(Q57186574)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30292489%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

title

The impact of lipids, lipid oxidation, and inflammation on AMD, and the potential role of miRNAs on lipid metabolism in the RPE (English)

1 reference

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26 April 2020

0 references

1 reference

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26 April 2020

Sujung Jun

1 reference

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26 April 2020

Sayantan Datta

1 reference

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26 April 2020

Roma Pegany

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26 April 2020

Marisol Cano

1 reference

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26 April 2020

James T Handa

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26 April 2020

language of work or name

English

0 references

publication date

5 October 2018

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Experimental Eye Research

26 April 2020

published in

1 reference

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26 April 2020

volume

181

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26 April 2020

page(s)

346-355

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Histologic analysis of photochemical lesions produced in rhesus retina by short-wave-length light

26 April 2020

cites work

1 reference

12 December 2020

Lipoprotein apoprotein metabolism

1 reference

12 December 2020

Plasma lipoproteins, lipid transport, and atherosclerosis: recent developments

1 reference

12 December 2020

Visual function and the subsequent development of exudative age-related macular degeneration

1 reference

12 December 2020

Antisera and monoclonal antibodies specific for epitopes generated during oxidative modification of low density lipoprotein.

1 reference

12 December 2020

Functional loss in age-related Bruch's membrane change with choroidal perfusion defect

1 reference

12 December 2020

Low density lipoprotein undergoes oxidative modification in vivo

1 reference

12 December 2020

A genetic pathway for the specification of the vulval cell lineages of Caenorhabditis elegans.

1 reference

12 December 2020

Analysis of newly synthesized Bruch's membrane proteoglycans

1 reference

12 December 2020

Detection of specific extracellular matrix molecules in drusen, Bruch's membrane, and ciliary body

1 reference

12 December 2020

Heterochronic mutants of the nematode Caenorhabditis elegans.

1 reference

12 December 2020

ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis. Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehyde-lysine in serum.

1 reference

12 December 2020

Sibling correlations and segregation analysis of age-related maculopathy: the Beaver Dam Eye Study.

1 reference

12 December 2020

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

1 reference

12 December 2020

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

1 reference

12 December 2020

ADD1: a novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation

1 reference

12 December 2020

Epidemiology of age-related maculopathy.

1 reference

12 December 2020

Identification of glycosaminoglycans in age-related macular deposits

1 reference

12 December 2020

Two tandem binding sites for sterol regulatory element binding proteins are required for sterol regulation of fatty-acid synthase promoter

1 reference

12 December 2020

Macular function impairment in eyes with early age-related macular degeneration

1 reference

12 December 2020

Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells

1 reference

12 December 2020

Cholesterol feeding reduces nuclear forms of sterol regulatory element binding proteins in hamster liver

1 reference

12 December 2020

Genes for apolipoprotein B and microsomal triglyceride transfer protein are expressed in the heart: evidence that the heart has the capacity to synthesize and secrete lipoproteins

1 reference

12 December 2020

Increase in the advanced glycation end product pentosidine in Bruch's membrane with age.

1 reference

12 December 2020

Characterization of peroxidized lipids in Bruch's membrane

1 reference

12 December 2020

Nonoxidative modifications of lipoproteins in atherogenesis

1 reference

12 December 2020

Oxidative damage and age-related macular degeneration

1 reference

12 December 2020

Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease

1 reference

12 December 2020

Photoreceptor phagocytosis selectively activates PPARgamma expression in retinal pigment epithelial cells

1 reference

12 December 2020

Ultrastructural changes in Bruch's membrane of apolipoprotein E-deficient mice

1 reference

12 December 2020

The relative toxicity of compounds in mainstream cigarette smoke condensate

1 reference

12 December 2020

Accumulation of cholesterol with age in human Bruch's membrane.

1 reference

12 December 2020

A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8

1 reference

12 December 2020

Overexpression of apolipoprotein B in the heart impedes cardiac triglyceride accumulation and development of cardiac dysfunction in diabetic mice

1 reference

12 December 2020

ANGPTL3 decreases very low density lipoprotein triglyceride clearance by inhibition of lipoprotein lipase

1 reference

12 December 2020

A microRNA in a multiple-turnover RNAi enzyme complex

1 reference

12 December 2020

Drusen proteome analysis: an approach to the etiology of age-related macular degeneration.

