(Q53161544)

12 May 2018

title

Zebularine inhibits the growth of HeLa cervical cancer cells via cell cycle arrest and caspase-dependent apoptosis. (English)

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12 May 2018

main subject

cervix uterine cancer

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Bo Ra You

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12 May 2018

Woo Hyun Park

series ordinal

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12 May 2018

publication date

21 June 2012

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12 May 2018

Molecular Biology Reports

published in

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12 May 2018

volume

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12 May 2018

issue

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12 May 2018

page(s)

9723-9731

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12 May 2018

General transcription factor binding at CpG islands in normal cells correlates with resistance to de novo DNA methylation in cancer cells

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ZIC1 is downregulated through promoter hypermethylation, and functions as a tumor suppressor gene in colorectal cancer

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The tobacco-specific carcinogen NNK induces DNA methyltransferase 1 accumulation and tumor suppressor gene hypermethylation in mice and lung cancer patients

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DNA methylation profiling reveals novel biomarkers and important roles for DNA methyltransferases in prostate cancer

21 January 2018

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Overexpression of DNA methyltransferases 1, 3a, and 3b significantly correlates with retinoblastoma tumorigenesis

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Biological rationale for the use of DNA methyltransferase inhibitors as new strategy for modulation of tumor response to chemotherapy and radiation

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The application of delivery systems for DNA methyltransferase inhibitors

21 January 2018

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New ways to use DNA methyltransferase inhibitors for the treatment of myelodysplastic syndrome

21 January 2018

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The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells

21 January 2018

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Epigenetic changes by zebularine leading to enhanced differentiation of human promyelocytic leukemia NB4 and KG1 cells

21 January 2018

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5-Aza-2'-deoxycytidine is a potent inhibitor of DNA methyltransferase 3B and induces apoptosis in human endometrial cancer cell lines with the up-regulation of hMLH1.

21 January 2018

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Re-differentiation of thyroid carcinoma cell lines treated with 5-Aza-2'-deoxycytidine and retinoic acid.

21 January 2018

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Potentiation of reactive oxygen species is a marker for synergistic cytotoxicity of MS-275 and 5-azacytidine in leukemic cells

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21 January 2018

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21 January 2018

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Genetic and epigenetic changes of HPV16 in cervical cancer differentially regulate E6/E7 expression and associate with disease progression

21 January 2018

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Comparison of DNA hypermethylation patterns in different types of uterine cancer: cervical squamous cell carcinoma, cervical adenocarcinoma and endometrial adenocarcinoma.

21 January 2018

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Metabolic activation of zebularine, a novel DNA methylation inhibitor, in human bladder carcinoma cells

21 January 2018

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Effects of a novel DNA methyltransferase inhibitor zebularine on human breast cancer cells

21 January 2018

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21 January 2018

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21 January 2018

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Development of DNA methyltransferase inhibitors for the treatment of neoplastic diseases

21 January 2018

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Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells

21 January 2018

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Glutathione depletion causes cell growth inhibition and enhanced apoptosis in pancreatic cancer cells

21 January 2018

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Enhancement of carboplatin-mediated lung cancer cell killing by simultaneous disruption of glutathione and thioredoxin metabolism.

21 January 2018

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Caspase inhibitor decreases apoptosis in pyrogallol-treated lung cancer Calu-6 cells via the prevention of GSH depletion.

21 January 2018

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12 December 2020

Effects of DNA methylation on the structure of nucleosomes

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12 December 2020

Inhibition of DNA methyltransferase induces G2 cell cycle arrest and apoptosis in human colorectal cancer cells via inhibition of JAK2/STAT3/STAT5 signalling

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12 December 2020

The DNA methyltransferase inhibitors zebularine and decitabine induce mitochondria‐mediated apoptosis and DNA damage in p53 mutant leukemic T cells

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12 December 2020

DNA methylation imprinting marks and DNA methyltransferase expression in human spermatogenic cell stages

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12 December 2020

Chrysin enhances doxorubicin-induced cytotoxicity in human lung epithelial cancer cell lines: the role of glutathione

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12 December 2020

Arsenic trioxide-mediated growth inhibition in MC/CAR myeloma cells via cell cycle arrest in association with induction of cyclin-dependent kinase inhibitor, p21, and apoptosis

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12 December 2020

DNA methyltransferase DNMT3b protein overexpression as a prognostic factor in patients with diffuse large B-cell lymphomas

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12 December 2020

Role of the DNA methyltransferase variant DNMT3b3 in DNA methylation.

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12 December 2020

10.1007/S11033-012-1837-Z

Identifiers

DOI

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12 May 2018

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12 May 2018