(Q57651552)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22268122%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

Deregulated Stat3 signaling dissociates pulmonary inflammation from emphysema in gp130 mutant mice (English)

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20 January 2020

0 references

1 reference

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20 January 2020

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20 January 2020

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20 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22268122%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Louise McLeod

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22268122%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Alistair Miller

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20 January 2020

Jessica Jones

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20 January 2020

Ross Vlahos

1 reference

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20 January 2020

Anthony Longano

1 reference

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20 January 2020

Philip G Bardin

1 reference

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20 January 2020

Gary P Anderson

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20 January 2020

publication date

20 January 2012

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22268122%20AND%20SRC:MED&resulttype=core&format=json

American Journal of Physiology - Lung Cellular and Molecular Physiology

20 January 2020

published in

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20 January 2020

volume

302

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20 January 2020

issue

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20 January 2020

page(s)

L627-39

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Alveolar wall apoptosis causes lung destruction and emphysematous changes

20 January 2020

cites work

1 reference

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Blockade of interleukin 6 trans signaling suppresses T-cell resistanceagainst apoptosis in chronic intestinal inflammation: Evidence in Crohn diseaseand experimental colitis in vivo

21 January 2018

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Chronic obstructive pulmonary disease: molecular and cellularmechanisms

21 January 2018

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TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling.

21 January 2018

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Serum amyloid a is a biomarker of acute exacerbations of chronic obstructive pulmonary disease

21 January 2018

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Hyperresponsiveness to inhaled but not intravenous methacholine during acute respiratory syncytial virus infection in mice

21 January 2018

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Requirement of matrix metalloproteinase-9 for the transformation of human mammary epithelial cells by Stat3-C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00285.2011

Role of apoptosis in the pathogenesis of COPD and pulmonary emphysema

21 January 2018

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Stat3 activation in acute lung injury

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00285.2011

STAT3 and suppressor of cytokine signaling 3: potential targets in lung inflammatory responses

21 January 2018

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Increased number of B-cells in bronchial biopsies in COPD.

21 January 2018

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IL-6 trans-signaling modulates TLR4-dependent inflammatory responses via STAT3.

21 January 2018

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Associations of IL6 polymorphisms with lung function decline and COPD.

21 January 2018

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Principles of interleukin (IL)-6-type cytokine signalling and its regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00285.2011

Increased airway epithelial and T-cell apoptosis in COPD remains despite smoking cessation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00285.2011

Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00285.2011

IL-6 transsignaling: the in vivo consequences

21 January 2018

1 reference

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Understanding the inflammatory cytokine response in pneumonia and sepsis: results of the Genetic and Inflammatory Markers of Sepsis (GenIMS) Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00285.2011

GP130-STAT3 regulates epithelial cell migration and is required for repair of the bronchiolar epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00285.2011

Airway hyperresponsiveness and airway obstruction in transgenic mice. Morphologic correlates in mice overexpressing interleukin (IL)-11 and IL-6 in the lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00285.2011

Although IL-6 Trans-Signaling Is Sufficient To Drive Local Immune Responses, Classical IL-6 Signaling Is Obligate for the Induction of T Cell-Mediated Autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00285.2011

Decoy oligodeoxynucleotide against STAT transcription factors decreases allergic inflammation in a rat asthma model

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00285.2011

Pulmonary and systemic oxidant/antioxidant imbalance in chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00285.2011

IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation.

21 January 2018

1 reference

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The Epithelial Cell in Lung Health and Emphysema Pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00285.2011

Therapeutic targeting of IL-6 trans signaling counteracts STAT3 control of experimental inflammatory arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00285.2011

A novel antiapoptotic role for alpha1-antitrypsin in the prevention of pulmonary emphysema

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00285.2011

Matrix metalloproteinase 12 overexpression in lung epithelial cells plays a key role in emphysema to lung bronchioalveolar adenocarcinoma transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00285.2011

Stat3 downstream genes serve as biomarkers in human lung carcinomas and chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00285.2011

Interleukin-6 promotes pulmonary emphysema associated with apoptosis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00285.2011

Increased cytokine response of rhinovirus-infected airway epithelial cells in chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00285.2011

JAK1 activates STAT3 activity in non-small-cell lung cancer cells and IL-6 neutralizing antibodies can suppress JAK1-STAT3 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00285.2011

Proteinase-activated receptor-1 mediates elastase-induced apoptosis of human lung epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00285.2011

Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00285.2011

Differential protease, innate immunity, and NF-kappaB induction profiles during lung inflammation induced by subchronic cigarette smoke exposure in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00285.2011

Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFkappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00285.2011

Synergy between signal transducer and activator of transcription 3 and retinoic acid receptor-alpha in regulation of the surfactant protein B gene in the lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00285.2011

Increased levels of cell death and proliferation in alveolar wall cells in patients with pulmonary emphysema

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00285.2011

Role of cathepsin S-dependent epithelial cell apoptosis in IFN-gamma-induced alveolar remodeling and pulmonary emphysema

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00285.2011

10.1152/AJPLUNG.00285.2011

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22268122%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

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