(Q53257766)

12 May 2018

title

TCF1 links GIPR signaling to the control of beta cell function and survival. (English)

1 reference

12 May 2018

1 reference

12 May 2018

Daniel J. Drucker

Daniel J Drucker

1 reference

12 May 2018

Jeffrey L. Wrana

Jeffrey L Wrana

1 reference

12 May 2018

Erin E Mulvihill

Erin E Mulvihill

1 reference

12 May 2018

John R Ussher

John R Ussher

1 reference

12 May 2018

author name string

Jelena Kolic

1 reference

12 May 2018

Laurie L Baggio

1 reference

12 May 2018

Xiemen Cao

1 reference

12 May 2018

Yu Liu

1 reference

12 May 2018

Benjamin J Lamont

1 reference

12 May 2018

Tsukasa Morii

1 reference

12 May 2018

Catherine J Streutker

1 reference

12 May 2018

Natalia Tamarina

1 reference

12 May 2018

Louis H Philipson

1 reference

12 May 2018

Patrick E MacDonald

1 reference

12 May 2018

language of work or name

English

0 references

publication date

7 December 2015

1 reference

12 May 2018

published in

Nature Medicine

1 reference

12 May 2018

volume

1 reference

12 May 2018

issue

1 reference

12 May 2018

page(s)

84-90

1 reference

12 May 2018

A novel human-based receptor antagonist of sustained action reveals body weight control by endogenous GLP-1.

cites work

1 reference

12 December 2020

Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide 1 receptor gene.

1 reference

12 December 2020

Diminished pancreatic beta-cell mass in securin-null mice is caused by beta-cell apoptosis and senescence

1 reference

12 December 2020

Insulin treatment and high-fat diet feeding reduces the expression of three Tcf genes in rodent pancreas

1 reference

12 December 2020

Hyperinsulinemia drives diet-induced obesity independently of brain insulin production

1 reference

12 December 2020

Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic beta-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and dow

1 reference

12 December 2020

An HMG-box-containing T-cell factor required for thymocyte differentiation.

1 reference

12 December 2020

Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes

1 reference

12 December 2020

Glucose intolerance caused by a defect in the entero-insular axis: a study in gastric inhibitory polypeptide receptor knockout mice

1 reference

12 December 2020

Glucose-dependent insulinotropic polypeptide receptor null mice exhibit compensatory changes in the enteroinsular axis.

1 reference

12 December 2020

Pancreatic GLP-1 receptor activation is sufficient for incretin control of glucose metabolism in mice.

1 reference

12 December 2020

Inhibition of gastric inhibitory polypeptide signaling prevents obesity

1 reference

12 December 2020

Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

1 reference

12 December 2020

Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function

1 reference

12 December 2020

TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program

1 reference

12 December 2020

Enhanced glucose-dependent insulinotropic polypeptide secretion and insulinotropic action in glucagon-like peptide 1 receptor -/- mice

1 reference

12 December 2020

Pharmacology, physiology, and mechanisms of incretin hormone action

1 reference

12 December 2020

RETRACTED: Transcription factor 7-like 2 regulates beta-cell survival and function in human pancreatic islets

1 reference

12 December 2020

Differential antidiabetic efficacy of incretin agonists versus DPP-4 inhibition in high fat fed mice

1 reference

12 December 2020

International Union of Pharmacology. XXXV. The glucagon receptor family

1 reference

12 December 2020

Phenotypic Characterization of MIP-CreERT1Lphi Mice With Transgene-Driven Islet Expression of Human Growth Hormone

1 reference

12 December 2020

The beta-catenin--TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survival

1 reference

12 December 2020

A polymorphism in the TCF7 gene, C883A, is associated with type 1 diabetes

1 reference

12 December 2020

Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand

1 reference

12 December 2020

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

1 reference

12 December 2020

Dual elimination of the glucagon and GLP-1 receptors in mice reveals plasticity in the incretin axis

1 reference

12 December 2020

A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents

1 reference

12 December 2020

GLP-1 receptor agonists for individualized treatment of type 2 diabetes mellitus

1 reference

12 December 2020

GLP-1 receptor activation improves beta cell function and survival following induction of endoplasmic reticulum stress

1 reference

12 December 2020

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

1 reference

12 December 2020

Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus

1 reference

12 December 2020

Pituitary tumor-transforming gene: physiology and implications for tumorigenesis

1 reference

12 December 2020

Pituitary tumor transforming gene-null male mice exhibit impaired pancreatic beta cell proliferation and diabetes

1 reference

12 December 2020

Differential importance of glucose-dependent insulinotropic polypeptide vs glucagon-like peptide 1 receptor signaling for beta cell survival in mice

1 reference

12 December 2020

Unimolecular dual incretins maximize metabolic benefits in rodents, monkeys, and humans.

1 reference

12 December 2020

Pharmacology, physiology, and mechanisms of action of dipeptidyl peptidase-4 inhibitors

1 reference

12 December 2020

Elevated Hepatic miR-22-3p Expression Impairs Gluconeogenesis by Silencing the Wnt-Responsive Transcription Factor Tcf7.

1 reference

12 December 2020

Extensive alternative splicing and dual promoter usage generate Tcf-1 protein isoforms with differential transcription control properties

1 reference

12 December 2020

Pleiotropic effects of GIP on islet function involve osteopontin

1 reference

12 December 2020

Conditional gene targeting in mouse pancreatic ß-Cells: analysis of ectopic Cre transgene expression in the brain.

1 reference

12 December 2020

Impaired islet function in commonly used transgenic mouse lines due to human growth hormone minigene expression.

1 reference

12 December 2020

Evidence for association of the TCF7 locus with type I diabetes.

1 reference

12 December 2020

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

1 reference

12 December 2020

Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis

1 reference

12 December 2020

Increased GIP signaling induces adipose inflammation via a HIF-1α-dependent pathway and impairs insulin sensitivity in mice

1 reference

12 December 2020

Identifiers

DOI

10.1038/NM.3997

1 reference

12 May 2018

1 reference

12 May 2018