(Q47621572)

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Induction of Systemic Autoimmunity by a Xenobiotic Requires Endosomal TLR Trafficking and Signaling from the Late Endosome and Endolysosome but Not Type I IFN.

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7 April 2020

Induction of Systemic Autoimmunity by a Xenobiotic Requires Endosomal TLR Trafficking and Signaling from the Late Endosome and Endolysosome but Not Type I IFN (English)

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7 April 2020

toll-like receptor

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Gabriela M Escalante

2

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7 April 2020

Joseph M Christy

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7 April 2020

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7 April 2020

Rosana Gonzalez-Quintial

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Rosana Gonzalez-Quintial

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7 April 2020

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K Michael Pollard

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7 April 2020

Hua Huang

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7 April 2020

Katarina M Haraldsson

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7 April 2020

Per Hultman

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7 April 2020

Jessica M Mayeux

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7 April 2020

Roberto Baccala

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7 April 2020

Argyrios N Theofilopoulos

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7 April 2020

Dwight H Kono

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7 April 2020

Bruce Beutler

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7 April 2020

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20 October 2017

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7 April 2020

Journal of Immunology

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7 April 2020

199

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7 April 2020

11

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7 April 2020

3739-3747

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7 April 2020

From the Cover: Interplay Between IFN-γ and IL-6 Impacts the Inflammatory Response and Expression of Interferon-Regulated Genes in Environmental-Induced Autoimmunity.

1 reference

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29 September 2018

Nucleic acid-sensing TLRs: trafficking and regulation.

1 reference

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29 September 2018

New insights into the immunopathogenesis of systemic lupus erythematosus.

1 reference

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29 September 2018

Nucleic acid-sensing TLRs and autoimmunity: novel insights from structural and cell biology

1 reference

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29 September 2018

Animal Models of Interferon Signature Positive Lupus

1 reference

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29 September 2018

Ethylmercury and Hg2+ induce the formation of neutrophil extracellular traps (NETs) by human neutrophil granulocytes.

1 reference

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29 September 2018

Slc15a4 function is required for intact class switch recombination to IgG2c in response to TLR9 stimulation

1 reference

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29 September 2018

The histidine transporter SLC15A4 coordinates mTOR-dependent inflammatory responses and pathogenic antibody production

1 reference

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29 September 2018

Cathepsin B regulates the appearance and severity of mercury-induced inflammation and autoimmunity

1 reference

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29 September 2018

Early, transient depletion of plasmacytoid dendritic cells ameliorates autoimmunity in a lupus model

1 reference

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29 September 2018

Genetic evidence for the role of plasmacytoid dendritic cells in systemic lupus erythematosus

1 reference

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29 September 2018

Novel biomarkers of mercury-induced autoimmune dysfunction: a cross-sectional study in Amazonian Brazil

1 reference

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29 September 2018

Assessment of the translational value of mouse lupus models using clinically relevant biomarkers

1 reference

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29 September 2018

TLRs and interferons: a central paradigm in autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698107

29 September 2018

Processing of human toll-like receptor 7 by furin-like proprotein convertases is required for its accumulation and activity in endosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698107

29 September 2018

Lysosome-related organelles: unusual compartments become mainstream

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698107

29 September 2018

Role of nucleic acid-sensing TLRs in diverse autoantibody specificities and anti-nuclear antibody-producing B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698107

29 September 2018

UNC93B1 mediates differential trafficking of endosomal TLRs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698107

29 September 2018

Essential requirement for IRF8 and SLC15A4 implicates plasmacytoid dendritic cells in the pathogenesis of lupus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698107

29 September 2018

The interferon signature in autoimmune diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698107

29 September 2018

Noncanonical autophagy is required for type I interferon secretion in response to DNA-immune complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698107

29 September 2018

Presentation of phagocytosed antigens by MHC class I and II.

