(Q53195350)

12 May 2018

title

Somatic MED12 mutations in prostate cancer and uterine leiomyomas promote tumorigenesis through distinct mechanisms. (English)

1 reference

12 May 2018

1 reference

12 May 2018

Tapio Visakorpi

1 reference

12 May 2018

Markku Varjosalo

1 reference

12 May 2018

Mikko Turunen

0 references

Netta Mäkinen

0 references

Salla Keskitalo

0 references

Tuomas Heikkinen

0 references

Heli Nevanlinna

1 reference

12 May 2018

Jukka-Pekka Mecklin

1 reference

12 May 2018

Heikki Järvinen

1 reference

12 May 2018

author name string

Kati Kämpjärvi

1 reference

12 May 2018

Nam Hee Kim

1 reference

12 May 2018

Alison D Clark

1 reference

12 May 2018

Pernilla von Nandelstadh

1 reference

12 May 2018

Min Ju Park

1 reference

12 May 2018

Kati Kivinummi

1 reference

12 May 2018

Susanna Lintula

1 reference

12 May 2018

Kristina Hotakainen

1 reference

12 May 2018

Tom Böhling

1 reference

12 May 2018

Ralf Bützow

1 reference

12 May 2018

Jan Böhm

1 reference

12 May 2018

Mika Kontro

1 reference

12 May 2018

Jussi Taipale

1 reference

12 May 2018

Thomas G Boyer

1 reference

12 May 2018

Pia Vahteristo

1 reference

12 May 2018

publication date

18 September 2015

1 reference

12 May 2018

published in

The Prostate

1 reference

12 May 2018

volume

1 reference

12 May 2018

issue

1 reference

12 May 2018

page(s)

22-31

1 reference

12 May 2018

The human Mediator complex: a versatile, genome-wide regulator of transcription

cites work

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

Function and regulation of the Mediator complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

Origins and activity of the Mediator complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

Comparative genomics supports a deep evolutionary origin for the large, four-module transcriptional mediator complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

CDK8: a positive regulator of transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

Mutations in Exon 1 highlight the role of MED12 in uterine leiomyomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

Characterization of uterine leiomyomas by whole-genome sequencing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

Uterine leiomyoma-linked MED12 mutations disrupt mediator-associated CDK activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

Mutational analysis of MED12 exon 2 in uterine leiomyoma and other common tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

Somatic MED12 mutations in uterine leiomyosarcoma and colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

MED12 alterations in both human benign and malignant uterine soft tissue tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

MED12 mutations in leiomyosarcoma and extrauterine leiomyoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

Exome sequencing identifies highly recurrent MED12 somatic mutations in breast fibroadenoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

Somatic MED12 mutations are associated with poor prognosis markers in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

Next-Gen Sequencing Exposes Frequent MED12 Mutations and Actionable Therapeutic Targets in Phyllodes Tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

The protein interaction landscape of the human CMGC kinase group

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

Mutations in MED12 cause X-linked Ohdo syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

Mediator is a transducer of Wnt/beta-catenin signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

A coregulatory role for the TRAP-mediator complex in androgen receptor-mediated gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

Regulation of androgen receptor-dependent transcription by coactivator MED1 is mediated through a newly discovered noncanonical binding motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

A coregulatory role for the mediator complex in prostate cancer cell proliferation and gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

ERK and AKT signaling drive MED1 overexpression in prostate cancer in association with elevated proliferation and tumorigenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

MED15, encoding a subunit of the mediator complex, is overexpressed at high frequency in castration-resistant prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

MED12 overexpression is a frequent event in castration-resistant prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

Epithelial-mesenchymal transitions in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

TGFβ-induced invasion of prostate cancer cells is promoted by c-Jun-dependent transcriptional activation of Snail1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

Stromal TGF-β signaling induces AR activation in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

The mutational landscape of lethal castration-resistant prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

The mitochondrial and autosomal mutation landscapes of prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

Lack of evidence for frequent MED12 p.L1224F mutation in prostate tumours from Caucasian patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

COSMIC: exploring the world's knowledge of somatic mutations in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

Discovery and saturation analysis of cancer genes across 21 tumour types

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23092

21 January 2018

Identifiers

DOI

10.1002/PROS.23092

1 reference

12 May 2018

1 reference

12 May 2018