1 reference

12 December 2020

Apolipoprotein B in cholesterol-containing drusen and basal deposits of human eyes with age-related maculopathy

1 reference

12 December 2020

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment

1 reference

12 December 2020

Apolipoprotein B production reduces lipotoxic cardiomyopathy: studies in heart-specific lipoprotein lipase transgenic mouse

1 reference

12 December 2020

Current concepts in the pathogenesis of age-related macular degeneration

1 reference

12 December 2020

Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice

1 reference

12 December 2020

Global data on visual impairment in the year 2002

1 reference

12 December 2020

Retina expresses microsomal triglyceride transfer protein: implications for age-related maculopathy.

1 reference

12 December 2020

Complement factor H variant increases the risk of age-related macular degeneration

1 reference

12 December 2020

Complement factor H polymorphism and age-related macular degeneration

1 reference

12 December 2020

Complement factor H polymorphism in age-related macular degeneration

1 reference

12 December 2020

Risk factors for the incidence of Advanced Age-Related Macular Degeneration in the Age-Related Eye Disease Study (AREDS) AREDS report no. 19

1 reference

12 December 2020

A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration

1 reference

12 December 2020

Candidate gene analysis suggests a role for fatty acid biosynthesis and regulation of the complement system in the etiology of age-related maculopathy

1 reference

12 December 2020

Basal deposits and drusen in eyes with age-related maculopathy: evidence for solid lipid particles

1 reference

12 December 2020

Esterified and unesterified cholesterol in drusen and basal deposits of eyes with age-related maculopathy

1 reference

12 December 2020

Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration

1 reference

12 December 2020

The potential role of amyloid beta in the pathogenesis of age-related macular degeneration

1 reference

12 December 2020

miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting

1 reference

12 December 2020

High density lipoprotein mediated lipid efflux from retinal pigment epithelial cells in culture

1 reference

12 December 2020

Plasma apolipoproteins and risk for age related maculopathy

1 reference

12 December 2020

Apolipoprotein localization in isolated drusen and retinal apolipoprotein gene expression

1 reference

12 December 2020

Angiopoietin-like protein3 regulates plasma HDL cholesterol through suppression of endothelial lipase

1 reference

12 December 2020

Intraretinal lipid transport is dependent on high density lipoprotein-like particles and class B scavenger receptors

1 reference

12 December 2020

Regulation of Triglyceride Metabolism. II. Function of mitochondrial GPAT1 in the regulation of triacylglycerol biosynthesis and insulin action

1 reference

12 December 2020

New molecular histopathologic insights into the pathogenesis of age-related macular degeneration

1 reference

12 December 2020

Oxidized phospholipids in the macula increase with age and in eyes with age-related macular degeneration

1 reference

12 December 2020

The lipofuscin fluorophore A2E perturbs cholesterol metabolism in retinal pigment epithelial cells

1 reference

12 December 2020

Oxidative damage in age-related macular degeneration

1 reference

12 December 2020

Subendothelial lipoprotein retention as the initiating process in atherosclerosis: update and therapeutic implications

1 reference

12 December 2020

Regulation of progenitor cell proliferation and granulocyte function by microRNA-223

1 reference

12 December 2020

LNA-mediated microRNA silencing in non-human primates

1 reference

12 December 2020

Oxidation-specific epitopes are important targets of innate immunity

1 reference

12 December 2020

Sub-retinal drusenoid deposits in human retina: organization and composition

1 reference

12 December 2020

7-Ketocholesterol is present in lipid deposits in the primate retina: potential implication in the induction of VEGF and CNV formation

1 reference

12 December 2020

Most mammalian mRNAs are conserved targets of microRNAs

1 reference

12 December 2020

Disruption of Dicer1 induces dysregulated fetal gene expression and promotes hepatocarcinogenesis

1 reference

12 December 2020

Expression of reverse cholesterol transport proteins ATP-binding cassette A1 (ABCA1) and scavenger receptor BI (SR-BI) in the retina and retinal pigment epithelium

1 reference

12 December 2020

MicroRNA-125a-5p partly regulates the inflammatory response, lipid uptake, and ORP9 expression in oxLDL-stimulated monocyte/macrophages

1 reference

12 December 2020

Knockdown of FABP5 mRNA decreases cellular cholesterol levels and results in decreased apoB100 secretion and triglyceride accumulation in ARPE-19 cells

1 reference

12 December 2020

A human apoB100 transgenic mouse expresses human apoB100 in the RPE and develops features of early AMD.

1 reference

12 December 2020

Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration

1 reference

12 December 2020

Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC)

1 reference

12 December 2020

Development of apolipoprotein B antisense molecules as a therapy for hyperlipidemia

1 reference

12 December 2020

Abundant lipid and protein components of drusen

1 reference

12 December 2020

MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis

1 reference

12 December 2020

MiR-33 contributes to the regulation of cholesterol homeostasis.

