(Q53220635)

12 May 2018

title

Design of phase II ALS clinical trials. (English)

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12 May 2018

amyotrophic lateral sclerosis

main subject

phase II clinical trial

0 references

1 reference

Merit Cudkowicz

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12 May 2018

author name string

David A Schoenfeld

series ordinal

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12 May 2018

publication date

1 January 2008

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12 May 2018

Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders

published in

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12 May 2018

volume

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12 May 2018

issue

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12 May 2018

page(s)

16-23

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12 May 2018

Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity

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1 reference

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A randomized, placebo-controlled trial of topiramate in amyotrophic lateral sclerosis

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A two-stage design for a phase II clinical trial of coenzyme Q10 in ALS.

21 January 2018

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1 reference

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21 January 2018

1 reference

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Pro/con clinical debate: It is acceptable to stop large multicentre randomized controlled trials at interim analysis for futility. Pro: Futility stopping can speed up the development of effective treatments

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The ALSFRS-R: a revised ALS functional rating scale that incorporates assessments of respiratory function. BDNF ALS Study Group (Phase III).

21 January 2018

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Functional outcome measures as clinical trial endpoints in ALS.

21 January 2018

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A clinical trial of creatine in ALS.

21 January 2018

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21 January 2018

Identifiers

DOI

1 reference

12 May 2018

1 reference

12 May 2018