(Q48259051)

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β-adrenergic stimulation augments transmural dispersion of repolarization via modulation of delayed rectifier currents IKs and IKr in the human ventricle

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Europe PubMed Central

PMC publication ID

10 February 2018

http://europepmc.org/abstract/PMC/5698468

β-adrenergic stimulation augments transmural dispersion of repolarization via modulation of delayed rectifier currents IKs and IKr in the human ventricle (English)

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Europe PubMed Central

PMC publication ID

10 February 2018

http://europepmc.org/abstract/PMC/5698468

Natalia Trayanova

6

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29162896%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

7

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29162896%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

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C Kang

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29162896%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

A Badiceanu

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29162896%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

J A Brennan

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29162896%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

C Gloschat

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29162896%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Y Qiao

5

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Europe PubMed Central

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10 June 2020

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21 November 2017

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Europe PubMed Central

PMC publication ID

10 February 2018

http://europepmc.org/abstract/PMC/5698468

Scientific Reports

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29162896%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

7

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29162896%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29162896%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

15922

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29162896%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

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Creative Commons Attribution 4.0 International

21 November 2017

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April 2022 Public Data File from Crossref

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0 references

Molecular Pathophysiology of Congenital Long QT Syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

Human Organotypic Cultured Cardiac Slices: New Platform For High Throughput Preclinical Human Trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

Improving cardiomyocyte model fidelity and utility via dynamic electrophysiology protocols and optimization algorithms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

Reduced response to IKr blockade and altered hERG1a/1b stoichiometry in human heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

Arrhythmogenic remodeling of β2 versus β1 adrenergic signaling in the human failing heart.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

Sodium channels in the Cx43 gap junction perinexus may constitute a cardiac ephapse: an experimental and modeling study

1 reference

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22 May 2018

Adverse remodeling of the electrophysiological response to ischemia-reperfusion in human heart failure is associated with remodeling of metabolic gene expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

Prediction of Thorough QT study results using action potential simulations based on ion channel screens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

Beta-adrenergic stimulation reverses the I Kr-I Ks dominant pattern during cardiac action potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

Processing and analysis of cardiac optical mapping data obtained with potentiometric dyes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

Simulation of the undiseased human cardiac ventricular action potential: model formulation and experimental validation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

Transmural heterogeneity and remodeling of ventricular excitation-contraction coupling in human heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

Local control of β-adrenergic stimulation: Effects on ventricular myocyte electrophysiology and Ca2+-transient

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

Sequential dissection of multiple ionic currents in single cardiac myocytes under action potential-clamp

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

The cardiac I Ks channel, complex indeed

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

Effects of β‐adrenoceptor stimulation on delayed rectifier K+ currents in canine ventricular cardiomyocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

So Little Source, So Much Sink: Requirements for Afterdepolarizations to Propagate in Tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

Transmural dispersion of repolarization in failing and nonfailing human ventricle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

Prevalence of the congenital long-QT syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

A novel computational model of the human ventricular action potential and Ca transient

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

The structure and function of G-protein-coupled receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

Blockade of the I(Ks) potassium channel: an overlooked cardiovascular liability in drug safety screening?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

Mechanisms of beta-adrenergic modulation of I(Ks) in the guinea-pig ventricle: insights from experimental and model-based analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

Ionic, molecular, and cellular bases of QT-interval prolongation and torsade de pointes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

Is heart size a factor in ventricular fibrillation? Or how close are rabbit and human hearts?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

Risk stratification in the long-QT syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

Pharmacological block of the slow component of the outward delayed rectifier current (I(Ks)) fails to lengthen rabbit ventricular muscle QT(c) and action potential duration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

Influence of the genotype on the clinical course of the long-QT syndrome. International Long-QT Syndrome Registry Research Group.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

Delayed rectifier channels in human ventricular myocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

Catecholamines modulate the delayed rectifying potassium current (IK) in guinea pig ventricular myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

Two components of cardiac delayed rectifier K+ current. Differential sensitivity to block by class III antiarrhythmic agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

Mechanism of receptor-mediated modulation of the delayed outward potassium current in guinea-pig ventricular myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

Characterization of two distinct depolarization-activated K+ currents in isolated adult rat ventricular myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

22 May 2018

Differential roles of two delayed rectifier potassium currents in regulation of ventricular action potential duration and arrhythmia susceptibility.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

14 August 2018

Feasibility of a semi-automated method for cardiac conduction velocity analysis of high-resolution activation maps.

1 reference

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14 August 2018

Restricting excessive cardiac action potential and QT prolongation: a vital role for IKs in human ventricular muscle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

14 August 2018

A model for human ventricular tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

14 August 2018

beta3-Adrenergic regulation of an ion channel in the heart-inhibition of the slow delayed rectifier potassium current I(Ks) in guinea pig ventricular myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

14 August 2018

Effects of the I(Kr)-blocking agent dofetilide and of the I(Ks)-blocking agent chromanol 293b on regional disparity of left ventricular repolarization in the intact canine heart

1 reference

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14 August 2018

Density and kinetics of I(Kr) and I(Ks) in guinea pig and rabbit ventricular myocytes explain different efficacy of I(Ks) blockade at high heart rate in guinea pig and rabbit: implications for arrhythmogenesis in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698468

14 August 2018

Effects of the chromanol 293B, a selective blocker of the slow, component of the delayed rectifier K+ current, on repolarization in human and guinea pig ventricular myocytes

1 reference

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14 August 2018

Alterations of K+ currents in isolated human ventricular myocytes from patients with terminal heart failure

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-16218-3

21 January 2018

IKs, a slow and intriguing cardiac K+ channel and its associated long QT diseases

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-16218-3

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of the delayed rectifier component IKs in dog ventricular muscle and Purkinje fibre repolarization

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-16218-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence for two components of delayed rectifier K+ current in human ventricular myocytes

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-16218-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Isoproterenol antagonizes prolongation of refractory period by the class III antiarrhythmic agent E-4031 in guinea pig myocytes. Mechanism of action

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-16218-3

7 January 2021

based on heuristic

inferred from DOI database lookup

The expression, phosphorylation, and localization of connexin 43 and gap-junctional intercellular communication during the establishment of a synchronized contraction of cultured neonatal rat cardiac myocytes

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-16218-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Repolarization reserve determines drug responses in human pluripotent stem cell derived cardiomyocytes

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-16218-3

7 January 2021

based on heuristic

inferred from DOI database lookup

In vivo mechanisms precipitating torsades de pointes in a canine model of drug-induced long-QT1 syndrome

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-16218-3

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based on heuristic

inferred from DOI database lookup

Heterogeneous transmural distribution of beta-adrenergic receptor subtypes in failing human hearts

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-16218-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Transient outward and delayed rectifier currents in canine atrium: properties and role of isolation methods

1 reference

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inferred from PubMed ID database lookup

Identifiers

10.1038/S41598-017-16218-3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29162896%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

release_g7vuetwux5dg3d4jwov73jpooq

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29162896%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29162896%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

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