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English
Melanoma: What do all the mutations mean?
scientific article published on 17 April 2018
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1 reference
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Europe PubMed Central
PMC publication ID
6191351
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29663336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 March 2020
title
Melanoma: What do all the mutations mean?
(English)
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stated in
Europe PubMed Central
PMC publication ID
6191351
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29663336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 March 2020
author
Douglas B. Johnson
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2
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Europe PubMed Central
PMC publication ID
6191351
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29663336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 March 2020
Sunandana Chandra
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4
1 reference
stated in
Europe PubMed Central
PMC publication ID
6191351
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29663336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 March 2020
author name string
Elizabeth J Davis
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1
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Europe PubMed Central
PMC publication ID
6191351
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29663336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 March 2020
Jeffrey A Sosman
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3
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Europe PubMed Central
PMC publication ID
6191351
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29663336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 March 2020
language of work or name
English
0 references
publication date
17 April 2018
1 reference
stated in
Europe PubMed Central
PMC publication ID
6191351
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29663336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 March 2020
published in
Cancer
1 reference
stated in
Europe PubMed Central
PMC publication ID
6191351
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29663336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 March 2020
volume
124
1 reference
stated in
Europe PubMed Central
PMC publication ID
6191351
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29663336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 March 2020
issue
17
1 reference
stated in
Europe PubMed Central
PMC publication ID
6191351
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29663336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 March 2020
page(s)
3490-3499
1 reference
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Europe PubMed Central
PMC publication ID
6191351
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29663336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 March 2020
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Preexisting MEK1P124 mutations diminish response to BRAF inhibitors in metastatic melanoma patients.
1 reference
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7 January 2021
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BRAF(L597) mutations in melanoma are associated with sensitivity to MEK inhibitors
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7 January 2021
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Recurrent BRAF kinase fusions in melanocytic tumors offer an opportunity for targeted therapy
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7 January 2021
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Clinical activity of the MEK inhibitor trametinib in metastatic melanoma containing BRAF kinase fusion
1 reference
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7 January 2021
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Factors predictive of response, disease progression, and overall survival after dabrafenib and trametinib combination treatment: a pooled analysis of individual patient data from randomised trials
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7 January 2021
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Exome sequencing identifies recurrent mutations in NF1 and RASopathy genes in sun-exposed melanomas
1 reference
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https://api.crossref.org/works/10.1002%2FCNCR.31345
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7 January 2021
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Distinct sets of genetic alterations in melanoma
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Impact of NRAS mutations for patients with advanced melanoma treated with immune therapies
1 reference
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7 January 2021
based on heuristic
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Pathways and therapeutic targets in melanoma
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https://api.crossref.org/works/10.1002%2FCNCR.31345
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7 January 2021
based on heuristic
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Somatic activation of KIT in distinct subtypes of melanoma
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Crossref
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https://api.crossref.org/works/10.1002%2FCNCR.31345
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7 January 2021
based on heuristic
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BRAF mutations and KIT aberrations and their clinicopathological correlation in 202 Korean melanomas
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https://api.crossref.org/works/10.1002%2FCNCR.31345
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Phase II, open-label, single-arm trial of imatinib mesylate in patients with metastatic melanoma harboring c-Kit mutation or amplification
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Imatinib for melanomas harboring mutationally activated or amplified KIT arising on mucosal, acral, and chronically sun-damaged skin
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7 January 2021
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7 January 2021
based on heuristic
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Loss of NF1 in cutaneous melanoma is associated with RAS activation and MEK dependence
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Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCNCR.31345
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7 January 2021
based on heuristic
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BRAF/NRAS wild-type melanoma, NF1 status and sensitivity to trametinib
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Crossref
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https://api.crossref.org/works/10.1002%2FCNCR.31345
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7 January 2021
based on heuristic
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Phase II trial of MEK inhibitor selumetinib (AZD6244, ARRY-142886) in patients with BRAFV600E/K-mutated melanoma.
1 reference
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Crossref
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https://api.crossref.org/works/10.1002%2FCNCR.31345
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7 January 2021
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NF1-mutated melanoma tumors harbor distinct clinical and biological characteristics
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Crossref
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https://api.crossref.org/works/10.1002%2FCNCR.31345
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7 January 2021
based on heuristic
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Germline p16 mutations in familial melanoma
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https://api.crossref.org/works/10.1002%2FCNCR.31345
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7 January 2021
based on heuristic
inferred from DOI database lookup
Genome-wide association study identifies three loci associated with melanoma risk
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7 January 2021
based on heuristic
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Fine mapping of genetic susceptibility loci for melanoma reveals a mixture of single variant and multiple variant regions
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Crossref
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https://api.crossref.org/works/10.1002%2FCNCR.31345
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7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of CDKN2A expression is a frequent event in primary invasive melanoma and correlates with sensitivity to the CDK4/6 inhibitor PD0332991 in melanoma cell lines
1 reference
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Crossref
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https://api.crossref.org/works/10.1002%2FCNCR.31345
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7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy.
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https://api.crossref.org/works/10.1002%2FCNCR.31345
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7 January 2021
based on heuristic
inferred from DOI database lookup
The RAC1 P29S hotspot mutation in melanoma confers resistance to pharmacological inhibition of RAF
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7 January 2021
based on heuristic
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RAC1 P29S regulates PD-L1 expression in melanoma.
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7 January 2021
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TERT promoter mutation status as an independent prognostic factor in cutaneous melanoma
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Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCNCR.31345
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCNCR.31345
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparative analysis of the GNAQ, GNA11, SF3B1, and EIF1AX driver mutations in melanoma and across the cancer spectrum.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCNCR.31345
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RasGRP3 Mediates MAPK Pathway Activation in GNAQ Mutant Uveal Melanoma.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCNCR.31345
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of selumetinib vs chemotherapy on progression-free survival in uveal melanoma: a randomized clinical trial
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCNCR.31345
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of 8q24 copy number gains and c-MYC expression in amelanotic cutaneous melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCNCR.31345
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MYC regulates the antitumor immune response through CD47 and PD-L1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCNCR.31345
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCNCR.31345
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A landscape of driver mutations in melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCNCR.31345
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BRAF oncogenic mutations correlate with progression rather than initiation of human melanoma.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/29663336
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
BRAF inhibitor activity in V600R metastatic melanoma--response.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/29663336
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1002/CNCR.31345
1 reference
stated in
Europe PubMed Central
PMC publication ID
6191351
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29663336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 March 2020
PMC publication ID
6191351
1 reference
stated in
Europe PubMed Central
PMC publication ID
6191351
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29663336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 March 2020
PubMed publication ID
29663336
1 reference
stated in
Europe PubMed Central
PMC publication ID
6191351
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29663336%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 March 2020
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