(Q53238389)

English

Caspase-3 activation and inflammatory responses in rat hippocampus inoculated with a recombinant adenovirus expressing the Alzheimer amyloid precursor protein.

scientific article published in September 2000

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scholarly article

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Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/11038254

Caspase-3 activation and inflammatory responses in rat hippocampus inoculated with a recombinant adenovirus expressing the Alzheimer amyloid precursor protein. (English)

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/11038254

1 reference

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inferred from title

author name string

M Masumura

1

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/11038254

R Hata

2

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/11038254

I Nishimura

3

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/11038254

T Uetsuki

4

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/11038254

T Sawada

5

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/11038254

K Yoshikawa

6

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/11038254

publication date

1 September 2000

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/11038254

Molecular Brain Research

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/11038254

80

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/11038254

2

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/11038254

219-227

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/11038254

Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E.

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Overexpression in neurons of human presenilin-1 or a presenilin-1 familial Alzheimer disease mutant does not enhance apoptosis.

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Adenovirus gene transfer causes inflammation in the brain

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Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: implications for clinical trials

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The importance of inflammatory mechanisms for the development of Alzheimer's disease

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Inflammatory pathogenesis in Alzheimer's disease: biological mechanisms and cognitive sequeli

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Microglia: Intrinsic immuneffector cell of the brain

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Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation

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Interleukin-1 expression in different plaque types in Alzheimer's disease: significance in plaque evolution.

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Activation of caspase-3 in beta-amyloid-induced apoptosis of cultured rat cortical neurons

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The immunohistochemical demonstration of subsequences of the precursor of the amyloid A4 protein in senile plaques in Alzheimer's disease.

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A simple and efficient method for purification of infectious recombinant adenovirus.

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The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

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Apoptotic pathways mobilized in microglia and neurones as a consequence of chromogranin A-induced microglial activation

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Detection of activated Caspase-3 by a cleavage site-directed antiserum during naturally occurring DRG neurons apoptosis

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Microglia: a sensor for pathological events in the CNS

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Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer's disease

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A second cytotoxic proteolytic peptide derived from amyloid beta-protein precursor

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The long term adenoviral expression of the human amyloid precursor protein shows different secretase activities in rat cortical neurons and astrocytes.

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Activation of microglial cells by beta-amyloid protein and interferon-gamma.

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Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome

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Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

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7 January 2021

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Degeneration in vivo of rat hippocampal neurons by wild-type Alzheimer amyloid precursor protein overexpressed by adenovirus-mediated gene transfer.

1 reference

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7 January 2021

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Alternative, non-secretase processing of Alzheimer's beta-amyloid precursor protein during apoptosis by caspase-6 and -8.

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Neuroglial activation repertoire in the injured brain: graded response, molecular mechanisms and cues to physiological function

1 reference

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Microglial activation in early stages of amyloid β protein deposition

1 reference

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Normal and abnormal biology of the beta-amyloid precursor protein

1 reference

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In situ immunodetection of neuronal caspase-3 activation in Alzheimer disease

1 reference

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Reactive microglia/macrophages phagocytose amyloid precursor protein produced by neurons following neural damage.

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A predominant apoptotic death pathway of neuronal PC12 cells induced by activated microglia is displaced by a non-apoptotic death pathway following blockage of caspase-3-dependent cascade

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Caspase-2 mediates neuronal cell death induced by beta-amyloid

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Identifiers

10.1016/S0169-328X(00)00163-7

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/11038254

release_ukrc4dmwprhpdffcfaqc43f2qi

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24 November 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/11038254

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