(Q48640592)

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Anxiolytic effects of 3α-hydroxy-5α[β]-pregnan-20-one: endogenous metabolites of progesterone that are active at the GABAA receptor

scientific article published on October 4, 1991

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Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/1686744

Anxiolytic effects of 3α-hydroxy-5α[β]-pregnan-20-one: endogenous metabolites of progesterone that are active at the GABAA receptor (English)

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10.1016/0006-8993(91)90761-J

https://api.crossref.org/works/10.1016/0006-8993(91)90761-J

29 October 2022

Anxiolytic effects of 3 alpha-hydroxy-5 alpha[beta]-pregnan-20-one: endogenous metabolites of progesterone that are active at the GABAA receptor (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1686744

29 October 2022

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D. Bitran

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1686744

29 October 2022

R. J. Hilvers

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1686744

29 October 2022

C. K. Kellogg

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1686744

29 October 2022

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1 October 1991

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PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/1686744

4 October 1991

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National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1686744

29 October 2022

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https://api.elsevier.com/content/article/PII:000689939190761J?httpAccept=text/xml

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10.1016/0006-8993(91)90761-J

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29 October 2022

https://api.elsevier.com/content/article/PII:000689939190761J?httpAccept=text/plain

1 reference

10.1016/0006-8993(91)90761-J

https://api.crossref.org/works/10.1016/0006-8993(91)90761-J

29 October 2022

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/1686744

561

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Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/1686744

1

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Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/1686744

157-161

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Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/1686744

Anticonvulsant profile of the progesterone metabolite 5 alpha-pregnan-3 alpha-ol-20-one

1

1 reference

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Anticonvulsant steroids and the GABA/benzodiazepine receptor-chloride ionophore complex

2

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Ovarian endocrine status modulates the anxiolytic potency of diazepam and the efficacy of !g-aminobutyric acid-benzodiazepine receptor-mediated chloride ion transport

3

1 reference

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Effects of progesterone on [35S] t-butylbicyclophosphorothionate binding in some forebrain areas of the female rat and its correlation to aggressive behavior.

4

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Anxiolytic activity of an endogenous adrenal steroid

5

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GABA-dependent modulation of the Cl- ionophore by steroids in rat brain.

7

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Analgesic effects of the progesterone metabolite, 3 alpha-hydroxy-5 alpha-pregnan-20-one, and possible modes of action in mice

8

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Enhancement of [3H]muscimol binding to brain synaptic membranes by progesterone and related pregnanes

11

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Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor

12

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Gonadal Steroid Action on the Brain: Neurochemistry and Neuropharmacology

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Sleep induction by an adrenal steroid in the rat.

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Steroid hormone metabolites potentiate GABA receptor-mediated chloride ion flux with nanomolar potency

16

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The anaesthetic potency of 3 alpha-hydroxy-5 alpha-pregnan-20-one and 3 alpha-hydroxy-5 beta-pregnan-20-one determined with an intravenous EEG-threshold method in male rats.

17

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Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

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Modulation of the GABAA receptor by depressant barbiturates and pregnane steroids

20

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Neurosteroids act on recombinant human GABAA receptors

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Radioimmunoassay of 3 alpha-hydroxy-5 alpha-pregnan-20-one in rat and human plasma

22

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Synthesis, metabolism, and pharmacological activity of 3 alpha-hydroxy steroids which potentiate GABA-receptor-mediated chloride ion uptake in rat cerebral cortical synaptoneurosomes

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Anxiolytic effects of progesterone are sexually dimorphic

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Effect of ovarian hormones on conflict behavior.

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Rapid membrane effects of steroid hormones: an emerging concept in neuroendocrinology

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Modulation of the GABAA receptor complex by steroids in slices of rat cuneate nucleus

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29 October 2022

Identifiers

10.1016/0006-8993(91)90761-J

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/1686744

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/1686744

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