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(Q54991963)
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English
USPC-ARK-2
cell line
USPC ARK-2
USPC-ARK2
USC ARK-2
ARK-2
ARK2
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No label defined
No description defined
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Statements
instance of
cell line
1 reference
stated in
Cellosaurus release 49
retrieved
15 July 2024
Cellosaurus ID
CVCL_IV73
cancer cell line
1 reference
stated in
Cellosaurus release 49
retrieved
15 July 2024
Cellosaurus ID
CVCL_IV73
described by source
In vitro activity of pertuzumab in combination with trastuzumab in uterine serous papillary adenocarcinoma
1 reference
stated in
Cellosaurus release 49
retrieved
15 July 2024
Cellosaurus ID
CVCL_IV73
Uterine serous papillary carcinomas overexpress human trophoblast-cell-surface marker (Trop-2) and are highly sensitive to immunotherapy with hRS7, a humanized anti-Trop-2 monoclonal antibody
1 reference
stated in
Cellosaurus release 49
retrieved
15 July 2024
Cellosaurus ID
CVCL_IV73
Oncogenic PIK3CA gene mutations and HER2/neu gene amplifications determine the sensitivity of uterine serous carcinoma cell lines to GDC-0980, a selective inhibitor of Class I PI3 kinase and mTOR kinase (TORC1/2).
1 reference
stated in
Cellosaurus release 49
retrieved
15 July 2024
Cellosaurus ID
CVCL_IV73
PIK3CA oncogenic mutations represent a major mechanism of resistance to trastuzumab in HER2/neu overexpressing uterine serous carcinomas
1 reference
stated in
Cellosaurus release 49
retrieved
15 July 2024
Cellosaurus ID
CVCL_IV73
Afatinib demonstrates remarkable activity against HER2-amplified uterine serous endometrial cancer in vitro and in vivo.
1 reference
stated in
Cellosaurus release 49
retrieved
15 July 2024
Cellosaurus ID
CVCL_IV73
PIK3CA oncogenic mutations represent a major mechanism of resistance to trastuzumab in HER2/neu overexpressing uterine serous carcinomas
1 reference
stated in
Cellosaurus release 49
retrieved
15 July 2024
Cellosaurus ID
CVCL_IV73
Polymerase ε (POLE) ultra-mutation in uterine tumors correlates with T lymphocyte infiltration and increased resistance to platinum-based chemotherapy in vitro.
1 reference
stated in
Cellosaurus release 49
retrieved
15 July 2024
Cellosaurus ID
CVCL_IV73
established from medical condition
uterine corpus serous adenocarcinoma
1 reference
stated in
Cellosaurus release 26
retrieved
14 June 2018
Cellosaurus ID
CVCL_IV73
derived from organism type
Homo sapiens
sex or gender
female
1 reference
stated in
Cellosaurus release 49
retrieved
15 July 2024
Cellosaurus ID
CVCL_IV73
Identifiers
Cellosaurus ID
CVCL_IV73
1 reference
stated in
Cellosaurus release 49
retrieved
15 July 2024
Cellosaurus ID
CVCL_IV73
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