(Q52132111)

English

Formycin A and its N-methyl analogues, specific inhibitors of E. coli purine nucleoside phosphorylase (PNP): induced tautomeric shifts on binding to enzyme, and enzyme-->ligand fluorescence resonance energy transfer.

scientific article published in January 2000

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Europe PubMed Central

PubMed publication ID

22 April 2018

http://europepmc.org/abstract/MED/10606773

Formycin A and its N-methyl analogues, specific inhibitors of E. coli purine nucleoside phosphorylase (PNP): induced tautomeric shifts on binding to enzyme, and enzyme-->ligand fluorescence resonance energy transfer. (English)

1 reference

Europe PubMed Central

PubMed publication ID

22 April 2018

http://europepmc.org/abstract/MED/10606773

Escherichia coli

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Jacek Wierzchowski

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J Wierzchowski

3

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author name string

B Kierdaszuk

1

1 reference

Europe PubMed Central

PubMed publication ID

22 April 2018

http://europepmc.org/abstract/MED/10606773

A Modrak-Wójcik

2

1 reference

Europe PubMed Central

PubMed publication ID

22 April 2018

http://europepmc.org/abstract/MED/10606773

D Shugar

4

1 reference

Europe PubMed Central

PubMed publication ID

22 April 2018

http://europepmc.org/abstract/MED/10606773

publication date

1 January 2000

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Europe PubMed Central

PubMed publication ID

22 April 2018

http://europepmc.org/abstract/MED/10606773

Biochimica et Biophysica Acta

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Europe PubMed Central

PubMed publication ID

22 April 2018

http://europepmc.org/abstract/MED/10606773

1476

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Europe PubMed Central

PubMed publication ID

22 April 2018

http://europepmc.org/abstract/MED/10606773

1

1 reference

Europe PubMed Central

PubMed publication ID

22 April 2018

http://europepmc.org/abstract/MED/10606773

109-128

1 reference

Europe PubMed Central

PubMed publication ID

22 April 2018

http://europepmc.org/abstract/MED/10606773

Nucleoside-phosphorylase deficiency in a child with severely defective T-cell immunity and normal B-cell immunity

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Structure-based design of inhibitors of purine nucleoside phosphorylase. 1. 9-(arylmethyl) derivatives of 9-deazaguanine

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Physiological concentrations of purines and pyrimidines

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Spectral studies on tautomeric forms of inosine

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Properties of two unusual, and fluorescent, substrates of purine-nucleoside phosphorylase: 7-methylguanosine and 7-methylinosine

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72 Purine nucleoside phosphorylase from human erythrocytes

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Fluorescence emission properties of 8-azapurines and their nucleosides, and application to the kinetics of the reverse synthetic reaction of purine nucleoside phosphorylase.

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Fluorescence quenching studies with proteins

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Binding of substrates to human deoxycytidine kinase studied with ligand-dependent quenching of enzyme intrinsic fluorescence.

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Properties of graphical representations of multiple classes of binding sites

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Cooperativity in enzyme function: equilibrium and kinetic aspects

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Time-Domain Fluorescence Spectroscopy Using Time-Correlated Single-Photon Counting

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Use of site-directed mutagenesis to enhance the epitope-shielding effect of covalent modification of proteins with polyethylene glycol

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The crystal structure of Escherichia coli purine nucleoside phosphorylase: a comparison with the human enzyme reveals a conserved topology

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Carbon-13 magnetic resonance spectra of C-nucleosides. 3. la-c Tautomerism in formycin and formycin B and certain pyrazolo[4,3-d]pyrimidines

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Nicotinamide riboside, an unusual, non-typical, substrate of purified purine-nucleoside phosphorylases.

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Crystal structure of the ternary complex of E. coli purine nucleoside phosphorylase with formycin B, a structural analogue of the substrate inosine, and phosphate (Sulphate) at 2.1 A resolution

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Identifiers

10.1016/S0167-4838(99)00225-3

1 reference

Europe PubMed Central

PubMed publication ID

22 April 2018

http://europepmc.org/abstract/MED/10606773

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 April 2018

http://europepmc.org/abstract/MED/10606773

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