(Q57458211)

English

Long noncoding RNA AFAP1-AS1 acts as a competing endogenous RNA of miR-423-5p to facilitate nasopharyngeal carcinoma metastasis through regulating the Rho/Rac pathway

scientific article published on 16 October 2018

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28 April 2020

Long noncoding RNA AFAP1-AS1 acts as a competing endogenous RNA of miR-423-5p to facilitate nasopharyngeal carcinoma metastasis through regulating the Rho/Rac pathway (English)

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28 April 2020

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Yu Lian

1

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28 April 2020

Fang Xiong

2

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28 April 2020

Liting Yang

3

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28 April 2020

Hao Bo

4

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28 April 2020

Zhaojian Gong

5

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28 April 2020

Yumin Wang

6

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28 April 2020

Fang Wei

7

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28 April 2020

Yanyan Tang

8

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28 April 2020

Xiayu Li

9

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28 April 2020

Qianjin Liao

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28 April 2020

Hui Wang

11

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28 April 2020

Ming Zhou

12

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28 April 2020

Bo Xiang

13

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28 April 2020

Xu Wu

14

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28 April 2020

Yong Li

15

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28 April 2020

Xiaoling Li

16

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28 April 2020

Xiang Chen

17

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28 April 2020

Guiyuan Li

18

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28 April 2020

Can Guo

19

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28 April 2020

Zhaoyang Zeng

20

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28 April 2020

Wei Xiong

21

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28 April 2020

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16 October 2018

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28 April 2020

Journal of Experimental & Clinical Cancer Research

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28 April 2020

37

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28 April 2020

1

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28 April 2020

253

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28 April 2020

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Creative Commons Attribution 4.0 International

16 October 2018

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April 2022 Public Data File from Crossref

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0 references

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AP-1 as a regulator of cell life and death

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Actin binding of human LIM and SH3 protein is regulated by cGMP- and cAMP-dependent protein kinase phosphorylation on serine 146.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A susceptibility locus at chromosome 3p21 linked to familial nasopharyngeal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Silencing of LASP-1 influences zyxin localization, inhibits proliferation and reduces migration in breast cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Family-based association analysis validates chromosome 3p21 as a putative nasopharyngeal carcinoma susceptibility locus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-wide expression profiling reveals EBV-associated inhibition of MHC class I expression in nasopharyngeal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language?

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nasopharyngeal carcinoma: Advances in genomics and molecular genetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An in silico analysis of dynamic changes in microRNA expression profiles in stepwise development of nasopharyngeal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LIM and SH3 protein 1, a promoter of cell proliferation and migration, is a novel independent prognostic indicator in hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypomethylation of noncoding DNA regions and overexpression of the long noncoding RNA, AFAP1-AS1, in Barrett's esophagus and esophageal adenocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of LINC00312, a long intergenic non-coding RNA, is negatively correlated with tumor size but positively correlated with lymph node metastasis in nasopharyngeal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LPLUNC1 inhibits nasopharyngeal carcinoma cell growth via down-regulation of the MAP kinase and cyclin D1/E2F pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LPLUNC1 suppresses IL-6-induced nasopharyngeal carcinoma cell proliferation via inhibiting the Stat3 activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rab11b mediates melanin transfer between donor melanocytes and acceptor keratinocytes via coupled exo/endocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The multilayered complexity of ceRNA crosstalk and competition

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

miRNA423-5p regulates cell proliferation and invasion by targeting trefoil factor 1 in gastric cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation network and expression profiles of Epstein-Barr virus-encoded microRNAs and their potential target host genes in nasopharyngeal carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pseudogene PTENP1 functions as a competing endogenous RNA to suppress clear-cell renal cell carcinoma progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FOSL2 positively regulates TGF-β1 signalling in non-small cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LOC401317, a p53-regulated long non-coding RNA, inhibits cell proliferation and induces apoptosis in the nasopharyngeal carcinoma cell line HNE2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PTEN ceRNA networks in human cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a microRNA signature associated with risk of distant metastasis in nasopharyngeal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MicroRNA-423-5p Promotes Autophagy in Cancer Cells and Is Increased in Serum From Hepatocarcinoma Patients Treated With Sorafenib.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epstein-Barr virus-encoded microRNA BART1 induces tumour metastasis by regulating PTEN-dependent pathways in nasopharyngeal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AFAP1-AS1, a long noncoding RNA upregulated in lung cancer and promotes invasion and metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epstein-Barr virus-encoded small RNA 1 (EBER-1) could predict good prognosis in nasopharyngeal carcinoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrating ChIP-sequencing and digital gene expression profiling to identify BRD7 downstream genes and construct their regulating network

