(Q52030466)

20 April 2018

title

A new method to detect related function among proteins independent of sequence and fold homology. (English)

1 reference

20 April 2018

author name string

Stefan Schmitt

series ordinal

1 reference

20 April 2018

Daniel Kuhn

series ordinal

1 reference

20 April 2018

Gerhard Klebe

series ordinal

1 reference

20 April 2018

language of work or name

English

0 references

publication date

1 October 2002

1 reference

20 April 2018

Journal of Molecular Biology

published in

1 reference

20 April 2018

volume

323

1 reference

20 April 2018

issue

1 reference

20 April 2018

page(s)

387-406

1 reference

20 April 2018

Comparative genomics of the eukaryotes

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Sequencing the entire genomes of free-living organisms: the foundation of pharmacology in the new millennium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Initial sequencing and analysis of the human genome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Detecting protein function and protein-protein interactions from genome sequences

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Proteome Analysis: A Pathway to the Functional Analysis of Proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Proteomics in drug discovery

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

From protein sequence to function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

From protein structure to function.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Protein structure Prediction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

High-throughput crystallography for lead discovery in drug design.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Structural genomics: beyond the human genome project

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Marrying structure and genomics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

From structure to function: approaches and limitations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

A general method applicable to the search for similarities in the amino acid sequence of two proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Protein structure alignment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Improved tools for biological sequence comparison

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Rapid and sensitive sequence comparison with FASTP and FASTA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Protein structure comparison by alignment of distance matrices

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Identification of tertiary structure resemblance in proteins using a maximal common subgraph isomorphism algorithm.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Efficient detection of three-dimensional structural motifs in biological macromolecules by computer vision techniques

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Improved genetic algorithm-based protein structure comparisons: pairwise and multiple superpositions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Protein structure comparisons using a combination of a genetic algorithm, dynamic programming and least-squares minimization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Finding local structural similarities among families of unrelated protein structures: a generic non-linear alignment algorithm

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Identification of structural motifs from protein coordinate data: secondary structure and first-level supersecondary structure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Use of techniques derived from graph theory to compare secondary structure motifs in proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Detection of common three-dimensional substructures in proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Common spatial arrangements of backbone fragments in homologous and non-homologous proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

A geometric algorithm to find small but highly similar 3D substructures in proteins.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

TESS: a geometric hashing algorithm for deriving 3D coordinate templates for searching structural databases. Application to enzyme active sites

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

A graph-theoretic approach to the identification of three-dimensional patterns of amino acid side-chains in protein structures

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Detection of protein three-dimensional side-chain patterns: new examples of convergent evolution.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

A method to search for similar protein local structures at ligand binding sites and its application to adenine recognition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Protein recognition of adenylate: an example of a fuzzy recognition template

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Mapping of protein surface cavities and prediction of enzyme class by a self-organizing neural network.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Three-dimensional, sequence order-independent structural comparison of a serine protease against the crystallographic database reveals active site similarities: potential implications to evolution and to protein folding

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Molecular surface representations by sparse critical points

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

The use of composite crystal-field environments in molecular recognition and the de novo design of protein ligands

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Databases for protein-ligand complexes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

A geometric approach to macromolecule-ligand interactions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

POCKET: a computer graphics method for identifying and displaying protein cavities and their surrounding amino acids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

LIGSITE: automatic and efficient detection of potential small molecule-binding sites in proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Fast prediction and visualization of protein binding pockets with PASS.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Anatomy of protein pockets and cavities: measurement of binding site geometry and implications for ligand design

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Three-dimensional alpha shapes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

The union of balls and its dual shape

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

The automatic search for ligand binding sites in proteins of known three-dimensional structure using only geometric criteria.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

IsoStar: a library of information about nonbonded interactions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Algorithm 457: finding all cliques of an undirected graph

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Upperbound procedures for the identification of similar three-dimensional chemical structures

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

RASMOL: biomolecular graphics for all

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

A 3D sequence-independent representation of the protein data bank

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Selection of representative protein data sets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Enlarged representative set of protein structures

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Mechanisms of catalysis and allosteric regulation of yeast chorismate mutase from crystal structures

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Structural motif of phosphate-binding site common to various protein superfamilies: all-against-all structural comparison of protein-mononucleotide complexes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

X-ray crystal structure of the yeast Kar3 motor domain complexed with Mg.ADP to 2.3 A resolution

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Substrate specificity and assembly of the catalytic center derived from two structures of ligated uridylate kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

The crystal structure of trypanothione reductase from the human pathogen Trypanosoma cruzi at 2.3 A resolution.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Crystal structure of the ternary complex of mouse lung carbonyl reductase at 1.8 A resolution: the structural origin of coenzyme specificity in the short-chain dehydrogenase/reductase family

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Differential binding of S-adenosylmethionine S-adenosylhomocysteine and Sinefungin to the adenine-specific DNA methyltransferase M.TaqI

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

The crystal structure of phenol hydroxylase in complex with FAD and phenol provides evidence for a concerted conformational change in the enzyme and its cofactor during catalysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

The structure of a complex of human 17beta-hydroxysteroid dehydrogenase with estradiol and NADP+ identifies two principal targets for the design of inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Crystal structure of delta(5)-3-ketosteroid isomerase from Pseudomonas testosteroni in complex with equilenin settles the correct hydrogen bonding scheme for transition state stabilization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Crystal structure of calcium-independent subtilisin BPN' with restored thermal stability folded without the prodomain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Crystal structure of the potent natural product inhibitor balanol in complex with the catalytic subunit of cAMP-dependent protein kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

Synthesis, stability, antiviral activity, and protease-bound structures of substrate-mimicking constrained macrocyclic inhibitors of HIV-1 protease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900811-2

10.1016/S0022-2836(02)00811-2

7 January 2021

Identifiers

DOI

1 reference

20 April 2018

1 reference

20 April 2018