(Q58035710)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17213193%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

title

Cooperativity in cytochrome P450 3A4: linkages in substrate binding, spin state, uncoupling, and product formation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17213193%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17213193%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Bradley J Baas

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17213193%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Yelena V Grinkova

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17213193%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Stephen G Sligar

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17213193%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

language of work or name

English

0 references

publication date

9 January 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17213193%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

24 December 2019

published in

1 reference

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24 December 2019

volume

282

1 reference

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24 December 2019

issue

1 reference

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24 December 2019

page(s)

7066-7076

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17213193%20AND%20SRC:MED&resulttype=core&format=json

Cytochrome P-450 3A4: regulation and role in drug metabolism

24 December 2019

cites work

1 reference

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Interactions of mammalian cytochrome P450, NADPH-cytochrome P450 reductase, and cytochrome b(5) enzymes

21 January 2018

1 reference

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Analysis of Four Residues within Substrate Recognition Site 4 of Human Cytochrome P450 3A4: Role in Steroid Hydroxylase Activity and α-Naphthoflavone Stimulation

21 January 2018

1 reference

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Phenylalanine and tryptophan scanning mutagenesis of CYP3A4 substrate recognition site residues and effect on substrate oxidation and cooperativity

21 January 2018

1 reference

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The thermodynamic landscape of testosterone binding to cytochrome P450 3A4: ligand binding and spin state equilibria

21 January 2018

1 reference

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Kinetics and thermodynamics of ligand binding by cytochrome P450 3A4.

21 January 2018

1 reference

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Role of phospholipids in reconstituted cytochrome P 450 3A form and mechanism of their activation of catalytic activity

21 January 2018

1 reference

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Roles of divalent metal ions in oxidations catalyzed by recombinant cytochrome P450 3A4 and replacement of NADPH--cytochrome P450 reductase with other flavoproteins, ferredoxin, and oxygen surrogates.

21 January 2018

1 reference

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The structure of human microsomal cytochrome P450 3A4 determined by X-ray crystallography to 2.05-A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609589200

Structural basis for ligand promiscuity in cytochrome P450 3A4.

21 January 2018

1 reference

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Resolution of multiple substrate binding sites in cytochrome P450 3A4: the stoichiometry of the enzyme-substrate complexes probed by FRET and Job's titration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609589200

Homotropic cooperativity of monomeric cytochrome P450 3A4 in a nanoscale native bilayer environment

21 January 2018

1 reference

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Self‐assembly of single integral membrane proteins into soluble nanoscale phospholipid bilayers

21 January 2018

1 reference

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Co-incorporation of heterologously expressed Arabidopsis cytochrome P450 and P450 reductase into soluble nanoscale lipid bilayers

21 January 2018

1 reference

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Functional reconstitution of Beta2-adrenergic receptors utilizing self-assembling Nanodisc technology

21 January 2018

1 reference

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Nanodiscs separate chemoreceptor oligomeric states and reveal their signaling properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609589200

Directed self-assembly of monodisperse phospholipid bilayer Nanodiscs with controlled size

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609589200

Thermotropic phase transition in soluble nanoscale lipid bilayers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609589200

Self-Assembly of Discoidal Phospholipid Bilayer Nanoparticles with Membrane Scaffold Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609589200

Expression of modified human cytochrome P450 3A4 in Escherichia coli and purification and reconstitution of the enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609589200

Biphasic response for hepatic microsomal enzyme induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin in C57BL/6J and DBA/2J mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609589200

A simple procedure for removal of Triton X-100 from protein samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609589200

Testosterone 1 beta-hydroxylation by human cytochrome P450 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609589200

Global analysis of biochemical and biophysical data

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609589200

Kinetics of dithionite-dependent reduction of cytochrome P450 3A4: heterogeneity of the enzyme caused by its oligomerization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609589200

Oxidation of nonionic detergents by cytochrome P450 enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609589200

Coupling of spin, substrate, and redox equilibriums in cytochrome P450

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609589200

Kinetics of Ferric Cytochrome P450 Reduction by NADPH−Cytochrome P450 Reductase: Rapid Reduction in the Absence of Substrate and Variations among Cytochrome P450 Systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609589200

Membrane properties induced by anionic phospholipids and phosphatidylethanolamine are critical for the membrane binding and catalytic activity of human cytochrome P450 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609589200

Cooperativity in oxidations catalyzed by cytochrome P450 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609589200

Analysis of human cytochrome P450 3A4 cooperativity: construction and characterization of a site-directed mutant that displays hyperbolic steroid hydroxylation kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609589200

Conformational heterogeneity of cytochrome P450 3A4 revealed by high pressure spectroscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609589200

The Ferrous-Dioxygen Intermediate in Human Cytochrome P450 3A4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609589200

Single-molecule height measurements on microsomal cytochrome P450 in nanometer-scale phospholipid bilayer disks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609589200

Reconstitution of the enzymatic activities of cytochrome P450s using recombinant flavocytochromes containing rat cytochrome b(5) fused to NADPH--cytochrome P450 reductase with various membrane-binding segments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609589200

Modelling atypical CYP3A4 kinetics: principles and pragmatism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609589200

Structures of cytochrome P450 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609589200

The catalytic pathway of cytochrome p450cam at atomic resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609589200

Structure and chemistry of cytochrome P450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609589200

Roles of Cytochrome b5in the Oxidation of Testosterone and Nifedipine by Recombinant Cytochrome P450 3A4 and by Human Liver Microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609589200

21 January 2018

Identifiers

DOI

10.1074/JBC.M609589200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17213193%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17213193%20AND%20SRC:MED&resulttype=core&format=json