(Q54246031)

31 May 2018

title

Finding the missing links in EGFR. (English)

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31 May 2018

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31 May 2018

author name string

Nicholas J Bessman

series ordinal

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31 May 2018

publication date

5 January 2012

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31 May 2018

Nature Structural & Molecular Biology

published in

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31 May 2018

volume

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31 May 2018

issue

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31 May 2018

page(s)

1-3

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31 May 2018

Signal transduction by receptors with tyrosine kinase activity

cites work

1 reference

Regulation of the catalytic activity of the EGF receptor.

21 January 2018

1 reference

Cell signaling by receptor tyrosine kinases

21 January 2018

1 reference

An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors

21 January 2018

1 reference

An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor

21 January 2018

1 reference

Heterogeneity in EGF-binding affinities arises from negative cooperativity in an aggregating system

21 January 2018

1 reference

Structural Basis for Negative Cooperativity in Growth Factor Binding to an EGF Receptor

21 January 2018

1 reference

ErbB1 dimerization is promoted by domain co-confinement and stabilized by ligand binding

21 January 2018

1 reference

Simultaneous visualization of the extracellular and cytoplasmic domains of the epidermal growth factor receptor

21 January 2018

1 reference

Mechanistic insights into the activation of oncogenic forms of EGF receptor

21 January 2018

1 reference

In vitro enzymatic characterization of near full length EGFR in activated and inhibited states

21 January 2018

1 reference

Functional and structural stability of the epidermal growth factor receptor in detergent micelles and phospholipid nanodiscs.

21 January 2018

1 reference

Epidermal growth factor receptor mutations in lung cancer

21 January 2018

1 reference

Structural basis for inhibition of the epidermal growth factor receptor by cetuximab

21 January 2018

1 reference

Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface

21 January 2018

1 reference

Structural Evidence for Loose Linkage between Ligand Binding and Kinase Activation in the Epidermal Growth Factor Receptor

21 January 2018

1 reference

A unique structure for epidermal growth factor receptor bound to GW572016 (Lapatinib): relationships among protein conformation, inhibitor off-rate, and receptor activity in tumor cells

21 January 2018

1 reference

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

21 January 2018

1 reference

EGFR juxtamembrane domain, membranes, and calmodulin: kinetics of their interaction

21 January 2018

1 reference

Human epidermal growth factor receptor (EGFR) aligned on the plasma membrane adopts key features of Drosophila EGFR asymmetry

21 January 2018

1 reference

The Juxtamembrane Region of the EGF Receptor Functions as an Activation Domain

21 January 2018

1 reference

The membrane-proximal intracellular domain of the epidermal growth factor receptor underlies negative cooperativity in ligand binding

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22218287

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NSMB.2221

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31 May 2018

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31 May 2018