(Q52594636)

4 May 2018

title

Imaging transforming growth factor-beta signaling dynamics and therapeutic response in breast cancer bone metastasis. (English)

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4 May 2018

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Yibin Kang

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4 May 2018

author name string

Manav Korpal

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4 May 2018

Jun Yan

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4 May 2018

Xin Lu

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4 May 2018

Shuwa Xu

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4 May 2018

Dorothy A Lerit

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4 May 2018

language of work or name

English

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publication date

13 July 2009

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4 May 2018

published in

Nature Medicine

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4 May 2018

volume

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4 May 2018

issue

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4 May 2018

page(s)

960-966

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4 May 2018

Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.1943

Global analysis of Smad2/3-dependent TGF-beta signaling in living mice reveals prominent tissue-specific responses to injury

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.1943

Metastasis to bone: causes, consequences and therapeutic opportunities

21 January 2018

1 reference

12 December 2020

Modulation of type beta transforming growth factor activity in bone cultures by osteotropic hormones

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12 December 2020

Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway

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12 December 2020

Optimization of a dihydropyrrolopyrazole series of transforming growth factor-beta type I receptor kinase domain inhibitors: discovery of an orally bioavailable transforming growth factor-beta receptor type I inhibitor as antitumor agent

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12 December 2020

Imaging cancer dynamics in vivo at the tumor and cellular level with fluorescent proteins

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12 December 2020

Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta

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12 December 2020

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12 December 2020

LY2109761, a novel transforming growth factor beta receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis

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12 December 2020

Pamidronate prevents the development of skeletal metastasis in nude mice transplanted with human breast cancer cells by reducing tumor burden within bone.

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12 December 2020

Mechanisms of bone metastasis

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12 December 2020

Micro-CT combined with bioluminescence imaging: a dynamic approach to detect early tumor-bone interaction in a tumor osteolysis murine model

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12 December 2020

Targeting the TGF beta signaling network in human neoplasia

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12 December 2020

In vivo imaging of molecular-genetic targets for cancer therapy

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12 December 2020

Tumour microenvironment: TGFbeta: the molecular Jekyll and Hyde of cancer

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12 December 2020

A multigenic program mediating breast cancer metastasis to bone

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12 December 2020

Reduction in new metastases in breast cancer with adjuvant clodronate treatment

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12 December 2020

Interference with the microenvironmental support impairs the de novo formation of bone metastases in vivo

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12 December 2020

Multimodality imaging of tumor xenografts and metastases in mice with combined small-animal PET, small-animal CT, and bioluminescence imaging

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12 December 2020

Development of TGF-beta signalling inhibitors for cancer therapy

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12 December 2020

Oral ibandronate for the treatment of metastatic bone disease in breast cancer: efficacy and safety results from a randomized, double-blind, placebo-controlled trial

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12 December 2020

Proteolysis of latent transforming growth factor-beta (TGF-beta )-binding protein-1 by osteoclasts. A cellular mechanism for release of TGF-beta from bone matrix.

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12 December 2020

TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4

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12 December 2020

Oral ibandronate reduces the risk of skeletal complications in breast cancer patients with metastatic bone disease: results from two randomised, placebo-controlled phase III studies

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12 December 2020

High dose pamidronate: clinical and biochemical effects in metastatic bone disease.

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12 December 2020

Human Smad3 and Smad4 are sequence-specific transcription activators

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12 December 2020

Spying on cancer: molecular imaging in vivo with genetically encoded reporters

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12 December 2020

Molecular mechanisms of breast cancer metastases to bone

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12 December 2020

On the horizon: can bisphosphonates prevent bone metastases?

1 reference

12 December 2020

Bisphosphonates: an update on mechanisms of action and how these relate to clinical efficacy

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12 December 2020

Imaging tri-fusion multimodality reporter gene expression in living subjects

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12 December 2020

The tumor-suppressive functions of the human INK4A locus

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12 December 2020

TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development

1 reference

12 December 2020

Activated type I TGFbeta receptor kinase enhances the survival of mammary epithelial cells and accelerates tumor progression

1 reference

12 December 2020

Identifiers

DOI

10.1038/NM.1943

1 reference

4 May 2018

release_rutpkre5ubgbrauxq36zfk7gni

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/rutpkre5ubgbrauxq36zfk7gni

24 November 2022

mapped directly with Wikidata item

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4 May 2018