(Q56769911)

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Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants

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scholarly article

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Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants (English)

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genome-wide association study

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Alzheimer's disease

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based on heuristic

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Ricardo Segurado

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Ricardo Segurado

8

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Simon Lovestone

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Simon Lovestone

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object named as

Peter Holmans

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Michael C O'Donovan

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Michael O'Donovan

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Michael Gill

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Alison Goate

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Yonghong Li

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Carol Brayne

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Angharad Morgan

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Angharad Morgan

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Eric Schadt

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David C. Rubinsztein

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David Rubinsztein

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1

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Andrew Grupe

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Petra Nowotny

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Kristina M Tacey

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Kristina Tacey

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Paul Hollingworth

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Paul Hollingworth

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7

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Luke Jehu

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Joseph Catanese

14

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Joseph Catanese

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John Sninsky

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Brian Lawlor

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Leon Thal

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author name string

Richard Abraham

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Charles Rowland

4

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David Stone

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Maha Karnoub

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John C. Morris

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Michael J. Owen

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Julie Williams

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publication date

22 February 2007

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Human Molecular Genetics

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8

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865-873

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describes a project that uses

genome-wide association study

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based on heuristic

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Complete ascertainment of dementia in the Swedish Twin Registry: the HARMONY study

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https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

How heritable is Alzheimer's disease late in life? Findings from Swedish twins.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

Dynamin-binding protein gene on chromosome 10q is associated with late-onset Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

DAPK1 variants are associated with Alzheimer's disease and allele-specific expression

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

Complement factor H polymorphism in age-related macular degeneration

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

High-resolution whole-genome association study of Parkinson disease.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

Conflicting results regarding the semaphorin gene (SEMA5A) and the risk for Parkinson disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

Genomewide association, Parkinson disease, and PARK10

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

No evidence for association with Parkinson disease for 13 single-nucleotide polymorphisms identified by whole-genome association screening.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

A case-control association study of the 12 single-nucleotide polymorphisms implicated in Parkinson disease by a recent genome scan

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

Identification of four gene variants associated with myocardial infarction

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

Identification of two gene variants associated with risk of advanced fibrosis in patients with chronic hepatitis C.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

A full genome scan for late onset Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

Results of a high-resolution genome screen of 437 Alzheimer's disease families

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

Lysosomal processing of amyloid precursor protein to A beta peptides: a distinct role for cathepsin S

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

Positive and negative regulation of APP amyloidogenesis by sumoylation.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

Galanin/GALP and galanin receptors: role in central control of feeding, body weight/obesity and reproduction?

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

Galanin inhibits the potassium-evoked release of acetylcholine and the muscarinic receptor-mediated stimulation of phosphoinositide turnover in slices of monkey hippocampus

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

Galanin overexpressing transgenic mice

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

A confocal microscopic analysis of galaninergic hyperinnervation of cholinergic basal forebrain neurons in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

Galanin plasticity in the cholinergic basal forebrain in Alzheimer's disease and transgenic mice

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

Alpha1-antitrypsin deficiency--a model for conformational diseases

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

Promoter polymorphism in PCK1 (phosphoenolpyruvate carboxykinase gene) associated with type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

Characterization of the tyrosine kinase Tnk1 and its binding with phospholipase C-gamma1

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

Impaired phosphoinositide hydrolysis in Alzheimer's disease brain

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

Cholinergic and serotonergic stimulation of phosphoinositide hydrolysis is decreased in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

Phosphoinositide hydrolysis, G alpha q, phospholipase C, and protein kinase C in post mortem human brain: effects of post mortem interval, subject age, and Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

Muscarinic regulation of Alzheimer's disease amyloid precursor protein secretion and amyloid beta-protein production in human neuronal NT2N cells

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

High-throughput SNP allele-frequency determination in pooled DNA samples by kinetic PCR.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

Genetic association of the APP binding protein 2 gene (APBB2) with late onset Alzheimer disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

Molecular genetics of Alzheimer’s disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM031

21 January 2018

Identifiers

10.1093/HMG/DDM031

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