(Q77060987)

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Phase II trial with ISIS 5132 in patients with small-cell (SCLC) and non-small cell (NSCLC) lung cancer. A European Organization for Research and Treatment of Cancer (EORTC) Early Clinical Studies Group report

scientific article published on 01 November 2001

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2 December 2019

Phase II trial with ISIS 5132 in patients with small-cell (SCLC) and non-small cell (NSCLC) lung cancer. A European Organization for Research and Treatment of Cancer (EORTC) Early Clinical Studies Group report (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11677106%20AND%20SRC:MED&resulttype=core&format=json

2 December 2019

phase II clinical trial

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1

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2 December 2019

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A Anthoney

2

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2 December 2019

W Fiedler

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2 December 2019

J P Droz

4

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2 December 2019

V Dieras

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2 December 2019

M Borner

6

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2 December 2019

J F Smyth

7

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2 December 2019

R Morant

8

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2 December 2019

M J de Vries

9

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2 December 2019

M Roelvink

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2 December 2019

P Fumoleau

11

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2 December 2019

European Organization for Research and Treatment of Cancer (EORTC)

12

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Europe PubMed Central

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2 December 2019

publication date

1 November 2001

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2 December 2019

European Journal of Cancer

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2 December 2019

37

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2 December 2019

17

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2 December 2019

2194-2198

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2 December 2019

The ins and outs of Raf kinases

1 reference

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Activation of human raf transforming genes by deletion of normal amino-terminal coding sequences

1 reference

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Transforming activity of human tumor DNAs

1 reference

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Interaction of the protein kinase Raf-1 with 14-3-3 proteins

1 reference

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7 January 2021

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Oncogene activation: c-raf-1 gene mutations in experimental and naturally occurring tumors

1 reference

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Bcl-2 targets the protein kinase Raf-1 to mitochondria

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7 January 2021

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Protein kinase C alpha activates RAF-1 by direct phosphorylation

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Sequence-specific antitumor activity of a phosphorothioate oligodeoxyribonucleotide targeted to human C-raf kinase supports an antisense mechanism of action in vivo

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Phase I clinical/pharmacokinetic and pharmacodynamic trial of the c-raf-1 antisense oligonucleotide ISIS 5132 (CGP 69846A).

1 reference

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Reporting results of cancer treatment

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Comprehensive criteria for assessing therapy-induced toxicity

1 reference

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7 January 2021

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Identifiers

10.1016/S0959-8049(01)00286-6

1 reference

Europe PubMed Central

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2 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11677106%20AND%20SRC:MED&resulttype=core&format=json

2 December 2019

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