(Q51776761)

12 April 2018

http://europepmc.org/abstract/MED/19828817

title

gamma-Secretase: successive tripeptide and tetrapeptide release from the transmembrane domain of beta-carboxyl terminal fragment (English)

1 reference

12 April 2018

http://europepmc.org/abstract/MED/19828817

main subject

transmembrane protein

0 references

author name string

Mako Takami

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665297&resulttype=core&format=json

15 May 2020

Yu Nagashima

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665297&resulttype=core&format=json

15 May 2020

Yoshihisa Sano

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665297&resulttype=core&format=json

15 May 2020

Seiko Ishihara

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665297&resulttype=core&format=json

15 May 2020

Maho Morishima-Kawashima

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665297&resulttype=core&format=json

15 May 2020

Satoru Funamoto

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665297&resulttype=core&format=json

15 May 2020

Yasuo Ihara

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665297&resulttype=core&format=json

15 May 2020

language of work or name

English

0 references

publication date

1 October 2009

1 reference

12 April 2018

http://europepmc.org/abstract/MED/19828817

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665297&resulttype=core&format=json

15 May 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665297&resulttype=core&format=json

15 May 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665297&resulttype=core&format=json

15 May 2020

page(s)

13042-13052

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665297&resulttype=core&format=json

A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity

15 May 2020

cites work

1 reference

12 December 2020

The intramembrane cleavage site of the amyloid precursor protein depends on the length of its transmembrane domain

1 reference

12 December 2020

Generation of C-terminally truncated amyloid-beta peptides is dependent on gamma-secretase activity.

1 reference

12 December 2020

Potential Link between Amyloid β-Protein 42 and C-terminal Fragment γ 49–99 of β-Amyloid Precursor Protein

1 reference

12 December 2020

NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo

1 reference

12 December 2020

Truncated carboxyl-terminal fragments of beta-amyloid precursor protein are processed to amyloid beta-proteins 40 and 42.

1 reference

12 December 2020

Longer forms of amyloid beta protein: implications for the mechanism of intramembrane cleavage by gamma-secretase.

1 reference

12 December 2020

Diverse compounds mimic Alzheimer disease-causing mutations by augmenting Abeta42 production

1 reference

12 December 2020

DAPT-induced intracellular accumulations of longer amyloid beta-proteins: further implications for the mechanism of intramembrane cleavage by gamma-secretase

1 reference

12 December 2020

Equimolar production of amyloid beta-protein and amyloid precursor protein intracellular domain from beta-carboxyl-terminal fragment by gamma-secretase

1 reference

12 December 2020

Electron microscopic structure of purified, active gamma-secretase reveals an aqueous intramembrane chamber and two pores

1 reference

12 December 2020

Abeta46 is processed to Abeta40 and Abeta43, but not to Abeta42, in the low density membrane domains

1 reference

12 December 2020

Phosphoinositides suppress gamma-secretase in both the detergent-soluble and -insoluble states

1 reference

12 December 2020

Cryoelectron microscopy structure of purified gamma-secretase at 12 A resolution

1 reference

12 December 2020

Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

1 reference

12 December 2020

10.1523/JNEUROSCI.2362-09.2009

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665297&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665297&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665297&resulttype=core&format=json