1 reference

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29 September 2018

Slc15a4, a gene required for pDC sensing of TLR ligands, is required to control persistent viral infection

1 reference

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29 September 2018

Cleavage of Toll-like receptor 3 by cathepsins B and H is essential for signaling

1 reference

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29 September 2018

Definition of IFN-γ-related pathways critical for chemically-induced systemic autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698107

29 September 2018

Adaptor protein-3 in dendritic cells facilitates phagosomal toll-like receptor signaling and antigen presentation to CD4(+) T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698107

29 September 2018

Role of type I interferons in the activation of autoreactive B cells

1 reference

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29 September 2018

The Lbw2 locus promotes autoimmune hemolytic anemia

1 reference

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29 September 2018

Intracellular nucleic acid sensors and autoimmunity

1 reference

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29 September 2018

The type I interferon system in the development of lupus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698107

29 September 2018

Plasmacytoid Dendritic Cells: Recent Progress and Open Questions

1 reference

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29 September 2018

Dendritic cells in lupus are not required for activation of T and B cells but promote their expansion, resulting in tissue damage

1 reference

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29 September 2018

Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698107

29 September 2018

Interferon-α accelerates murine systemic lupus erythematosus in a T cell-dependent manner

1 reference

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29 September 2018

Bifurcation of Toll-Like Receptor 9 Signaling by Adaptor Protein 3

1 reference

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29 September 2018

The interferon-α signature of systemic lupus erythematosus

1 reference

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29 September 2018

The nuclear factor-kappaB-interleukin-6 signalling pathway mediating vascular inflammation.

1 reference

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29 September 2018

Mercury exposure, serum antinuclear/antinucleolar antibodies, and serum cytokine levels in mining populations in Amazonian Brazil: a cross-sectional study

1 reference

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29 September 2018

Sensors of the innate immune system: their link to rheumatic diseases

1 reference

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29 September 2018

Mercury-induced membranous nephropathy: clinical and pathological features

1 reference

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29 September 2018

Sensors of the innate immune system: their mode of action

1 reference

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29 September 2018

Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus

1 reference

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29 September 2018

AP-3-dependent trafficking and disease: the first decade

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29 September 2018

Gold- and silver-induced murine autoimmunity--requirement for cytokines and CD28 in murine heavy metal-induced autoimmunity

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29 September 2018

The roles of the classical and alternative nuclear factor-kappaB pathways: potential implications for autoimmunity and rheumatoid arthritis

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29 September 2018

Interferon alpha-induced lupus: proof of principle

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29 September 2018

Systemic IFN-alpha drives kidney nephritis in B6.Sle123 mice

1 reference

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29 September 2018

Cathepsins are required for Toll-like receptor 9 responses

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29 September 2018

Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis

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29 September 2018

Signaling to NF-kappaB by Toll-like receptors

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29 September 2018

Deficiency of the type I interferon receptor protects mice from experimental lupus

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29 September 2018

Reduced expression of decay-accelerating factor 1 on CD4+ T cells in murine systemic autoimmune disease

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29 September 2018

TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity

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29 September 2018

Genetics of SLE in mice

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29 September 2018

Efficient T cell activation via a Toll-Interleukin 1 Receptor-independent pathway

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29 September 2018

The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9

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29 September 2018

Interferon-beta: a therapeutic for autoimmune lupus in MRL-Faslpr mice

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29 September 2018

The yin and yang of type I interferon activity in bacterial infection

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29 September 2018

IRF-7 is the master regulator of type-I interferon-dependent immune responses

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29 September 2018

Type I interferons (alpha/beta) in immunity and autoimmunity

1 reference

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29 September 2018

Costimulation requirements of induced murine systemic autoimmune disease

1 reference

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29 September 2018

Autoimmunity through cytokine-induced dendritic cell activation

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29 September 2018

Type-I interferon receptor deficiency reduces lupus-like disease in NZB mice

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29 September 2018

Interferon and granulopoiesis signatures in systemic lupus erythematosus blood

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29 September 2018

Resistance to xenobiotic-induced autoimmunity maps to chromosome 1.

