(Q74005583)

English

Novel imidazolyl and triazolyl substituted biphenyl compounds: synthesis and evaluation as nonsteroidal inhibitors of human 17alpha-hydroxylase-C17, 20-lyase (P450 17)

scientific article published on 01 June 2000

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10896104%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Novel imidazolyl and triazolyl substituted biphenyl compounds: synthesis and evaluation as nonsteroidal inhibitors of human 17alpha-hydroxylase-C17, 20-lyase (P450 17) (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10896104%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

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Y Zhuang

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10896104%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

B G Wachall

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10896104%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

R W Hartmann

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10896104%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

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1 June 2000

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Europe PubMed Central

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8 November 2019

Bioorganic & Medicinal Chemistry

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10896104%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

8

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10896104%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

6

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10896104%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

1245-1252

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10896104%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

4,5-Dihydro-3-(2-pyrazinyl)naphtho[1,2-c]pyrazole: a potent and selective inhibitor of steroid-17 alpha-hydroxylase-C17,20-lyase (P450 17)

1 reference

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Inhibitors of enzymes of androgen biosynthesis: cytochrome P450(17) alpha and 5 alpha-steroid reductase

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Microsomal cytochrome P-450 from neonatal pig testis: two enzymatic activities (17 alpha-hydroxylase and c17,20-lyase) associated with one protein

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Cytochrome P-450 C21scc: one enzyme with two actions: hydroxylase and lyase

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Tetrahydronaphthalenes: influence of heterocyclic substituents on inhibition of steroid enzymes P450 arom and P450 17

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Synthesis and evaluation of azole-substituted tetrahydronaphthalenes as inhibitors of P450 arom, P450 17, and P450 TxA2

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17-Imidazolyl, Pyrazolyl, and Isoxazolyl Androstene Derivatives. Novel Steroidal Inhibitors of Human Cytochrome Cl7,20-Lyase (P45017α)

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Novel 17-azolyl steroids, potent inhibitors of human cytochrome 17 alpha-hydroxylase-C17,20-lyase (P450(17) alpha): potential agents for the treatment of prostate cancer.

1 reference

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7 January 2021

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Imidazole substituted biphenyls: a new class of highly potent and in vivo active inhibitors of P450 17 as potential therapeutics for treatment of prostate cancer

1 reference

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7 January 2021

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Synthesis and in vitro evaluation of 3-(1-azolylmethyl)-1H-indoles and 3-(1-azolyl-1-phenylmethyl)-1H-indoles as inhibitors of P450 arom

1 reference

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7 January 2021

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Pyridyl substituted benzocycloalkenes: new inhibitors of 17 alpha-hydroxylase/17,20-lyase (P450 17 alpha)

1 reference

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7 January 2021

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Pharmacology of novel steroidal inhibitors of cytochrome P450(17) alpha (17 alpha-hydroxylase/C17-20 lyase).

1 reference

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7 January 2021

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Aromatase inhibitors. Synthesis and evaluation of mammary tumor inhibiting activity of 3-alkylated 3-(4-aminophenyl)piperidine-2,6-diones

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Conformational analysis. 130. MM2. A hydrocarbon force field utilizing V1 and V2 torsional terms

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Identifiers

10.1016/S0968-0896(00)00076-6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10896104%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10896104%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

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