1 reference

12 December 2020

miR-33 links SREBP-2 induction to repression of sterol transporters

1 reference

12 December 2020

MicroRNAs modulate the noncanonical transcription factor NF-kappaB pathway by regulating expression of the kinase IKKalpha during macrophage differentiation

1 reference

12 December 2020

miR-204 is required for lens and retinal development via Meis2 targeting

1 reference

12 December 2020

Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation

1 reference

12 December 2020

Evolution of reticular pseudodrusen

1 reference

12 December 2020

DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration

1 reference

12 December 2020

MiR-146a inhibits oxidized low-density lipoprotein-induced lipid accumulation and inflammatory response via targeting toll-like receptor 4

1 reference

12 December 2020

miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling

1 reference

12 December 2020

Advanced glycation endproduct changes to Bruch's membrane promotes lipoprotein retention by lipoprotein lipase

1 reference

12 December 2020

The oil spill in ageing Bruch membrane

1 reference

12 December 2020

Complement factor H binds malondialdehyde epitopes and protects from oxidative stress

1 reference

12 December 2020

Regulation of lipid metabolism by Dicer revealed through SILAC mice

1 reference

12 December 2020

Common micro RNAs (miRNAs) target complement factor H (CFH) regulation in Alzheimer's disease (AD) and in age-related macular degeneration (AMD)

1 reference

12 December 2020

Microphthalmia-associated transcription factor (MITF) promotes differentiation of human retinal pigment epithelium (RPE) by regulating microRNAs-204/211 expression

1 reference

12 December 2020

Spatial distribution of the pathways of cholesterol homeostasis in human retina

1 reference

12 December 2020

MicroRNA-27b is a regulatory hub in lipid metabolism and is altered in dyslipidemia

1 reference

12 December 2020

MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis

1 reference

12 December 2020

MicroRNAs 125a and 455 repress lipoprotein-supported steroidogenesis by targeting scavenger receptor class B type I in steroidogenic cells

1 reference

12 December 2020

Decreased membrane complement regulators in the retinal pigmented epithelium contributes to age-related macular degeneration

1 reference

12 December 2020

Subretinal drusenoid deposits in non-neovascular age-related macular degeneration: morphology, prevalence, topography, and biogenesis model

1 reference

12 December 2020

MicroRNAs 185, 96, and 223 repress selective high-density lipoprotein cholesterol uptake through posttranscriptional inhibition

1 reference

12 December 2020

MicroRNA-144 regulates hepatic ATP binding cassette transporter A1 and plasma high-density lipoprotein after activation of the nuclear receptor farnesoid X receptor

1 reference

12 December 2020

Lutein + Zeaxanthin and Omega-3 Fatty Acids for Age-Related Macular Degeneration

1 reference

12 December 2020

MicroRNA-30c reduces hyperlipidemia and atherosclerosis in mice by decreasing lipid synthesis and lipoprotein secretion

1 reference

12 December 2020

Elevated microRNA-34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT.

1 reference

12 December 2020

Inhibitory effect of microRNA-34a on retinal pigment epithelial cell proliferation and migration

1 reference

12 December 2020

Pretreatment with pyridoxamine mitigates isolevuglandin-associated retinal effects in mice exposed to bright light.

1 reference

12 December 2020

Mipomersen, an apolipoprotein B synthesis inhibitor, reduces atherogenic lipoproteins in patients with severe hypercholesterolemia at high cardiovascular risk: a randomized, double-blind, placebo-controlled trial

1 reference

12 December 2020

Identification of miR-185 as a regulator of de novo cholesterol biosynthesis and low density lipoprotein uptake

1 reference

12 December 2020

Altered miRNA expression in canine retinas during normal development and in models of retinal degeneration.

1 reference

12 December 2020

Subretinal drusenoid deposits: further characterization by lipid histochemistry

1 reference

12 December 2020

MicroRNA-27a/b regulates cellular cholesterol efflux, influx and esterification/hydrolysis in THP-1 macrophages

1 reference

12 December 2020

Elevated microRNA-155 promotes foam cell formation by targeting HBP1 in atherogenesis

1 reference

12 December 2020

Cholesterol in the retina: the best is yet to come.

1 reference

12 December 2020

Regulation of PPAR-alpha pathway by Dicer revealed through proteomic analysis.

1 reference

12 December 2020

microRNA regulation of lipoprotein metabolism.

1 reference

12 December 2020

A circulating microrna profile is associated with late-stage neovascular age-related macular degeneration

1 reference

12 December 2020

Evaluation of circulating miRNAs in wet age-related macular degeneration.

