(Q47713194)

5 February 2018

title

Somatic hypermutation in the heavy chain locus correlates with transcription (English)

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5 February 2018

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5 February 2018

Klaus Rajewsky

series ordinal

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5 February 2018

author name string

Y Fukita

series ordinal

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5 February 2018

language of work or name

English

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publication date

1 July 1998

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5 February 2018

published in

Immunity

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5 February 2018

volume

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5 February 2018

issue

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5 February 2018

page(s)

105-114

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5 February 2018

Coordination of immunoglobulin DJH transcription and D-to-JH rearrangement by promoter-enhancer approximation

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7 January 2021

Nonsense mutations inhibit RNA splicing in a cell-free system: recognition of mutant codon is independent of protein synthesis

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7 January 2021

Maturation of the immune response in germinal centers

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7 January 2021

Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region

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7 January 2021

Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes

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7 January 2021

Nonsense codons can reduce the abundance of nuclear mRNA without affecting the abundance of pre-mRNA or the half-life of cytoplasmic mRNA.

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7 January 2021

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Surface antigen expression and immunoglobulin gene rearrangement during mouse pre-B cell development

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Analysis of individual immunoglobulin lambda light chain genes amplified from single cells is inconsistent with variable region gene conversion in germinal-center B cell somatic mutation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Flow cytometric analysis of cell proliferation dynamics in the B cell compartment of the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Clusters of point mutations are found exclusively around rearranged antibody variable genes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Somatic mutation of immunoglobulin lambda chains: a segment of the major intron hypermutates as much as the complementarity-determining regions

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Cells strongly expressing Ig(kappa) transgenes show clonal recruitment of hypermutation: a role for both MAR and the enhancers.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Efficient transcription of a protein-coding gene from the RNA polymerase I promoter in transfected cells

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7 January 2021

T cell-activating properties of an anti-Thy-1 monoclonal antibody. Possible analogy to OKT3/Leu-4

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Intraclonal generation of antibody mutants in germinal centres

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Hypermutation of immunoglobulin genes in memory B cells of DNA repair-deficient mice

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7 January 2021

Fidelity of DNA polymerases in DNA amplification

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Antibody diversity: somatic hypermutation of rearranged VH genes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

A survey of protein-DNA interaction sites within the murine immunoglobulin heavy chain locus reveals a particularly complex pattern around the DQ52 element

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

A second promoter and enhancer element within the immunoglobulin heavy chain locus.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

A 140-base-pair repetitive sequence element in the mouse rRNA gene spacer enhances transcription by RNA polymerase I in a cell-free system

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Generation and analysis of interleukin-4 deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

A foreign beta-globin gene in transgenic mice: integration at abnormal chromosomal positions and expression in inappropriate tissues

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Simplified mammalian DNA isolation procedure

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Xenogeneic Monoclonal Antibodies to Mouse Lymphoid Differentiation Antigens*

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Low cytoplasmic mRNA levels of immunoglobulin kappa light chain genes containing nonsense codons correlate with inefficient splicing.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

High gradient magnetic cell separation with MACS

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Somatic hypermutation of an immunoglobulin transgene in kappa transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

The general transcription factors of RNA polymerase II

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Nonsense-mediated mRNA decay in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Somatic hypermutation of immunoglobulin genes is linked to transcription initiation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

The 5' hypermutation boundary of kappa chains is independent of local and neighbouring sequences and related to the distance from the initiation of transcription.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Clonal selection and learning in the antibody system

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

rRNA synthesis in the nucleolus

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Analysis of the repertoire of anti-(4-hydroxy-3-nitro-phenyl)acetyl (NP) antibodies in C 57 BL/6 mice by cell fusion. II. Characterization of idiotopes by monoclonal anti-idiotope antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Mouse anti-mouse IgD monoclonal antibodies generated in IgD-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Mapping the upstream boundary of somatic mutations in rearranged immunoglobulin transgenes and endogenous genes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Peanut lectin binding properties of germinal centres of mouse lymphoid tissue.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Somatic hypermutation in 5' flanking regions of heavy chain antibody variable regions

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Somatic hypermutation of immunoglobulin kappa may depend on sequences 3' of C kappa and occurs on passenger transgenes.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Transcription of herpes simplex virus tk sequences under the control of wild-type and mutant human RNA polymerase I promoters

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

B cell development under the condition of allelic inclusion.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Mac-1: a macrophage differentiation antigen identified by monoclonal antibody

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Targeted insertion of a variable region gene into the immunoglobulin heavy chain locus

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Immunoglobulin heavy chain germ-line JH-C mu transcription in human precursor B lymphocytes initiates in a unique region upstream of DQ52.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Fidelity of DNA synthesis by the Thermus aquaticus DNA polymerase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

The transcriptional promoter regulates hypermutation of the antibody heavy chain locus

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Diversity and joining segments of mouse immunoglobulin heavy chain genes are closely linked and in the same orientation: implications for the joining mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Targeting of non-Ig sequences in place of the V segment by somatic hypermutation.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Recycling of the general transcription factors during RNA polymerase II transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Advances in RNA polymerase II transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

Localization of pre-mRNA splicing in mammalian nuclei

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980592-0

7 January 2021

10.1016/S1074-7613(00)80592-0

Identifiers

DOI

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5 February 2018

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5 February 2018