(Q50335551)

5 March 2018

title

Essential function for the kinase TAK1 in innate and adaptive immune responses (English)

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5 March 2018

Jun Ninomiya-Tsuji

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5 March 2018

Kunihiro Matsumoto

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5 March 2018

author name string

Shintaro Sato

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5 March 2018

Hideki Sanjo

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5 March 2018

Kiyoshi Takeda

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5 March 2018

Masahiro Yamamoto

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5 March 2018

Taro Kawai

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5 March 2018

Osamu Takeuchi

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5 March 2018

Shizuo Akira

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5 March 2018

language of work or name

English

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publication date

25 September 2005

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5 March 2018

published in

Nature Immunology

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5 March 2018

volume

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5 March 2018

issue

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5 March 2018

page(s)

1087-1095

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5 March 2018

Signalling pathways of the TNF superfamily: a double-edged sword

cites work

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7 January 2021

Toll-like receptor signalling

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7 January 2021

Signal transduction by tumor necrosis factor and its relatives

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7 January 2021

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

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7 January 2021

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

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7 January 2021

Missing pieces in the NF-kappaB puzzle

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7 January 2021

The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

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7 January 2021

Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction

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7 January 2021

Mutations in the Drosophila dTAK1 gene reveal a conserved function for MAPKKKs in the control of rel/NF-kappaB-dependent innate immune responses

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7 January 2021

TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway

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7 January 2021

TAK1 mediates an activation signal from toll-like receptor(s) to nuclear factor-kappaB in lipopolysaccharide-stimulated macrophages

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7 January 2021

Elucidation of the c-Jun N-terminal kinase pathway mediated by Estein-Barr virus-encoded latent membrane protein 1.

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7 January 2021

TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction

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7 January 2021

TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway

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7 January 2021

Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling

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7 January 2021

TAB3, a new binding partner of the protein kinase TAK1

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7 January 2021

TAB2 is essential for prevention of apoptosis in fetal liver but not for interleukin-1 signaling

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7 January 2021

Targeted disruption of the Tab1 gene causes embryonic lethality and defects in cardiovascular and lung morphogenesis

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7 January 2021

IL-12p70-dependent Th1 induction by human B cells requires combined activation with CD40 ligand and CpG DNA.

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7 January 2021

Regulation of B-cell signal transduction by adaptor proteins

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7 January 2021

CARMA1, BCL-10 and MALT1 in lymphocyte development and activation.

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7 January 2021

The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes

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7 January 2021

Role of different B-cell subsets in the specific and polyclonal immune response to T-independent antigens type 2

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7 January 2021

Identification of a human NF-kappaB-activating protein, TAB3

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7 January 2021

TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains

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7 January 2021

Unresponsiveness of MyD88-deficient mice to endotoxin

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7 January 2021

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

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7 January 2021

Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO

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7 January 2021

Bcl10 is a positive regulator of antigen receptor-induced activation of NF-kappaB and neural tube closure

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7 January 2021

Requirement for CARMA1 in antigen receptor-induced NF-kappa B activation and lymphocyte proliferation

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7 January 2021

The MAGUK family protein CARD11 is essential for lymphocyte activation

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7 January 2021

Mice lacking the CARD of CARMA1 exhibit defective B lymphocyte development and impaired proliferation of their B and T lymphocytes

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7 January 2021

Regulation of NF-κB-Dependent Lymphocyte Activation and Development by Paracaspase

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7 January 2021

Differential Requirement for Malt1 in T and B Cell Antigen Receptor Signaling

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7 January 2021

Defective development and function of Bcl10-deficient follicular, marginal zone and B1 B cells

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7 January 2021

Gene profiling during neural induction in Xenopus laevis: regulation of BMP signaling by post-transcriptional mechanisms and TAB3, a novel TAK1-binding protein.

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7 January 2021

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

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7 January 2021

Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

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7 January 2021

Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

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7 January 2021

Role of the TAK1-NLK-STAT3 pathway in TGF-beta-mediated mesoderm induction

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7 January 2021

Efficient regulation of gene expression by adenovirus vector-mediated delivery of the CRE recombinase

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7 January 2021

Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines

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7 January 2021

B lymphocyte-specific, Cre-mediated mutagenesis in mice

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7 January 2021

A variety of microbial components induce tolerance to lipopolysaccharide by differentially affecting MyD88-dependent and -independent pathways

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7 January 2021

Synergy and cross-tolerance between toll-like receptor (TLR) 2- and TLR4-mediated signaling pathways

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7 January 2021

Identifiers

DOI

10.1038/NI1255

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5 March 2018

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5 March 2018