(Q48965472)

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The Importance of Having Arc: Expression of the Immediate-Early Gene Arc Is Required for Hippocampus-Dependent Fear Conditioning and Blocked by NMDA Receptor Antagonism

scientific article published on August 3, 2011

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813681%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

The importance of having Arc: expression of the immediate-early gene Arc is required for hippocampus-dependent fear conditioning and blocked by NMDA receptor antagonism (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813681%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

The Importance of Having Arc: Expression of the Immediate-Early Gene Arc Is Required for Hippocampus-Dependent Fear Conditioning and Blocked by NMDA Receptor Antagonism (English)

1 reference

10.1523/JNEUROSCI.2211-11.2011

https://api.crossref.org/works/10.1523/JNEUROSCI.2211-11.2011

8 December 2024

immediate early gene

1 reference

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Jennifer Czerniawski

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813681%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Fredrick Ree

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813681%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Chester Chia

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813681%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Kartik Ramamoorthi

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813681%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Yayoi Kumata

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813681%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Timothy A. Otto

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21813681

8 December 2024

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1 August 2011

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Europe PubMed Central

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9 February 2020

3 August 2011

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21813681

8 December 2024

full work available at URL

https://www.jneurosci.org/content/jneuro/31/31/11200.full.pdf

online access status

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21813681

8 December 2024

https://europepmc.org/articles/PMC6623359

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Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21813681

8 December 2024

https://europepmc.org/articles/PMC6623359?pdf=render

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21813681

8 December 2024

https://doi.org/10.1523/jneurosci.2211-11.2011

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21813681

8 December 2024

https://syndication.highwire.org/content/doi/10.1523/JNEUROSCI.2211-11.2011

1 reference

10.1523/JNEUROSCI.2211-11.2011

https://api.crossref.org/works/10.1523/JNEUROSCI.2211-11.2011

8 December 2024

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813681%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

31

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813681%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

31

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813681%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

11200-11207

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813681%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Environment-specific expression of the immediate-early gene Arc in hippocampal neuronal ensembles.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Double dissociation of function within the hippocampus: a comparison of dorsal, ventral, and complete hippocampal cytotoxic lesions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissociating context and space within the hippocampus: effects of complete, dorsal, and ventral excitotoxic hippocampal lesions on conditioned freezing and spatial learning.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of activity-dependent arc protein expression in the rat hippocampus impairs the maintenance of long-term potentiation and the consolidation of long-term memory.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective targeting of newly synthesized Arc mRNA to active synapses requires NMDA receptor activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experience-dependent gene expression in the rat hippocampus after spatial learning: a comparison of the immediate-early genes Arc, c-fos, and zif268.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ventral hippocampus and fear conditioning in rats. Different anterograde amnesias of fear after tetrodotoxin inactivation and infusion of the GABA(A) agonist muscimol

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insights into immediate-early gene function in hippocampal memory consolidation using antisense oligonucleotide and fluorescent imaging approaches

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acquisition of a novel behavior induces higher levels of Arc mRNA than does overtrained performance

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Learning-induced arg 3.1/arc mRNA expression in the mouse brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hippocampus and Pavlovian fear conditioning in rats: muscimol infusions into the ventral, but not dorsal, hippocampus impair the acquisition of conditional freezing to an auditory conditional stimulus

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMDA receptors, place cells and hippocampal spatial memory

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trace fear conditioning depends on NMDA receptor activation and protein synthesis within the dorsal hippocampus of mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Time-dependent involvement of the dorsal hippocampus in trace fear conditioning in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modality-specific retrograde amnesia of fear

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dorsal hippocampus NMDA receptors differentially mediate trace and contextual fear conditioning

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Memory-influencing intra-basolateral amygdala drug infusions modulate expression of Arc protein in the hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fornix lesions decouple the induction of hippocampal arc transcription from behavior but not plasticity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amygdala regulation of immediate-early gene expression in the hippocampus induced by contextual fear conditioning.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spatial exploration induces ARC, a plasticity-related immediate-early gene, only in calcium/calmodulin-dependent protein kinase II-positive principal excitatory and inhibitory neurons of the rat forebrain

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arc/Arg3.1 is essential for the consolidation of synaptic plasticity and memories.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arc/Arg3.1 interacts with the endocytic machinery to regulate AMPA receptor trafficking

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of the immediate-early gene arc/arg3.1 reduces AMPA receptor-mediated synaptic transmission

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential contributions of dorsal vs. ventral hippocampus to auditory trace fear conditioning

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sustained Arc/Arg3.1 synthesis controls long-term potentiation consolidation through regulation of local actin polymerization in the dentate gyrus in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Networks of neurons, networks of genes: an integrated view of memory consolidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid translation of Arc/Arg3.1 selectively mediates mGluR-dependent LTD through persistent increases in AMPAR endocytosis rate

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissociating space and trace in dorsal and ventral hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The self-tuning neuron: synaptic scaling of excitatory synapses

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The activity-regulated cytoskeletal-associated protein (Arc/Arg3.1) is required for memory consolidation of pavlovian fear conditioning in the lateral amygdala

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Arc of synaptic memory

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Time-dependent expression of Arc and zif268 after acquisition of fear conditioning

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New views of Arc, a master regulator of synaptic plasticity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Somatodendritic expression of an immediate early gene is regulated by synaptic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arc, a growth factor and activity-regulated gene, encodes a novel cytoskeleton-associated protein that is enriched in neuronal dendrites

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic activation causes the mRNA for the IEG Arc to localize selectively near activated postsynaptic sites on dendrites

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional differentiation in the hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hippocampectomy disrupts auditory trace fear conditioning and contextual fear conditioning in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21813681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insights into immediate-early gene function in hippocampal memory consolidation using antisense oligonucleotide and fluorescent imaging approaches

9

1 reference

10.1523/JNEUROSCI.2211-11.2011

https://api.crossref.org/works/10.1523/JNEUROSCI.2211-11.2011

8 December 2024

Identifiers

10.1523/JNEUROSCI.2211-11.2011

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813681%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813681%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813681%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

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