(Q58417540)

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Variants of transcription factor 7-like 2 (TCF7L2) gene predict conversion to type 2 diabetes in the Finnish Diabetes Prevention Study and are associated with impaired glucose regulation and impaired insulin secretion

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Variants of transcription factor 7-like 2 (TCF7L2) gene predict conversion to type 2 diabetes in the Finnish Diabetes Prevention Study and are associated with impaired glucose regulation and impaired insulin secretion (English)

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type 2 diabetes

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Jaana Lindström

object named as

J. Lindström

5

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8

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M. Laakso

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Jaakko Tuomilehto

6

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J. Tuomilehto

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Johanna Kuusisto

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J. Kuusisto

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author name string

J. Wang

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M. Vänttinen

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T. Kuulasmaa

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M. Uusitupa

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publication date

17 April 2007

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50

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6

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1192-1200

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A simple method for quantitation of insulin sensitivity and insulin release from an intravenous glucose tolerance test

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https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

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TCF7L2 variation predicts hyperglycemia incidence in a French general population: the data from an epidemiological study on the Insulin Resistance Syndrome (DESIR) study

1 reference

https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

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Common variants in the TCF7L2 gene and predisposition to type 2 diabetes in UK European Whites, Indian Asians and Afro-Caribbean men and women

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https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

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Making the right associations

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https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

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Polymorphisms in the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in the Amish: replication and evidence for a role in both insulin secretion and insulin resistance.

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https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

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Diabetes mellitus. Report of a WHO Study Group

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https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

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TCF7L2 and type 2 diabetes--we WNT to know

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https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

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Role of insulin secretion and sensitivity in the evolution of type 2 diabetes in the diabetes prevention program: effects of lifestyle intervention and metformin

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https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

based on heuristic

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Association of Transcription Factor 7-Like 2 (TCF7L2) Variants With Type 2 Diabetes in a Finnish Sample

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https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

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Transcription Factor TCF7L2 Genetic Study in the French Population: Expression in Human -Cells and Adipose Tissue and Strong Association With Type 2 Diabetes

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https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

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Potential use of bioelectrical impedance of the 'whole body' and of body segments for the assessment of body composition: comparison with densitometry and anthropometry.

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https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

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Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphism in the transcription factor 7-like 2 (TCF7L2) gene is associated with reduced insulin secretion in nondiabetic women

1 reference

https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

based on heuristic

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TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program

1 reference

https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of variants of transcription factor 7-like 2 (TCF7L2) with susceptibility to type 2 diabetes in the Dutch Breda cohort

1 reference

https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

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Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function

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https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

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Association Analysis of 6,736 U.K. Subjects Provides Replication and ConfirmsTCF7L2as a Type 2 Diabetes Susceptibility Gene With a Substantial Effect on Individual Risk

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https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

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TCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase-3beta

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https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

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Long-term improvement in insulin sensitivity by changing lifestyles of people with impaired glucose tolerance: 4-year results from the Finnish Diabetes Prevention Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

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The glucagon-like peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

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Multiple abnormalities in glucose and energy metabolism and coordinated changes in levels of adiponectin, cytokines, and adhesion molecules in subjects with metabolic syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

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Understanding oral glucose tolerance: comparison of glucose or insulin measurements during the oral glucose tolerance test with specific measurements of insulin resistance and insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

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Prevention of Type II diabetes in subjects with impaired glucose tolerance: the Diabetes Prevention Study (DPS) in Finland. Study design and 1-year interim report on the feasibility of the lifestyle intervention programme

1 reference

https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

based on heuristic

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Defects in insulin secretion and insulin action in non-insulin-dependent diabetes mellitus are inherited. Metabolic studies on offspring of diabetic probands

1 reference

https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

based on heuristic

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Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance

1 reference

https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

based on heuristic

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Glucose clamp technique: a method for quantifying insulin secretion and resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

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Inhibition of adipogenesis by Wnt signaling

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https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

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A role for glucagon-like peptide-1 in the central regulation of feeding

1 reference

https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

based on heuristic

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Variant of Transcription Factor 7-Like 2 (TCF7L2) Gene and the Risk of Type 2 Diabetes in Large Cohorts of U.S. Women and Men

1 reference

https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Common variants in the TCF7L2 gene are strongly associated with type 2 diabetes mellitus in the Indian population.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

based on heuristic

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Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/17437080

12 December 2020

based on heuristic

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10.1007/S00125-007-0656-6

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