(Q73157282)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10551820%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

title

IkappaB kinases alpha and beta show a random sequential kinetic mechanism and are inhibited by staurosporine and quercetin (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10551820%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

G W Peet

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10551820%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

J Li

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10551820%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

language of work or name

English

0 references

publication date

1 November 1999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10551820%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

1 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10551820%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

volume

274

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10551820%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10551820%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

page(s)

32655-32661

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10551820%20AND%20SRC:MED&resulttype=core&format=json

The NF-kappa B and I kappa B proteins: new discoveries and insights

1 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

Identification and characterization of an IkappaB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

Limb and skin abnormalities in mice lacking IKKalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

IKK1-deficient mice exhibit abnormal development of skin and skeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

Biochemistry of natural pigments; (exclusive of haeme pigments and carotenoids)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

Protein tyrosine kinase inhibitors block tumor necrosis factor-induced activation of nuclear factor-kappaB, degradation of IkappaBalpha, nuclear translocation of p65, and subsequent gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

A new alkaloid AM-2282 OF Streptomyces origin. Taxonomy, fermentation, isolation and preliminary characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

Staurosporine, K-252 and UCN-01: potent but nonspecific inhibitors of protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

Pharmacologic modulation of acute ocular inflammation with quercetin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

Antiinflammatory effects of NADPH oxidase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

Role of IKK1 and IKK2 in lipopolysaccharide signaling in human monocytic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

Inhibition of NF-kappa B by sodium salicylate and aspirin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

Recombinant IkappaB kinases alpha and beta are direct kinases of Ikappa Balpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

The multisubunit IkappaB kinase complex shows random sequential kinetics and is activated by the C-terminal domain of IkappaB alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

Adenosine cyclic 3',5'-monophosphate dependent protein kinase: a new fluorescence displacement titration technique for characterizing the nucleotide binding site on the catalytic subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

Kinetic Mechanism for p38 MAP Kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

Synthesis and evaluation of multisubstrate inhibitors of an oncogene-encoded tyrosine-specific protein kinase. 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

Synthesis and evaluation of multisubstrate inhibitors of an oncogene-encoded tyrosine-specific protein kinase. 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

Structure-Based Design of a Potent, Selective, and Irreversible Inhibitor of the Catalytic Domain of the erbB Receptor Subfamily of Protein Tyrosine Kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

Effect of protein kinase inhibitors on activity of mammalian small heat-shock protein (HSP25) kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

A derivative of staurosporine (CGP 41 251) shows selectivity for protein kinase C inhibition and in vitro anti-proliferative as well as in vivo anti-tumor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

The effect of quercetin on the phosphorylatio activity of the Rous sarcoma virus transforming gene product in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

Different properties of monomer and heterodimer forms of phosphatidylinositol 3-kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32655

21 January 2018

Identifiers

DOI

10.1074/JBC.274.46.32655

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10551820%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10551820%20AND%20SRC:MED&resulttype=core&format=json