(Q47194413)

19 July 2018

title

The atypical antipsychotic olanzapine causes weight gain by targeting serotonin receptor 2C. (English)

1 reference

19 July 2018

1 reference

Caleb C Lord

1 reference

19 July 2018

Steven C Wyler

1 reference

19 July 2018

Rong Wan

1 reference

19 July 2018

Carlos M Castorena

1 reference

19 July 2018

Newaz Ahmed

1 reference

19 July 2018

Dias Mathew

1 reference

19 July 2018

Syann Lee

1 reference

19 July 2018

Chen Liu

1 reference

19 July 2018

Joel K Elmquist

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19 July 2018

language of work or name

English

0 references

publication date

14 August 2017

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19 July 2018

Journal of Clinical Investigation

published in

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19 July 2018

volume

127

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19 July 2018

issue

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19 July 2018

page(s)

3402-3406

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19 July 2018

Metabolic syndrome and obesity among users of second generation antipsychotics: A global challenge for modern psychopharmacology.

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5669575

Pharmacogenetics of antipsychotic-induced weight gain: review and clinical implications.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5669575

In vivo actions of atypical antipsychotic drug on serotonergic and dopaminergic systems

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5669575

Antipsychotic medications: metabolic and cardiovascular risk

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5669575

A comparison of ten-year cardiac risk estimates in schizophrenia patients from the CATIE study and matched controls

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5669575

H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5669575

Antipsychotics in the treatment of mood disorders and risk of tardive dyskinesia

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5669575

Antagonism by olanzapine of dopamine D1, serotonin2, muscarinic, histamine H1 and alpha 1-adrenergic receptors in vitro

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5669575

Eating disorder and epilepsy in mice lacking 5-HT2c serotonin receptors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5669575

Melanin-concentrating hormone is necessary for olanzapine-inhibited locomotor activity in male mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5669575

The antipsychotic olanzapine interacts with the gut microbiome to cause weight gain in mouse

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5669575

Lorcaserin and pimavanserin: emerging selectivity of serotonin receptor subtype-targeted drugs

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5669575

Serotonin 2C receptors in pro-opiomelanocortin neurons regulate energy and glucose homeostasis

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5669575

Actigraphic monitoring of activity and rest in schizophrenic patients treated with olanzapine or risperidone.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5669575

Olanzapine-induced weight gain in the rat: role of 5-HT2C and histamine H1 receptors.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5669575

Rosiglitazone in the assistance of metabolic control during olanzapine administration in schizophrenia: a pilot double-blind, placebo-controlled, 12-week trial

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5669575

5-HT2CRs expressed by pro-opiomelanocortin neurons regulate energy homeostasis

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5669575

Clozapine and olanzapine are associated with food craving and binge eating: results from a randomized double-blind study

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5669575

From the Cover: Antipsychotic drug-induced weight gain mediated by histamine H1 receptor-linked activation of hypothalamic AMP-kinase

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5669575

Effects of olanzapine in male rats: enhanced adiposity in the absence of hyperphagia, weight gain or metabolic abnormalities.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5669575

Weight gain associated with the -759C/T polymorphism of the 5HT2C receptor and olanzapine

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5669575

Nizatidine for prevention of weight gain with olanzapine: a double-blind placebo-controlled trial

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5669575

Radioreceptor binding profile of the atypical antipsychotic olanzapine

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5669575

14 August 2018

Identifiers

DOI

10.1172/JCI93362

1 reference

19 July 2018

PMC publication ID

5669575

1 reference

19 July 2018

PubMed publication ID

28805659

1 reference

19 July 2018