(Q50641076)

17 March 2018

title

Reversal of agonist selectivity by mutations of conserved amino acids in the binding site of nicotinic acetylcholine receptors (English)

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17 March 2018

author name string

Nicole A Horenstein

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17 March 2018

Thomas J McCormack

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17 March 2018

Clare Stokes

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17 March 2018

Ke Ren

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17 March 2018

Roger L Papke

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17 March 2018

language of work or name

English

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publication date

21 December 2006

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17 March 2018

Journal of Biological Chemistry

published in

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17 March 2018

volume

282

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issue

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17 March 2018

page(s)

5899-5909

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17 March 2018

A glia-derived acetylcholine-binding protein that modulates synaptic transmission.

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609202200

Neuronal nicotinic alpha 7 receptor expressed in Xenopus oocytes presents five putative binding sites for methyllycaconitine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609202200

The brain alpha7 nicotinic receptor may be an important therapeutic target for the treatment of Alzheimer's disease: studies with DMXBA (GTS-21).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609202200

Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609202200

An evaluation of neuronal nicotinic acetylcholine receptor activation by quaternary nitrogen compounds indicates that choline is selective for the alpha 7 subtype

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609202200

The structural basis for GTS-21 selectivity between human and rat nicotinic alpha7 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609202200

Initial coupling of binding to gating mediated by conserved residues in the muscle nicotinic receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609202200

Models of the extracellular domain of the nicotinic receptors and of agonist- and Ca2+-binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609202200

Conservation within the RIC-3 gene family. Effectors of mammalian nicotinic acetylcholine receptor expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609202200

Comparative pharmacology of rat and human alpha7 nAChR conducted with net charge analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609202200

Functional significance of aromatic amino acids from three peptide loops of the alpha 7 neuronal nicotinic receptor site investigated by site-directed mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609202200

Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609202200

The characterization of a novel rigid nicotine analog with alpha7-selective nAChR agonist activity and modulation of agonist properties by boron inclusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609202200

Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609202200

21 January 2018

Identifiers

DOI

10.1074/JBC.M609202200

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17 March 2018

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17 March 2018