(Q64066124)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30898137%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

title

Trabectedin triggers direct and NK-mediated cytotoxicity in multiple myeloma (English)

1 reference

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30 April 2020

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0 references

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30 April 2020

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30 April 2020

1 reference

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30 April 2020

Pierfrancesco Tassone

object named as

Pierfrancesco Tassone

1 reference

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30 April 2020

Pierosandro Tagliaferri

object named as

Pierosandro Tagliaferri

1 reference

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30 April 2020

Maria Cucè

1 reference

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30 April 2020

Maria Eugenia Gallo Cantafio

1 reference

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30 April 2020

Maria Anna Siciliano

1 reference

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30 April 2020

Caterina Riillo

1 reference

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30 April 2020

Daniele Caracciolo

1 reference

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30 April 2020

Francesca Scionti

1 reference

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30 April 2020

Nicoletta Staropoli

1 reference

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30 April 2020

Valeria Zuccalà

1 reference

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30 April 2020

Lorenza Maltese

1 reference

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30 April 2020

Katia Grillone

1 reference

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30 April 2020

Vito Barbieri

1 reference

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30 April 2020

Mariamena Arbitrio

1 reference

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30 April 2020

Maria Teresa Di Martino

1 reference

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30 April 2020

Nicola Amodio

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30898137%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

language of work or name

English

0 references

publication date

21 March 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30898137%20AND%20SRC:MED&resulttype=core&format=json

Journal of Hematology & Oncology

30 April 2020

published in

1 reference

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30 April 2020

volume

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30 April 2020

issue

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30 April 2020

page(s)

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Creative Commons Attribution 4.0 International

30 April 2020

start time

21 March 2019

1 reference

April 2022 Public Data File from Crossref

copyrighted

0 references

describes a project that uses

Cytoscape

object named as

Cytoscape

2 references

9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

inferred from PubMed Central ID database lookup

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

cites work

Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma

1 reference

12 December 2020

Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation

1 reference

12 December 2020

Chk2 activates E2F-1 in response to DNA damage

1 reference

12 December 2020

HLA class I, NKG2D, and natural cytotoxicity receptors regulate multiple myeloma cell recognition by natural killer cells

1 reference

12 December 2020

The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor

1 reference

12 December 2020

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

1 reference

12 December 2020

Molecular characterization of human multiple myeloma cell lines by integrative genomics: insights into the biology of the disease.

1 reference

12 December 2020

Gamma-H2AX - a novel biomarker for DNA double-strand breaks.

1 reference

12 December 2020

MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis

1 reference

12 December 2020

ATM-ATR-dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is associated with a senescent phenotype

1 reference

12 December 2020

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

1 reference

12 December 2020

Macrophages are an abundant component of myeloma microenvironment and protect myeloma cells from chemotherapy drug-induced apoptosis

1 reference

12 December 2020

A review of trabectedin (ET-743): a unique mechanism of action.

1 reference

12 December 2020

Predictive impact of DNA repair functionality on clinical outcome of advanced sarcoma patients treated with trabectedin: a retrospective multicentric study.

1 reference

12 December 2020

miR-17-92 cluster microRNAs confers tumorigenicity in multiple myeloma

1 reference

12 December 2020

XPF-dependent DNA breaks and RNA polymerase II arrest induced by antitumor DNA interstrand crosslinking-mimetic alkaloids.

1 reference

12 December 2020

Transcriptional and nontranscriptional functions of E2F1 in response to DNA damage

1 reference

12 December 2020

The role of natural killer cells in immunity against multiple myeloma

1 reference

12 December 2020

A systems biology approach to characterize the regulatory networks leading to trabectedin resistance in an in vitro model of myxoid liposarcoma

1 reference

12 December 2020

The microRNA-17-92 family of microRNA clusters in development and disease

1 reference

12 December 2020

Histone H2AX phosphorylation: a marker for DNA damage

1 reference

12 December 2020

MiR-15a, miR-16-1 and miR-17-92 cluster expression are linked to poor prognosis in multiple myeloma

1 reference

12 December 2020

CluePedia Cytoscape plugin: pathway insights using integrated experimental and in silico data

1 reference

12 December 2020

Analysis of DNA repair-related genes in breast cancer reveals CUL4A ubiquitin ligase as a novel biomarker of trabectedin response.

1 reference

12 December 2020

Role of Macrophage Targeting in the Antitumor Activity of Trabectedin

1 reference

12 December 2020

Immunologic microenvironment and personalized treatment in multiple myeloma.

1 reference

12 December 2020

A diverse induction of apoptosis by trabectedin in MCF-7 (HER2-/ER+) and MDA-MB-453 (HER2+/ER-) breast cancer cells.

1 reference

12 December 2020

DNA repair pathways in human multiple myeloma: role in oncogenesis and potential targets for treatment

1 reference

12 December 2020

Natural killer T cell defects in multiple myeloma and the impact of lenalidomide therapy

1 reference

12 December 2020

Trabectedin mechanism of action: what's new?

