(Q53644203)

16 May 2018

title

The Rae1-Nup98 complex prevents aneuploidy by inhibiting securin degradation. (English)

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16 May 2018

Jan M van Deursen

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16 May 2018

author name string

Karthik B Jeganathan

series ordinal

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16 May 2018

Liviu Malureanu

series ordinal

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16 May 2018

language of work or name

English

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publication date

1 December 2005

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16 May 2018

published in

Nature

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16 May 2018

volume

438

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16 May 2018

issue

7070

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16 May 2018

page(s)

1036-1039

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16 May 2018

The anaphase-promoting complex: proteolysis in mitosis and beyond

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04221

Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04221

RAE1 is a shuttling mRNA export factor that binds to a GLEBS-like NUP98 motif at the nuclear pore complex through multiple domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04221

The mitotic checkpoint protein hBUB3 and the mRNA export factor hRAE1 interact with GLE2p-binding sequence (GLEBS)-containing proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04221

The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04221

Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04221

Identification and characterization of nuclear pore subcomplexes in mitotic extract of human somatic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04221

A Rae1-containing ribonucleoprotein complex is required for mitotic spindle assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04221

Dominant-negative cyclin-selective ubiquitin carrier protein E2-C/UbcH10 blocks cells in metaphase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04221

Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04221

Securin is required for chromosomal stability in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04221

Securin is not required for cellular viability, but is required for normal growth of mouse embryonic fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04221

Securin degradation is mediated by fzy and fzr, and is required for complete chromatid separation but not for cytokinesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04221

21 January 2018

Recycling the Cell Cycle

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04221

Regulation of APC activity by phosphorylation and regulatory factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04221

Mitotic regulation of the APC activator proteins CDC20 and CDH1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04221

Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04221

CREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04221

BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04221

Substrate recognition by the Cdc20 and Cdh1 components of the anaphase-promoting complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04221

Overexpressed pituitary tumor-transforming gene causes aneuploidy in live human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04221

21 January 2018

Identifiers

DOI

10.1038/NATURE04221

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16 May 2018

Dimensions Publication ID

1034456069

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1 reference

16 May 2018