(Q46361020)

21 December 2017

title

Accumulation of HtrA2/Omi in neuronal and glial inclusions in brains with alpha-synucleinopathies (English)

1 reference

21 December 2017

1 reference

21 December 2017

Herbert Budka

0 references

Yasuhiro Kawamoto

1 reference

21 December 2017

Yoshito Kobayashi

1 reference

21 December 2017

Yasuyuki Suzuki

1 reference

21 December 2017

Haruhisa Inoue

1 reference

21 December 2017

Hidekazu Tomimoto

1 reference

21 December 2017

Ichiro Akiguchi

1 reference

21 December 2017

L Miguel Martins

1 reference

21 December 2017

Ryosuke Takahashi

1 reference

21 December 2017

publication date

1 October 2008

1 reference

21 December 2017

Journal of Neuropathology & Experimental Neurology

published in

1 reference

21 December 2017

volume

1 reference

21 December 2017

issue

1 reference

21 December 2017

page(s)

984-993

1 reference

21 December 2017

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

cites work

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

alpha-Synuclein locus triplication causes Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

Alpha-synuclein locus duplication as a cause of familial Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

Ultrastructure of Lewy bodies in the stellate ganglion

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

The cellular pathology of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

α-Synuclein in Lewy bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

NACP, a presynaptic protein, immunoreactivity in Lewy bodies in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

Accumulation of alpha-synuclein/NACP is a cytopathological feature common to Lewy body disease and multiple system atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

Orthostatic hypotension and nicotine sensitivity in a case of multiple system atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

Glial cytoplasmic inclusions in the CNS of patients with multiple system atrophy (striatonigral degeneration, olivopontocerebellar atrophy and Shy-Drager syndrome).

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

Multiple-system atrophy: a new alpha-synuclein disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

Alpha-synuclein immunoreactivity in glial cytoplasmic inclusions in multiple system atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

X-linked IAP is a direct inhibitor of cell-death proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

A single BIR domain of XIAP sufficient for inhibiting caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

IAP family proteins--suppressors of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

Inhibitor of apoptosis proteins are substrates for the mitochondrial serine protease Omi/HtrA2

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

Omi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

Mitochondrial protease Omi/HtrA2 enhances caspase activation through multiple pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

Relationships between Lewy bodies and pale bodies in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

PINK1 protein in normal human brain and Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

PINK1, a gene product of PARK6, accumulates in alpha-synucleinopathy brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

Cell death mechanisms in multiple system atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotective

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

Proteasome mediates dopaminergic neuronal degeneration, and its inhibition causes alpha-synuclein inclusions

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

The distribution of oligodendroglial inclusions in multiple system atrophy and its relevance to clinical symptomatology

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

Alzheimer's disease-associated amyloid beta interacts with the human serine protease HtrA2/Omi

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

Beta-amyloid precursor protein is a direct cleavage target of HtrA2 serine protease. Implications for the physiological function of HtrA2 in the mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

HtrA2 regulates beta-amyloid precursor protein (APP) metabolism through endoplasmic reticulum-associated degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31818809F4

10.1097/NEN.0B013E31818809F4

21 January 2018

Identifiers

DOI

1 reference

21 December 2017

1 reference

21 December 2017