(Q77917222)

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Phosphorylation and coupling of zeta-chains to activated T-cell receptor (TCR)/CD3 complexes from peripheral blood T-cells of elderly humans

scientific article published on 01 September 1998

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9 December 2019

Phosphorylation and coupling of zeta-chains to activated T-cell receptor (TCR)/CD3 complexes from peripheral blood T-cells of elderly humans (English)

1 reference

Europe PubMed Central

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9 December 2019

author name string

R L Whisler

1

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9 December 2019

C I Karanfilov

2

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9 December 2019

Y G Newhouse

3

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9 December 2019

C C Fox

4

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9 December 2019

R R Lakshmanan

5

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9 December 2019

B Liu

6

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9 December 2019

publication date

1 September 1998

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9 December 2019

Mechanisms of Ageing and Development

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9922123%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

105

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9 December 2019

1-2

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9 December 2019

115-135

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9922123%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex

1 reference

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7 January 2021

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Immune senescence: mechanisms and clinical implications

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7 January 2021

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Molecular associations between the T-lymphocyte antigen receptor complex and the surface antigens CD2, CD4, or CD8 and CD5

1 reference

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7 January 2021

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The CD45 tyrosine phosphatase regulates specific pools of antigen receptor-associated p59fyn and CD4-associated p56lck tyrosine in human T-cells.

1 reference

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7 January 2021

based on heuristic

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The zeta chain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation associates with ZAP-70, a 70-kDa tyrosine phosphoprotein

1 reference

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7 January 2021

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The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction

1 reference

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7 January 2021

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Regulation of T cell receptor signaling by a src family protein-tyrosine kinase (p59fyn).

1 reference

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7 January 2021

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Loss of CD28 expression on T lymphocytes: a marker of replicative senescence

1 reference

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7 January 2021

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Decline in CD28+ T cells in centenarians and in long-term T cell cultures: a possible cause for both in vivo and in vitro immunosenescence

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2898%2900084-0

7 January 2021

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Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2898%2900084-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Signalling by receptor tyrosine kinases

1 reference

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7 January 2021

based on heuristic

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Memory T lymphocyte hyporesponsiveness to non-cognate stimuli: a key factor in age-related immunodeficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2898%2900084-0

7 January 2021

based on heuristic

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Differential tyrosine phosphorylation of zeta chain dimers in mouse CD4 T lymphocytes: effect of age

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2898%2900084-0

7 January 2021

based on heuristic

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Absence of ZAP-70 prevents signaling through the antigen receptor on peripheral blood T cells but not on thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2898%2900084-0

7 January 2021

based on heuristic

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Rapid tyrosine phosphorylation of Grb2 and Shc in T cells exposed to anti-CD3, anti-CD4, and anti-CD45 stimuli: differential effects of aging

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2898%2900084-0

7 January 2021

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Immunological studies of aging. Decreased production of and response to T cell growth factor by lymphocytes from aged humans

1 reference

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7 January 2021

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Molecular alterations in the aging immune system

1 reference

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7 January 2021

based on heuristic

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Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases

1 reference

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7 January 2021

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

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7 January 2021

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Pgp-1hi T lymphocytes accumulate with age in mice and respond poorly to concanavalin A.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2898%2900084-0

7 January 2021

based on heuristic

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Distinct intracellular localization of Lck and Fyn protein tyrosine kinases in human T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2898%2900084-0

7 January 2021

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Admission criteria for immunogerontological studies in man: the SENIEUR protocol

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2898%2900084-0

7 January 2021

based on heuristic

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Antigen-independent changes in naive CD4 T cells with aging

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2898%2900084-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2898%2900084-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunologic response in an elderly population with a mean age of 85

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2898%2900084-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Decreased proliferation, interleukin 2 synthesis, and interleukin 2 receptor expression are accompanied by decreased mRNA expression in phytohemagglutinin-stimulated cells from elderly donors

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2898%2900084-0

7 January 2021

based on heuristic

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Age-associated changes in mitogen-induced protein phosphorylation in murine T lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2898%2900084-0

7 January 2021

based on heuristic

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Clonal populations of T cells in normal elderly humans: the T cell equivalent to "benign monoclonal gammapathy".

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2898%2900084-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Age-related tyrosine-specific protein phosphorylation defect in human T lymphocytes activated through CD3, CD4, CD8 or the IL-2 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2898%2900084-0

7 January 2021

based on heuristic

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Immunodeficiency of the elderly.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2898%2900084-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of the T cell antigen receptor--p60fyn protein tyrosine kinase association by chemical cross-linking

1 reference

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7 January 2021

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Tyrosine-specific protein phosphorylation in response to anti-CD3 antibody is diminished in old mice

1 reference

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7 January 2021

based on heuristic

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Partial T cell signaling: altered phospho-zeta and lack of zap70 recruitment in APL-induced T cell anergy

1 reference

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Age-related effects in T cell activation and proliferation

1 reference

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7 January 2021

based on heuristic

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SH2 domain function is essential for the role of the Lck tyrosine kinase in T cell receptor signal transduction

1 reference

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LckBP1, a proline-rich protein expressed in haematopoietic lineage cells, directly associates with the SH3 domain of protein tyrosine kinase p56lck

1 reference

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Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs

1 reference

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Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes

1 reference

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Cell-mediated immunity as a predictor of morbidity and mortality in subjects over 60

1 reference

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Age-related decreases in IL-2 production by human T cells are associated with impaired activation of nuclear transcriptional factors AP-1 and NF-AT

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Age-related reductions in the activation of mitogen-activated protein kinases p44mapk/ERK1 and p42mapk/ERK2 in human T cells stimulated via ligation of the T cell receptor complex

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Expression and catalytic activities of protein tyrosine kinases (PTKs) Fyn and Lck in peripheral blood T cells from elderly humans stimulated through the T cell receptor (TCR)/CD3 complex

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2898%2900084-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Impaired induction of c-fos/c-jun genes and of transcriptional regulatory proteins binding distinct c-fos/c-jun promoter elements in activated human T cells during aging

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

"Panning" for lymphocytes: a method for cell selection

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The kinase, SH3, and SH2 domains of Lck play critical roles in T-cell activation after ZAP-70 membrane localization

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2898%2900084-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Aging and immune function

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0047-6374(98)00084-0

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9922123%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9922123%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

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