(Q48630214)

English

Phosphatidylinositol 3′-Kinase-independent p70 S6 Kinase Activation by Fibroblast Growth Factor Receptor-1 Is Important for Proliferation but Not Differentiation of Endothelial Cells

scientific article published on September 12, 1997

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/9287347

Phosphatidylinositol 3'-kinase-independent p70 S6 kinase activation by fibroblast growth factor receptor-1 is important for proliferation but not differentiation of endothelial cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/9287347

Phosphatidylinositol 3′-Kinase-independent p70 S6 Kinase Activation by Fibroblast Growth Factor Receptor-1 Is Important for Proliferation but Not Differentiation of Endothelial Cells (English)

1 reference

10.1074/JBC.272.37.23347

https://api.crossref.org/works/10.1074/JBC.272.37.23347

14 November 2024

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receptor tyrosine kinase

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9287347

14 November 2024

Michael Wakelam

4

object named as

M. J. Wakelam

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9287347

14 November 2024

author name string

S. Kanda

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9287347

14 November 2024

M. N. Hodgkin

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9287347

14 November 2024

R. J. Woodfield

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9287347

14 November 2024

G. Thomas

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9287347

14 November 2024

L. Claesson-Welsh

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9287347

14 November 2024

language of work or name

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publication date

1 September 1997

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Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/9287347

12 September 1997

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9287347

14 November 2024

number of pages

7

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full work available at URL

http://www.jbc.org/content/272/37/23347.full.pdf

online access status

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9287347

14 November 2024

https://api.elsevier.com/content/article/PII:S0021925819655869?httpAccept=text/xml

1 reference

10.1074/JBC.272.37.23347

https://api.crossref.org/works/10.1074/JBC.272.37.23347

14 November 2024

https://api.elsevier.com/content/article/PII:S0021925819655869?httpAccept=text/plain

1 reference

10.1074/JBC.272.37.23347

https://api.crossref.org/works/10.1074/JBC.272.37.23347

14 November 2024

https://syndication.highwire.org/content/doi/10.1074/jbc.272.37.23347

1 reference

10.1074/JBC.272.37.23347

https://api.crossref.org/works/10.1074/JBC.272.37.23347

14 November 2024

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/9287347

272

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/9287347

37

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/9287347

23347-23353

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/9287347

Identification and characterization of a mitogen-activated S6 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

p70 S6 kinase: an enigma with variations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

A single gene encodes two isoforms of the p70 S6 kinase: activation upon mitogenic stimulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

Cloning and expression of two human p70 S6 kinase polypeptides differing only at their amino termini

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

Activation of p70s6k is associated with phosphorylation of four clustered sites displaying Ser/Thr-Pro motifs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

MAP2 kinase and 70K S6 kinase lie on distinct signalling pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

Activation of p70/p85 S6 kinase by a pathway independent of p21ras

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

The 70 kDa S6 kinase: regulation of a kinase with multiple roles in mitogenic signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate p70s6k by inducing dephosphorylation of the same subset of sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

A mammalian protein targeted by G1-arresting rapamycin-receptor complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

Control of p70 s6 kinase by kinase activity of FRAP in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

Diverse receptors for fibroblast growth factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

Shc and a novel 89-kDa component couple to the Grb2-Sos complex in fibroblast growth factor-2-stimulated cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

cDNA cloning and expression of a human FGF receptor which binds acidic and basic FGF.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

Wortmannin and its structural analogue demethoxyviridin inhibit stimulated phospholipase A2 activity in Swiss 3T3 cells. Wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

The Rapamycin and FKBP12 Target (RAFT) Displays Phosphatidylinositol 4-Kinase Activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

When is a lipid kinase not a lipid kinase? When it is a protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

The principal rapamycin-sensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

Multiple independent inputs are required for activation of the p70 S6 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

Phosphatidylinositol 3-OH kinase activity is not required for activation of mitogen-activated protein kinase by cytokines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

Phosphatidylinositol 3-kinase is an early intermediate in the G beta gamma-mediated mitogen-activated protein kinase signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

Inositol trisphosphate and calcium signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

Point mutation of an FGF receptor abolishes phosphatidylinositol turnover and Ca2+ flux but not mitogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

Point mutation in FGF receptor eliminates phosphatidylinositol hydrolysis without affecting mitogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

p70s6k function is essential for G1 progression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.37.23347

21 January 2018

p70 S6 kinase: an enigma with variations

2

1 reference

10.1074/JBC.272.37.23347

https://api.crossref.org/works/10.1074/JBC.272.37.23347

14 November 2024

TOR kinase domains are required for two distinct functions, only one of which is inhibited by rapamycin

16

1 reference

10.1074/JBC.272.37.23347

https://api.crossref.org/works/10.1074/JBC.272.37.23347

14 November 2024

The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain.

19

1 reference

10.1074/JBC.272.37.23347

https://api.crossref.org/works/10.1074/JBC.272.37.23347

14 November 2024

Nuclear localization of p85s6k: functional requirement for entry into S phase.

21

1 reference

10.1074/JBC.272.37.23347

https://api.crossref.org/works/10.1074/JBC.272.37.23347

14 November 2024

Molecular mechanisms of angiogenesis: fibroblast growth factor signal transduction.

22

1 reference

10.1074/JBC.272.37.23347

https://api.crossref.org/works/10.1074/JBC.272.37.23347

14 November 2024

EGF induces biphasic S6 kinase activation: late phase is protein kinase C-dependent and contributes to mitogenicity

32

1 reference

10.1074/JBC.272.37.23347

https://api.crossref.org/works/10.1074/JBC.272.37.23347

14 November 2024

FKBP12-rapamycin target TOR2 is a vacuolar protein with an associated phosphatidylinositol-4 kinase activity.

35

1 reference

10.1074/JBC.272.37.23347

https://api.crossref.org/works/10.1074/JBC.272.37.23347

14 November 2024

Normal Activation of P70 S6 Kinase by Insulin in Cells Overexpressing Dominant Negative 85-kDa Subunit of Phosphoinositide 3-Kinase

43

1 reference

10.1074/JBC.272.37.23347

https://api.crossref.org/works/10.1074/JBC.272.37.23347

14 November 2024

Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002.

44

1 reference

10.1074/JBC.272.37.23347

https://api.crossref.org/works/10.1074/JBC.272.37.23347

14 November 2024

Identifiers

10.1074/JBC.272.37.23347

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/9287347

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/9287347

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