1 reference

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29 September 2018

The in vitro proliferation of murine lymphocytes to mercuric chloride is restricted to mature T cells and is interleukin 1 dependent

1 reference

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29 September 2018

Xenobiotic acceleration of idiopathic systemic autoimmunity in lupus-prone bxsb mice

1 reference

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29 September 2018

Proteolytic cleavage of a self-antigen following xenobiotic-induced cell death produces a fragment with novel immunogenic properties

1 reference

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29 September 2018

Treatment of murine lupus with cDNA encoding IFN-gammaR/Fc

1 reference

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29 September 2018

Tissue levels of mercury determined in a deceased worker after occupational exposure

1 reference

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29 September 2018

Interleukin 6 dependence of anti-DNA antibody production: evidence for two pathways of autoantibody formation in pristane-induced lupus

1 reference

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29 September 2018

The prototypic Th2 autoimmunity induced by mercury is dependent on IFN-gamma and not Th1/Th2 imbalance.

1 reference

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29 September 2018

Roles of interferon-gamma and interleukin-4 in murine lupus

1 reference

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29 September 2018

Distinct regulatory roles of lymphocyte costimulatory pathways on T helper type-2 mediated autoimmune disease

1 reference

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29 September 2018

Murine susceptibility to mercury. II. autoantibody profiles and renal immune deposits in hybrid, backcross, and H-2d congenic mice

1 reference

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29 September 2018

Interleukin-6 receptor blockage ameliorates murine lupus nephritis.

1 reference

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29 September 2018

Autoimmunity and selected environmental factors of disease induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698107

29 September 2018

Interleukin 6 promotes murine lupus in NZB/NZW F1 mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698107

29 September 2018

Functional role of type I and type II interferons in antiviral defense

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698107

29 September 2018

Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698107

29 September 2018

In vivo treatment of (NZB X NZW)F1 lupus-like nephritis with monoclonal antibody to gamma interferon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698107

29 September 2018

Mercuric chloride-induced autoimmunity in the brown Norway rat. Cellular kinetics and major histocompatibility complex antigen expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698107

29 September 2018

Specificity and cross-reactive idiotypes of anti-glomerular basement membrane autoantibodies in HgCl2-induced autoimmune glomerulonephritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698107

29 September 2018

Mercuric chloride-treated brown Norway rats develop widespread tissue injury including necrotizing vasculitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5698107

29 September 2018

Molecular and cellular mechanisms of cardiotoxicity

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1700332

21 January 2018

Type I Interferon controls the onset and severity of autoimmune manifestations in lpr mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29055005

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type I IFN protects against murine lupus

1 reference

https://pubmed.ncbi.nlm.nih.gov/29055005

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/29055005

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Murine mercury-induced autoimmunity: the role of T-helper cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29055005

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Designing a type I interferon signaling phagosome

1 reference

https://pubmed.ncbi.nlm.nih.gov/29055005

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis and scleroderma share activation of a common type I interferon pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/29055005

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetics and pathogenicity of autoantibodies induced by mercuric chloride in the brown Norway rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/29055005

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyclonal effect of HgCl2 in the rat, its possible role in an experimental autoimmune disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29055005

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro effects of HgCl2 on murine lymphocytes. I. Preferable activation of CD4+ T cells in a responder strain

1 reference

https://pubmed.ncbi.nlm.nih.gov/29055005

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Skin-lightening creams are a possible exposure risk for systemic lupus erythematosus: comment on the article by Finckh et al

1 reference

https://pubmed.ncbi.nlm.nih.gov/29055005

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IFN-gamma is essential for the development of autoimmune glomerulonephritis in MRL/Ipr mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29055005

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IFN-alpha induces early lethal lupus in preautoimmune (New Zealand Black x New Zealand White) F1 but not in BALB/c mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29055005

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.1700332

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29055005%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29055005%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29055005%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

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