1 reference

12 December 2020

MicroRNA-223 coordinates cholesterol homeostasis

1 reference

12 December 2020

Mice that produce ApoB100 lipoproteins in the RPE do not develop drusen yet are still a valuable experimental system

1 reference

12 December 2020

Age-dependent increase in miRNA-34a expression in the posterior pole of the mouse eye

1 reference

12 December 2020

Identification of hydroxyapatite spherules provides new insight into subretinal pigment epithelial deposit formation in the aging eye

1 reference

12 December 2020

Comparison of Visual Function in Older Eyes in the Earliest Stages of Age-related Macular Degeneration to Those in Normal Macular Health

1 reference

12 December 2020

Regulation of age-related macular degeneration-like pathology by complement factor H.

1 reference

12 December 2020

A metabolic stress-inducible miR-34a-HNF4α pathway regulates lipid and lipoprotein metabolism

1 reference

12 December 2020

Serum MicroRNAs as Potential Biomarkers of AMD

1 reference

12 December 2020

The impact of microRNA gene regulation on the survival and function of mature cell types in the eye

1 reference

12 December 2020

MicroRNA-148a regulates LDL receptor and ABCA1 expression to control circulating lipoprotein levels

1 reference

12 December 2020

Genome-wide identification of microRNAs regulating cholesterol and triglyceride homeostasis

1 reference

12 December 2020

microRNA-33 Regulates ApoE Lipidation and Amyloid-β Metabolism in the Brain

1 reference

12 December 2020

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

1 reference

12 December 2020

MicroRNA Regulation of Atherosclerosis

1 reference

12 December 2020

MicroRNAs regulating apolipoprotein B-containing lipoprotein production

1 reference

12 December 2020

microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration

1 reference

12 December 2020

MicroRNA signatures in vitreous humour and plasma of patients with exudative AMD.

1 reference

12 December 2020

Regression of Some High-risk Features of Age-related Macular Degeneration (AMD) in Patients Receiving Intensive Statin Treatment

1 reference

12 December 2020

MicroRNAs in brain cholesterol metabolism and their implications for Alzheimer's disease

1 reference

12 December 2020

Increased Ocular Levels of MicroRNA-148a in Cases of Retinal Detachment Promote Epithelial-Mesenchymal Transition.

1 reference

12 December 2020

Lipids, oxidized lipids, oxidation-specific epitopes, and Age-related Macular Degeneration

1 reference

12 December 2020

An Eye on Age-Related Macular Degeneration: The Role of MicroRNAs in Disease Pathology.

1 reference

12 December 2020

Recombinant Haplotypes Narrow the ARMS2/HTRA1 Association Signal for Age-Related Macular Degeneration.

1 reference

12 December 2020

MicroRNA-processing Enzymes Are Essential for Survival and Function of Mature Retinal Pigmented Epithelial Cells in Mice

1 reference

12 December 2020

Subretinal Pigment Epithelial Deposition of Drusen Components Including Hydroxyapatite in a Primary Cell Culture Model

1 reference

12 December 2020

Correlation between miR-148 Expression in Vitreous and Severity of Rhegmatogenous Retinal Detachment.

1 reference

12 December 2020

Dissecting microRNA dysregulation in age-related macular degeneration: new targets for eye gene therapy

1 reference

12 December 2020

Circulating miRNAs as Potential Biomarkers of Age-Related Macular Degeneration.

1 reference

12 December 2020

MicroRNA Expression Patterns Involved in Amyloid Beta-Induced Retinal Degeneration

1 reference

12 December 2020

MicroRNAs and lipid metabolism.

1 reference

12 December 2020

miRNAs, single nucleotide polymorphisms (SNPs) and age-related macular degeneration (AMD).

1 reference

12 December 2020

Genetic variants in microRNAs and their binding sites within gene 3'UTRs associate with susceptibility to age-related macular degeneration.

1 reference

12 December 2020

Retinal pigment epithelium cholesterol efflux mediated by the 18 kDa translocator protein, TSPO, a potential target for treating age-related macular degeneration

1 reference

12 December 2020

Understanding AMD by analogy: systematic review of lipid-related common pathogenic mechanisms in AMD, AD, AS and GN.

1 reference

12 December 2020

Up-regulated Pro-inflammatory MicroRNAs (miRNAs) in Alzheimer's disease (AD) and Age-Related Macular Degeneration (AMD).

1 reference

12 December 2020

Differentially expressed microRNAs in the aqueous humor of patients with exfoliation glaucoma or primary open-angle glaucoma

1 reference

12 December 2020

10.1016/J.EXER.2018.09.023

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30292489%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30292489%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

PubMed publication ID

30292489

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30292489%20AND%20SRC:MED&resulttype=core&format=json