(Q73133824)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10542281%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

title

Recombinant human aggrecan G1-G2 exhibits native binding properties and substrate specificity for matrix metalloproteinases and aggrecanase (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10542281%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10542281%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10542281%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10542281%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

K J Doege

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10542281%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

E C Arner

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10542281%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

M A Pratta

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10542281%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

language of work or name

English

0 references

publication date

1 November 1999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10542281%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

1 November 2019

published in

1 reference

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1 November 2019

volume

274

1 reference

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1 November 2019

issue

1 reference

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1 November 2019

page(s)

32387-32395

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10542281%20AND%20SRC:MED&resulttype=core&format=json

Articular cartilage cultured with interleukin 1. Increased release of link protein, hyaluronate-binding region and other proteoglycan fragments

1 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Turnover of proteoglycans in articular-cartilage cultures. Characterization of proteoglycans released into the medium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

The immunologic detection and characterization of cartilage proteoglycan degradation products in synovial fluids of patients with arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Mechanism of catabolism of aggrecan by articular cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

N-terminal sequence of proteoglycan fragments isolated from medium of interleukin-1-treated articular-cartilage cultures. Putative site(s) of enzymic cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

The structure of aggrecan fragments in human synovial fluid. Evidence that aggrecanase mediates cartilage degradation in inflammatory joint disease, joint injury, and osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

VDIPEN, a metalloproteinase-generated neoepitope, is induced and immunolocalized in articular cartilage during inflammatory arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Aggrecan is degraded by matrix metalloproteinases in human arthritis. Evidence that matrix metalloproteinase and aggrecanase activities can be independent

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Aggrecan degradation in human cartilage. Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Aggrecan degradation in human intervertebral disc and articular cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Fibroblast and neutrophil collagenases cleave at two sites in the cartilage aggrecan interglobular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Degradation of cartilage aggrecan by collagenase-3 (MMP-13)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Membrane-type 1 MMP (MMP-14) cleaves at three sites in the aggrecan interglobular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Neutrophil collagenase (MMP-8) cleaves at the aggrecanase site E373-A374 in the interglobular domain of cartilage aggrecan

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Cleavage of native cartilage aggrecan by neutrophil collagenase (MMP-8) is distinct from endogenous cleavage by aggrecanase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

The Interglobular Domain of Cartilage Aggrecan Is Cleaved by Hemorrhagic Metalloproteinase HT-d (Atrolysin C) at the Matrix Metalloproteinase and Aggrecanase Sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Monoclonal antibodies that specifically recognize neoepitope sequences generated by 'aggrecanase' and matrix metalloproteinase cleavage of aggrecan: application to catabolism in situ and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Cell-mediated catabolism of aggrecan. Evidence that cleavage at the "aggrecanase" site (Glu373-Ala374) is a primary event in proteolysis of the interglobular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Development of a cleavage-site-specific monoclonal antibody for detecting metalloproteinase-derived aggrecan fragments: detection of fragments in human synovial fluids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Quantification of a matrix metalloproteinase-generated aggrecan G1 fragment using monospecific anti-peptide serum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Differential Expression of Aggrecanase and Matrix Metalloproteinase Activity in Chondrocytes Isolated from Bovine and Porcine Articular Cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Purification of recombinant human prostromelysin. Studies on heat activation to give high-Mr and low-Mr active forms, and a comparison of recombinant with natural stromelysin activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Matrix metalloproteinase degradation of elastin, type IV collagen and proteoglycan. A quantitative comparison of the activities of 95 kDa and 72 kDa gelatinases, stromelysins-1 and -2 and punctuated metalloproteinase (PUMP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

The purification of tissue inhibitor of metalloproteinases-2 from its 72 kDa progelatinase complex. Demonstration of the biochemical similarities of tissue inhibitor of metalloproteinases-2 and tissue inhibitor of metalloproteinases-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Biochemical characterization of human collagenase-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Hemorrhagic toxins from western diamondback rattlesnake (Crotalus atrox) venom: isolation and characterization of five toxins and the role of zinc in hemorrhagic toxin e

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Characteristics of the core protein of the aggregating proteoglycan from the Swarm rat chondrosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Isolation of the N-terminal globular protein domains from cartilage proteoglycans. Identification of G2 domain and its lack of interaction with hyaluronate and link protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Generation and characterization of aggrecanase. A soluble, cartilage-derived aggrecan-degrading activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

1-C-6 epitope in cartilage proteoglycan G2 domain is masked by keratan sulphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

The antigenic determinants recognized by three monoclonal antibodies to keratan sulphate involve sulphated hepta- or larger oligosaccharides of the poly(N-acetyllactosamine) series

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Structure of the human aggrecan gene: exon-intron organization and association with the protein domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Extended and globular protein domains in cartilage proteoglycans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Structure and interactions of cartilage proteoglycan binding region and link protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

The new collagenase, collagenase-3, is expressed and synthesized by human chondrocytes but not by synoviocytes. A role in osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Utilization of a Recombinant Substrate rAgg1 to Study the Biochemical Properties of Aggrecanase in Cell Culture Systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Identification of Hyaluronan-binding Domains of Aggrecan

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Hyaluronan-binding region of aggrecan from pig laryngeal cartilage. Amino acid sequence, analysis of N-linked oligosaccharides and location of the keratan sulphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Catabolism of aggrecan by explant cultures of human articular cartilage in the presence of retinoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

The production and purification of functional decorin in a baculovirus system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

N- and O-Linked Keratan Sulfate on the Hyaluronan Binding Region of Aggrecan from Mature and Immature Bovine Cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Biosynthesis and secretion of human interleukin 2 glycoprotein variants from baculovirus-infected Sf21 cells. Characterization of polypeptides and posttranslational modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Comparison of oligosaccharide processing among various insect cell lines expressing a secreted glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Intrinsic glycosylation potentials of insect cell cultures and insect larvae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Biochemical analysis of the N-glycosylation pathway in baculovirus-infected lepidopteran insect cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Microheterogeneity of the oligosaccharides carried by the recombinant bovine lactoferrin expressed in Mamestra brassicae cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Structural analysis and localization of the carbohydrate moieties of a soluble human interferon gamma receptor produced in baculovirus-infected insect cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Site-specific N-glycosylation and oligosaccharide structures of recombinant HIV-1 gp120 derived from a baculovirus expression system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Expression of bovine leukemia virus ENV glycoprotein in insect cells by recombinant baculovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

The role of N-glycosylation of human thromboxane A2 receptor in ligand binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

The influence of the nature of the asparagine 289-linked oligosaccharide on the activation by urokinase and lysine binding properties of natural and recombinant human plasminogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

Distinct secondary structures of the leucine-rich repeat proteoglycans decorin and biglycan. Glycosylation-dependent conformational stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32387

21 January 2018

Identifiers

DOI

10.1074/JBC.274.45.32387

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10542281%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10542281%20AND%20SRC:MED&resulttype=core&format=json