(Q48626694)

13 February 2018

title

Localization of cocaine analog [125I]RTI 82 irreversible binding to transmembrane domain 6 of the dopamine transporter (English)

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13 February 2018

main subject

transmembrane protein

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13 February 2018

Romain A Duval

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13 February 2018

author name string

Roxanne A Vaughan

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13 February 2018

M Laura Parnas

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13 February 2018

Steven Adkins

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13 February 2018

James D Foster

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13 February 2018

John R Lever

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13 February 2018

Santosh S Kulkarni

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13 February 2018

Amy Hauck-Newman

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13 February 2018

language of work or name

English

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publication date

25 January 2007

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13 February 2018

Journal of Biological Chemistry

published in

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13 February 2018

volume

282

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13 February 2018

issue

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13 February 2018

page(s)

8915-8925

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13 February 2018

Dopamine transporters and neuronal injury

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Synthesis, biodistribution, and primate imaging of fluorine-18 labeled 2beta-carbo-1'-fluoro-2-propoxy-3beta-(4-chlorophenyl)tr opanes. Ligands for the imaging of dopamine transporters by positron emission tomography

21 January 2018

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Synthesis and biological evaluation of a new set of pyrazolo[1,5-c]quinazoline-2-carboxylates as novel excitatory amino acid antagonists

21 January 2018

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Probes for the cocaine receptor. Potentially irreversible ligands for the dopamine transporter

21 January 2018

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Dopamine transporter ligand binding domains. Structural and functional properties revealed by limited proteolysis

21 January 2018

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Transport-dependent accessibility of a cytoplasmic loop cysteine in the human dopamine transporter

21 January 2018

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Uptake inhibitors but not substrates induce protease resistance in extracellular loop two of the dopamine transporter

21 January 2018

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The functional domains of dopamine transporter for cocaine analog, CFT binding

21 January 2018

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The role of conserved tryptophan and acidic residues in the human dopamine transporter as characterized by site-directed mutagenesis

21 January 2018

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Identification of intracellular residues in the dopamine transporter critical for regulation of transporter conformation and cocaine binding.

21 January 2018

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Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants

21 January 2018

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Zn(2+) site engineering at the oligomeric interface of the dopamine transporter.

21 January 2018

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Cocaine alters the accessibility of endogenous cysteines in putative extracellular and intracellular loops of the human dopamine transporter.

21 January 2018

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A pincer-like configuration of TM2 in the human dopamine transporter is responsible for indirect effects on cocaine binding.

21 January 2018

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Aspartate 345 of the dopamine transporter is critical for conformational changes in substrate translocation and cocaine binding

21 January 2018

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Mutation of Trp84 and Asp313 of the dopamine transporter reveals similar mode of binding interaction for GBR12909 and benztropine as opposed to cocaine.

21 January 2018

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Cocaine receptor: biochemical characterization and structure-activity relationships of cocaine analogues at the dopamine transporter

21 January 2018

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Novel tropane-based irreversible ligands for the dopamine transporter

21 January 2018

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Radioiodinated azide and isothiocyanate derivatives of cocaine for irreversible labeling of dopamine transporters: synthesis and covalent binding studies

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M610633200

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13 February 2018

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13 February 2018