1 reference

12 December 2020

The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins

1 reference

12 December 2020

The DNA Damage Response: A Common Pathway in the Regulation of NKG2D and DNAM-1 Ligand Expression in Normal, Infected, and Cancer Cells.

1 reference

12 December 2020

Automated quantification reveals hyperglycemia inhibits endothelial angiogenic function

1 reference

12 December 2020

CD28-mediated pro-survival signaling induces chemotherapeutic resistance in multiple myeloma

1 reference

12 December 2020

A DNA repair pathway score predicts survival in human multiple myeloma: the potential for therapeutic strategy

1 reference

12 December 2020

Reactive oxygen species- and DNA damage response-dependent NK cell activating ligand upregulation occurs at transcriptional levels and requires the transcriptional factor E2F1.

1 reference

12 December 2020

Histone deacetylase inhibitor SAHA epigenetically regulates miR-17-92 cluster and MCM7 to upregulate MICA expression in hepatoma.

1 reference

12 December 2020

The cellular immune system in myelomagenesis: NK cells and T cells in the development of myeloma [corrected] and their uses in immunotherapies

1 reference

12 December 2020

Transcription factor IKZF1 is degraded during the apoptosis of multiple myeloma cells induced by kinase inhibition

1 reference

12 December 2020

Revised International Staging System for Multiple Myeloma: A Report From International Myeloma Working Group

1 reference

12 December 2020

Effects of p21-activated kinase 1 inhibition on 11q13-amplified ovarian cancer cells

1 reference

12 December 2020

The IMiDs targets IKZF-1/3 and IRF4 as novel negative regulators of NK cell-activating ligands expression in multiple myeloma

1 reference

12 December 2020

A 13 mer LNA-i-miR-221 Inhibitor Restores Drug Sensitivity in Melphalan-Refractory Multiple Myeloma Cells.

1 reference

12 December 2020

Therapeutic Targeting of miR-29b/HDAC4 Epigenetic Loop in Multiple Myeloma.

1 reference

12 December 2020

A landscape of pharmacogenomic interactions in cancer.

1 reference

12 December 2020

DNA repair of myeloma plasma cells correlates with clinical outcome: the effect of the nonhomologous end-joining inhibitor SCR7.

1 reference

12 December 2020

microRNAs with AAGUGC seed motif constitute an integral part of an oncogenic signaling network

1 reference

12 December 2020

Inhibition of bromodomain and extra-terminal (BET) proteins increases NKG2D ligand MICA expression and sensitivity to NK cell-mediated cytotoxicity in multiple myeloma cells: role of cMYC-IRF4-miR-125b interplay

1 reference

12 December 2020

A gene expression inflammatory signature specifically predicts multiple myeloma evolution and patients survival.

1 reference

12 December 2020

Antitumour activity of trabectedin in myelodysplastic/myeloproliferative neoplasms.

1 reference

12 December 2020

Immunomodulatory activity of microRNAs: potential implications for multiple myeloma treatment

1 reference

12 December 2020

Silencing NKG2D ligand-targeting miRNAs enhances natural killer cell-mediated cytotoxicity in breast cancer

1 reference

12 December 2020

ILF2 Is a Regulator of RNA Splicing and DNA Damage Response in 1q21-Amplified Multiple Myeloma

1 reference

12 December 2020

An E2F1/MiR-17-92 Negative Feedback Loop mediates proliferation of Mouse Palatal Mesenchymal Cells

1 reference

12 December 2020

Natural Killer Cell Response to Chemotherapy-Stressed Cancer Cells: Role in Tumor Immunosurveillance.

1 reference

12 December 2020

Resveratrol promotes MICA/B expression and natural killer cell lysis of breast cancer cells by suppressing c-Myc/miR-17 pathway

1 reference

12 December 2020

Regulation of E2F1 Transcription Factor by Ubiquitin Conjugation.

1 reference

12 December 2020

MiR-29b antagonizes the pro-inflammatory tumor-promoting activity of multiple myeloma-educated dendritic cells

1 reference

12 December 2020

Network meta-analysis of randomized trials in multiple myeloma: efficacy and safety in relapsed/refractory patients

1 reference

12 December 2020

Therapeutic vulnerability of multiple myeloma to MIR17PTi, a first-in-class inhibitor of pri-miR-17-92

1 reference

12 December 2020

miR-22 suppresses DNA ligase III addiction in multiple myeloma

1 reference

12 December 2020

The potential role of miRNAs in multiple myeloma therapy

1 reference

12 December 2020

10.1186/S13045-019-0714-9

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30898137%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

30 April 2020

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/s13045-019-0714-9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30898137%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

PubMed publication ID

30898137

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30898137%20AND%20SRC:MED&resulttype=core&format=json