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An integrative transcriptomic analysis reveals p53 regulated miRNA, mRNA, and lncRNA networks in nasopharyngeal carcinoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The up-regulation of long non-coding RNA AFAP1-AS1 is associated with the poor prognosis of NSCLC patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EBV-miR-BART10-3p facilitates epithelial-mesenchymal transition and promotes metastasis of nasopharyngeal carcinoma by targeting BTRC

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Critical role for the long non-coding RNA AFAP1-AS1 in the proliferation and metastasis of hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HYOU1, Regulated by LPLUNC1, Is Up-Regulated in Nasopharyngeal Carcinoma and Associated with Poor Prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

miR-3188 regulates nasopharyngeal carcinoma proliferation and chemosensitivity through a FOXO1-modulated positive feedback loop with mTOR-p-PI3K/AKT-c-JUN.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epstein-Barr virus encoded miR-BART11 promotes inflammation-induced carcinogenesis by targeting FOXP1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Long Noncoding RNA MALAT-1 is A Novel Biomarker in Various Cancers: A Meta-analysis Based on the GEO Database and Literature

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pseudogene PTENP1 Functions as a Competing Endogenous RNA (ceRNA) to Regulate PTEN Expression by Sponging miR-499-5p

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epstein-Barr virus-encoded miR-BART6-3p inhibits cancer cell metastasis and invasion by targeting long non-coding RNA LOC553103.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of long non-coding RNA expression profiles in pancreatic ductal adenocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression long non-coding RNA LINC00673 is associated with poor prognosis and promotes invasion and metastasis in tongue squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LIM and SH3 protein 1 promotes tumor proliferation and metastasis in lung carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High Expression of LINC01420 indicates an unfavorable prognosis and modulates cell migration and invasion in nasopharyngeal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circular RNAs in human cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Linking long non-coding RNAs and SWI/SNF complexes to chromatin remodeling in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulated long non-coding RNA LINC00152 expression is associated with progression and poor prognosis of tongue squamous cell carcinoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Co-expression of AFAP1-AS1 and PD-1 predicts poor prognosis in nasopharyngeal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of tumor microenvironment in tumorigenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-Wide Analysis of 18 Epstein-Barr Viruses Isolated from Primary Nasopharyngeal Carcinoma Biopsy Specimens

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of long non-coding RNAs in glucose metabolism in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vimentin is a crucial target for anti-metastasis therapy of nasopharyngeal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

circGFRA1 and GFRA1 act as ceRNAs in triple negative breast cancer by regulating miR-34a

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BPIFB1 (LPLUNC1) inhibits migration and invasion of nasopharyngeal carcinoma by interacting with VTN and VIM.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trend analysis of cancer incidence and mortality in China

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long non-coding RNA AFAP1-AS1 is a novel biomarker in various cancers: a systematic review and meta-analysis based on the literature and GEO datasets

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rediscovery of NF-κB signaling in nasopharyngeal carcinoma: How genetic defects of NF-κB pathway interplay with EBV in driving oncogenesis?

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LncRNAs regulate cancer metastasis via binding to functional proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long non-coding RNA PVT1 predicts poor prognosis and induces radioresistance by regulating DNA repair and cell apoptosis in nasopharyngeal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Function of the c-Met receptor tyrosine kinase in carcinogenesis and associated therapeutic opportunities

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of exosomal non-coding RNAs in cancer metastasis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BPIFB1 (LPLUNC1) inhibits radioresistance in nasopharyngeal carcinoma by inhibiting VTN expression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LncRNAs regulate the cytoskeleton and related Rho/ROCK signaling in cancer metastasis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circular RNAs (circRNAs) in cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circular RNAs function as ceRNAs to regulate and control human cancer progression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of metabolism in cancer cell radioresistance and radiosensitization methods.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual-functionality of RASSF1A overexpression in A375 cells is mediated by activation of IL-6/STAT3 regulatory loop

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of genomic alterations in nasopharyngeal carcinoma and nasopharyngeal carcinoma-derived Epstein-Barr virus by whole genome sequencing

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The emerging role of Epstein-Barr virus encoded microRNAs in nasopharyngeal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibin B suppresses anoikis resistance and migration through the transforming growth factor-β signaling pathway in nasopharyngeal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30326930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/S13046-018-0918-9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30326930%20AND%20SRC:MED&resulttype=core&format=json

28 April 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30326930%20AND%20SRC:MED&resulttype=core&format=json

28 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30326930%20AND%20SRC:MED&resulttype=core&format=json

28 April 2020

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