(Q53415989)

14 May 2018

title

Amyloid efflux transporter expression at the blood-brain barrier declines in normal aging. (English)

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14 May 2018

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14 May 2018

Conrad E Johanson

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Gerald D Silverberg

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14 May 2018

Arthur A Messier

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14 May 2018

Miles C Miller

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14 May 2018

Samir S Majmudar

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14 May 2018

Edward G Stopa

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14 May 2018

John E Donahue

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14 May 2018

publication date

1 October 2010

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14 May 2018

Journal of Neuropathology & Experimental Neurology

published in

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14 May 2018

volume

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14 May 2018

issue

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14 May 2018

page(s)

1034-1043

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14 May 2018

Clearing amyloid through the blood-brain barrier

cites work

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Relationship of senescence of cerebrospinal fluid circulatory system to dementias of the aged

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Alzheimer's disease, normal-pressure hydrocephalus, and senescent changes in CSF circulatory physiology: a hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

RAGE, LRP-1, and amyloid-beta protein in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Hippocampal RAGE immunoreactivity in early and advanced Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Metabolic regulation of brain Abeta by neprilysin

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Human neprilysin is capable of degrading amyloid beta peptide not only in the monomeric form but also the pathological oligomeric form

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Clearance of amyloid beta-peptide from brain: transport or metabolism?

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Pathology of cerebrospinal fluid and interstitial fluid of the CNS: significance for Alzheimer disease, prion disorders and multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Transport pathways for clearance of human Alzheimer's amyloid beta-peptide and apolipoproteins E and J in the mouse central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Amyloid deposition and influx transporter expression at the blood-brain barrier increase in normal aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Amyloid and Tau accumulate in the brains of aged hydrocephalic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

The low density lipoprotein receptor-related protein 1 mediates uptake of amyloid beta peptides in an in vitro model of the blood-brain barrier cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

beta-Amyloid efflux mediated by p-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

LRP: a multifunctional scavenger and signaling receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Modulation of amyloid beta-protein clearance and Alzheimer's disease susceptibility by the LDL receptor-related protein pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Deposition of Alzheimer's beta-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Gene regulation and DNA damage in the ageing human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

The cerebrospinal fluid production rate is reduced in dementia of the Alzheimer's type.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Light microscopic image analysis system to quantify immunoreactive terminal area apposed to nerve cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Cerebral cortical arteriolar angiopathy, vascular beta-amyloid, smooth muscle actin, Braak stage, and APOE genotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Expression of drug transporters at the blood-brain barrier using an optimized isolated rat brain microvessel strategy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

A hundred years of Alzheimer's disease research

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Substitution at codon 22 reduces clearance of Alzheimer's amyloid-beta peptide from the cerebrospinal fluid and prevents its transport from the central nervous system into blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Distribution of Alzheimer-type pathologic changes in nondemented elderly individuals matches the pattern in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Alzheimer neuropathologic alterations in aged cognitively normal subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

The effect of age on P-glycoprotein expression and function in the Fischer-344 rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

The LDL receptor gene family: signaling functions during development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Coaxing the LDL receptor family into the fold.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Diverse role of LDL receptor-related protein in the clearance of proteases and in signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Functional role of lipoprotein receptors in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Comparison of replicative senescence and stress-induced premature senescence combining differential display and low-density DNA arrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Downregulation of LRP1 [correction of LPR1] at the blood-brain barrier in streptozotocin-induced diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Protein kinase C-alpha-mediated regulation of low-density lipoprotein receptor related protein and urokinase increases astrocytoma invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Proteomic analysis of GLUT4 storage vesicles reveals LRP1 to be an important vesicle component and target of insulin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Characterization and functional analysis of the promoter of RAGE, the receptor for advanced glycation end products

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Decrease with age in methylcytosines in the promoter region of receptor for advanced glycated end products (RAGE) gene in autopsy human cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Epigenetic regulation in the pathophysiology of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Modulation of P-glycoprotein function by sphingosine kinase-1 in brain endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Functional induction of P-glycoprotein in the blood-brain barrier of streptozotocin-induced diabetic rats: evidence for the involvement of nuclear factor-kappaB, a nitrosative stress-sensitive transcription factor, in the regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

T lymphocytes impair P-glycoprotein function during neuroinflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

Vascular abnormalities: the insidious pathogenesis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181F46E25

10.1097/NEN.0B013E3181F46E25

21 January 2018

Identifiers

DOI

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Fatcat

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Fatcat ID

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Fatcat

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mapped directly with Wikidata item

30 July 2022

based on heuristic

https://api.fatcat.wiki/v0/release/6qy7vwgwk5bcbjkkfv24lyeupm

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