(Q47671871)

4 February 2018

title

Causal effects of cardiovascular risk factors on onset of major age-related diseases: A time-to-event Mendelian randomization study (English)

1 reference

4 February 2018

author

Alexander M Kulminski

1 reference

4 February 2018

author name string

Liang He

1 reference

4 February 2018

Irina Culminskaya

1 reference

4 February 2018

Yury Loika

1 reference

4 February 2018

Konstantin G Arbeev

1 reference

4 February 2018

Olivia Bagley

1 reference

4 February 2018

Matt Duan

1 reference

4 February 2018

Anatoliy I Yashin

1 reference

4 February 2018

publication date

27 September 2017

1 reference

4 February 2018

published in

Experimental Gerontology

1 reference

4 February 2018

Association of Body Mass Index With Cardiometabolic Disease in the UK Biobank: A Mendelian Randomization Study

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Modulation of Glucokinase Regulatory Protein: A Double-Edged Sword?

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Triglyceride-Increasing Alleles Associated with Protection against Type-2 Diabetes

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Glucokinase regulatory protein: complexity at the crossroads of triglyceride and glucose metabolism

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Genetic predisposition to increased blood cholesterol and triglyceride lipid levels and risk of Alzheimer disease: a Mendelian randomization analysis

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Assessing causality in the association between child adiposity and physical activity levels: a Mendelian randomization analysis

26 August 2018

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Mendelian randomization of blood lipids for coronary heart disease

26 August 2018

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Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis

26 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

Obesity and the obesity paradox in heart failure

26 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

LDL-cholesterol signaling induces breast cancer proliferation and invasion.

26 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

Mendelian randomization in health research: using appropriate genetic variants and avoiding biased estimates

26 August 2018

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Use of allele scores as instrumental variables for Mendelian randomization

26 August 2018

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26 August 2018

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26 August 2018

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26 August 2018

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Effect of long-term exposure to lower low-density lipoprotein cholesterol beginning early in life on the risk of coronary heart disease: a Mendelian randomization analysis

26 August 2018

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Body mass index, triglycerides, glucose, and blood pressure as predictors of type 2 diabetes in a middle-aged Norwegian cohort of men and women

26 August 2018

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26 August 2018

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26 August 2018

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Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

26 August 2018

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26 August 2018

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Obesity and type 2 diabetes: which patients are at risk?

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

Increased heart failure risk in normal-weight people with metabolic syndrome compared with metabolically healthy obese individuals

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

Adipocytokines and ischemic stroke: differential associations between stroke subtypes

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

Low-density lipoprotein cholesterol and the risk of cancer: a mendelian randomization study

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

Mendelian randomization studies do not support a role for raised circulating triglyceride levels influencing type 2 diabetes, glucose levels, or insulin resistance

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

Age trajectories of physiological indices in relation to healthy life course

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

Serum oxidized-LDL is associated with diabetes duration independent of maintaining optimized levels of LDL-cholesterol

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

26 August 2018

1 reference

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Genetics Analysis Workshop 16 Problem 2: the Framingham Heart Study data

26 August 2018

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Apolipoprotein e genotype, plasma cholesterol, and cancer: a Mendelian randomization study

26 August 2018

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Association between oxidized LDL, obesity and type 2 diabetes in a population-based cohort, the Health, Aging and Body Composition Study

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

Lipid modification in type 2 diabetes: the role of LDL and HDL.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

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26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

Leptinemia and its association with stroke and coronary heart disease in the Jackson Heart Study

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

Genetics of the Framingham Heart Study population

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

Lifelong reduction of LDL-cholesterol related to a common variant in the LDL-receptor gene decreases the risk of coronary artery disease--a Mendelian Randomisation study

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

Changes in triglyceride levels over time and risk of type 2 diabetes in young men.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

Body mass index and mortality in heart failure: A meta-analysis

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

Mendelian randomization as an instrumental variable approach to causal inference

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

SH2B1 enhances leptin signaling by both Janus kinase 2 Tyr813 phosphorylation-dependent and -independent mechanisms

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

The SH2B gene is associated with serum leptin and body fat in normal female twins.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

SH2B1 (SH2-B) and JAK2: a multifunctional adaptor protein and kinase made for each other

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

High leptin levels are associated with stroke

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

Multi-Ethnic Study of Atherosclerosis: objectives and design

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

Obesity and the risk of heart failure

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

Trends in causes of death among the elderly

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

Hypertriglyceridemic hyperapob: the unappreciated atherogenic dyslipoproteinemia in type 2 diabetes mellitus

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

Left-truncated data with age as time scale: an alternative for survival analysis in the elderly population

26 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

Design of the Women's Health Initiative clinical trial and observational study. The Women's Health Initiative Study Group

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

Short-term control of glucokinase activity: role of a regulatory protein

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

The Atherosclerosis Risk in Communities (ARIC) Study: design and objectives. The ARIC investigators

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

The Atherosclerosis Risk in Communities (ARIC) Study. Introduction and objectives of the hemostasis component

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

The Third Generation Cohort of the National Heart, Lung, and Blood Institute's Framingham Heart Study: Design, Recruitment, and Initial Examination

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5874182

Predictors of congestive heart failure in the elderly: the Cardiovascular Health Study

1 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28964830

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Body fat distribution and risk of type 2 diabetes in the general population: are there differences between men and women? The MONICA/KORA Augsburg cohort study

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28964830

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.EXGER.2017.09.019

1 reference

4 February 2018

PMC publication ID

5874182

0 references

1 reference

4 February 2018