(Q47132424)

8 January 2018

title

Molecular Mechanisms of Synaptic Vesicle Priming by Munc13 and Munc18. (English)

1 reference

8 January 2018

1 reference

8 January 2018

Nils Brose

object named as

Nils Brose

1 reference

8 January 2018

author name string

Ying Lai

1 reference

8 January 2018

Ucheor B Choi

1 reference

8 January 2018

Jeremy Leitz

1 reference

8 January 2018

Hong Jun Rhee

1 reference

8 January 2018

Choongku Lee

1 reference

8 January 2018

Bekir Altas

1 reference

8 January 2018

Minglei Zhao

1 reference

8 January 2018

Richard A Pfuetzner

1 reference

8 January 2018

Austin L Wang

1 reference

8 January 2018

JeongSeop Rhee

1 reference

8 January 2018

language of work or name

English

0 references

publication date

1 August 2017

1 reference

8 January 2018

published in

Neuron

1 reference

8 January 2018

volume

1 reference

8 January 2018

issue

1 reference

8 January 2018

page(s)

591-607.e10

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8 January 2018

Morphologies of synaptic protein membrane fusion interfaces

cites work

1 reference

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Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN.

23 May 2018

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Fusion Competent Synaptic Vesicles Persist upon Active Zone Disruption and Loss of Vesicle Docking

23 May 2018

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N-terminal domain of complexin independently activates calcium-triggered fusion

23 May 2018

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Complexin induces a conformational change at the membrane-proximal C-terminal end of the SNARE complex

23 May 2018

1 reference

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Functional synergy between the Munc13 C-terminal C1 and C2 domains

23 May 2018

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Should I stop or should I go? The role of complexin in neurotransmitter release.

23 May 2018

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A direct role for the Sec1/Munc18-family protein Vps33 as a template for SNARE assembly

23 May 2018

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Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosis

23 May 2018

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Complexins: small but capable

23 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Syntaxin opening by the MUN domain underlies the function of Munc13 in synaptic-vesicle priming

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Towards reconstitution of membrane fusion mediated by SNAREs and other synaptic proteins

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

The morphological and molecular nature of synaptic vesicle priming at presynaptic active zones

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

A distinct tethering step is vital for vacuole membrane fusion

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Complexin inhibits spontaneous release and synchronizes Ca2+-triggered synaptic vesicle fusion by distinct mechanisms

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Neurotransmitter release: the last millisecond in the life of a synaptic vesicle

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Reconstitution of the vital functions of Munc18 and Munc13 in neurotransmitter release

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Studying calcium-triggered vesicle fusion in a single vesicle-vesicle content and lipid-mixing system

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Nonconserved Ca(2+)/calmodulin binding sites in Munc13s differentially control synaptic short-term plasticity

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Immobilization of proteins for single-molecule fluorescence resonance energy transfer measurements of conformation and dynamics

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

The presynaptic active zone

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Munc13-4 reconstitutes calcium-dependent SNARE-mediated membrane fusion

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Munc13 mediates the transition from the closed syntaxin–Munc18 complex to the SNARE complex

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Optimizing Methods to Recover Absolute FRET Efficiency from Immobilized Single Molecules

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

A conserved membrane attachment site in alpha-SNAP facilitates N-ethylmaleimide-sensitive factor (NSF)-driven SNARE complex disassembly.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Munc13-2 differentially affects hippocampal synaptic transmission and plasticity

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Synaptotagmin-1 functions as a Ca2+ sensor for spontaneous release

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

NMR analysis of the closed conformation of syntaxin-1.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Accessory proteins stabilize the acceptor complex for synaptobrevin, the 1:1 syntaxin/SNAP-25 complex

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Binding of the Munc13-1 MUN domain to membrane-anchored SNARE complexes

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

CAPS-1 and CAPS-2 are essential synaptic vesicle priming proteins.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Open syntaxin docks synaptic vesicles

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Structure and function of SNARE and SNARE-interacting proteins

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Single-molecule studies of SNARE complex assembly reveal parallel and antiparallel configurations

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Differential control of vesicle priming and short-term plasticity by Munc13 isoforms

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Beta phorbol ester- and diacylglycerol-induced augmentation of transmitter release is mediated by Munc13s and not by PKCs

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

An open form of syntaxin bypasses the requirement for UNC-13 in vesicle priming

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Synaptotagmin I functions as a calcium regulator of release probability

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

The t-SNARE syntaxin is sufficient for spontaneous fusion of synaptic vesicles to planar membranes

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Definition of Munc13-homology-domains and characterization of a novel ubiquitously expressed Munc13 isoform

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Three-dimensional structure of the neuronal-Sec1-syntaxin 1a complex

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Synaptic assembly of the brain in the absence of neurotransmitter secretion

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

nSec1 binds a closed conformation of syntaxin1A.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Drosophila UNC-13 is essential for synaptic transmission

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

A conformational switch in syntaxin during exocytosis: role of munc18.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

SNAREpins: minimal machinery for membrane fusion

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Specificity and regulation of a synaptic vesicle docking complex

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Synaptotagmin I: a major Ca2+ sensor for transmitter release at a central synapse

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Calcium dependence of the rate of exocytosis in a synaptic terminal

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Complexins: cytosolic proteins that regulate SNAP receptor function

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Lipid composition of different areas of murine brain: effects of lipid extraction procedures

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

The primed SNARE-complexin-synaptotagmin complex for neuronal exocytosis

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Conformational change of syntaxin linker region induced by Munc13s initiates SNARE complex formation in synaptic exocytosis.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

The principle of membrane fusion in the cell (Nobel lecture).

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Identification of the minimal protein domain required for priming activity of Munc13-1.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

A minimal domain responsible for Munc13 activity

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Arachidonic acid allows SNARE complex formation in the presence of Munc18.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

A transient N-terminal interaction of SNAP-25 and syntaxin nucleates SNARE assembly

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Sequential SNARE assembly underlies priming and triggering of exocytosis.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

UNC-13 is required for synaptic vesicle fusion in C. elegans

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

An efficient method for infection of adrenal chromaffin cells using the Semliki Forest virus gene expression system

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Calmodulin and Munc13 Form a Ca2+ Sensor/Effector Complex that Controls Short-Term Synaptic Plasticity

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5747255

Intracellular calcium dependence of transmitter release rates at a fast central synapse

1 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28772123

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Analysis of neurotransmitter release mechanisms by photolysis of caged Ca²⁺ in an autaptic neuron culture system

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28772123

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.NEURON.2017.07.004

1 reference

8 January 2018

PMC publication ID

5747255

1 reference

8 January 2018

PubMed publication ID

28772123

1 reference

8 January 2018