(Q52174469)

26 April 2018

title

SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine. (English)

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26 April 2018

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26 April 2018

Doug Hilton

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26 April 2018

Paul J Hertzog

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ORCID Public Data File 2021

Donald Metcalf

object named as

D Metcalf

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26 April 2018

author name string

W S Alexander

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26 April 2018

R Starr

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26 April 2018

J E Fenner

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26 April 2018

C L Scott

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26 April 2018

E Handman

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26 April 2018

N S Sprigg

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26 April 2018

J E Corbin

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26 April 2018

A L Cornish

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26 April 2018

R Darwiche

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26 April 2018

C M Owczarek

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26 April 2018

T W Kay

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26 April 2018

P J Hertzog

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26 April 2018

language of work or name

English

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publication date

1 September 1999

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26 April 2018

published in

Cell

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26 April 2018

volume

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26 April 2018

issue

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26 April 2018

page(s)

597-608

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26 April 2018

Growth hormone preferentially induces the rapid, transient expression of SOCS-3, a novel inhibitor of cytokine receptor signaling

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Multiple defects of immune cell function in mice with disrupted interferon-gamma genes

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Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation

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Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

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Association of serum proteins with cultured Leishmania: a warning note

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Contribution of STAT SH2 groups to specific interferon signaling by the Jak-STAT pathway

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A novel member of the interferon receptor family complements functionality of the murine interferon gamma receptor in human cells

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Intermittent interferonemia and interferon responses in multiple sclerosis

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Twenty proteins containing a C-terminal SOCS box form five structural classes

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Immune response in mice that lack the interferon-gamma receptor

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Targeted disruption of the interferon-gamma receptor 2 gene results in severe immune defects in mice

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Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase

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7 January 2021

Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

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7 January 2021

Aberrant hematopoiesis in mice with inactivation of the gene encoding SOCS-1

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7 January 2021

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7 January 2021

The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction

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7 January 2021

Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon-alpha and -gamma signal transduction pathways

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Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction

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7 January 2021

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7 January 2021

Induction by EGF and interferon-gamma of tyrosine phosphorylated DNA binding proteins in mouse liver nuclei.

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7 January 2021

Transcriptional responses to polypeptide ligands: the JAK-STAT pathway

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7 January 2021

Activation of transcription by IFN-gamma: tyrosine phosphorylation of a 91-kD DNA binding protein

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7 January 2021

Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions

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7 January 2021

The suppressor of cytokine signaling (SOCS) 1 and SOCS3 but not SOCS2 proteins inhibit interferon-mediated antiviral and antiproliferative activities

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7 January 2021

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7 January 2021

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7 January 2021

IFN-gamma action on pancreatic beta cells causes class I MHC upregulation but not diabetes

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7 January 2021

Chronic active hepatitis in transgenic mice expressing interferon-gamma in the liver

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7 January 2021

Naturally occurring dominant negative variants of Stat5.

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7 January 2021

Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway

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7 January 2021

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7 January 2021

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Identifiers

DOI

1 reference

26 April 2018

1 reference

26 April 2018