor activity

21 January 2018

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Role of heparan sulfate proteoglycans in the uptake and degradation of tissue factor pathway inhibitor-coagulation factor Xa complexes

21 January 2018

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Endothelial cell heparanase modulation of lipoprotein lipase activity. Evidence that heparan sulfate oligosaccharide is an extracellular chaperone

21 January 2018

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Inhibition of DNA topoisomerase I activity by heparan sulfate and modulation by basic fibroblast growth factor.

21 January 2018

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Heparanases and tumor metastasis

21 January 2018

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Enzymatic degradation of glycosaminoglycans

21 January 2018

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Expression in Escherichia coli, purification and characterization of heparinase I from Flavobacterium heparinum

21 January 2018

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Nerve growth factor effects on human and mouse melanoma cell invasion and heparanase production

21 January 2018

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Human heparanase: a molecular determinant of brain metastasis

21 January 2018

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Human heparanase. Purification, characterization, cloning, and expression

21 January 2018

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Tumor cell surface heparan sulfate as cryptic promoters or inhibitors of tumor growth and metastasis

21 January 2018

1 reference

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Elevated levels of shed syndecan-1 correlate with tumour mass and decreased matrix metalloproteinase-9 activity in the serum of patients with multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304872200

Soluble syndecan-1 promotes growth of myeloma tumors in vivo

21 January 2018

1 reference

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The biology of perlecan: the multifaceted heparan sulphate proteoglycan of basement membranes and pericellular matrices

21 January 2018

1 reference

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Antisense targeting of perlecan blocks tumor growth and angiogenesis in vivo

21 January 2018

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Suppression of invasive behavior of melanoma cells by stable expression of anti-sense perlecan cDNA.

21 January 2018

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Cell surface expression and secretion of heparanase markedly promote tumor angiogenesis and metastasis

21 January 2018

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Mammalian heparanase: gene cloning, expression and function in tumor progression and metastasis

21 January 2018

1 reference

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Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304872200

Cloning and functional expression of a human heparanase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304872200

Human heparanase is localized within lysosomes in a stable form

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304872200

Inhibition of heparanase activity and heparanase-induced angiogenesis by suramin analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304872200

Electrophoretic, biosensor, and bioactivity analyses of perlecans of different cellular origins.

21 January 2018

1 reference

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Biosynthesis of heparan sulfate proteoglycan by human colon carcinoma cells and its localization at the cell surface

21 January 2018

1 reference

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Direct isolation and sequencing of specific protein-binding glycosaminoglycans

21 January 2018

1 reference

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Neurotrophin stimulation of human melanoma cell invasion: Selected enhancement of heparanase activity and heparanase degradation of specific heparan sulfate subpopulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304872200

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

1 reference

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Human platelet heparanase: purification, characterization and catalytic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304872200

Heparan sulfate regulates targeting of syndecan-1 to a functional domain on the cell surface

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304872200

Syndecan-1, a cell-surface proteoglycan, changes in size and abundance when keratinocytes stratify

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304872200

Self-association of N-Syndecan (Syndecan-3) Core Protein Is Mediated by a Novel Structural Motif in the Transmembrane Domain and Ectodomain Flanking Region

21 January 2018

1 reference

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A rapid quantitative assay for the detection of mammalian heparanase activity

21 January 2018

1 reference

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Structural recognition by recombinant human heparanase that plays critical roles in tumor metastasis. Hierarchical sulfate groups with different effects and the essential target disulfated trisaccharide sequence

21 January 2018

1 reference

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Heparan sulfate-like proteoglycans mediate adhesion of human malignant melanoma A375 cells to P-selectin under flow

21 January 2018

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Substrate specificity of heparanases from human hepatoma and platelets

21 January 2018

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Heparin/Heparan sulfate domains in binding and signaling of fibroblast growth factor 8b.

21 January 2018

1 reference

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Intracerebral tumor-associated hemorrhage caused by overexpression of the vascular endothelial growth factor isoforms VEGF 121 and VEGF 165 but not VEGF 189

21 January 2018

1 reference

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Syndecan-regulated receptor signaling

21 January 2018

1 reference

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Heparanase and platelet factor-4 induce smooth muscle cell proliferation and migration via bFGF release from the ECM

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304872200

Physiological degradation converts the soluble syndecan-1 ectodomain from an inhibitor to a potent activator of FGF-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304872200

Specific degradation of subendothelial matrix proteoglycans by brain-metastatic melanoma and brain endothelial cell heparanases

21 January 2018

1 reference

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Regulated diversity of heparan sulfate

21 January 2018

1 reference

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Cytoplasmic interactions of syndecan-4 orchestrate adhesion receptor and growth factor receptor signalling

21 January 2018

1 reference

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Heparan sulfate chains from glypican and syndecans bind the Hep II domain of fibronectin similarly despite minor structural differences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304872200

21 January 2018

Identifiers

DOI

10.1074/JBC.M304872200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14630925%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14630925%20AND%20SRC:MED&resulttype=core&format=json