(Q46341082)

21 December 2017

title

Local lymph node assay (LLNA): comparison of different protocols by testing skin-sensitizing epoxy resin system components (English)

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21 December 2017

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Armin O Gamer

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21 December 2017

Eberhard Nies

series ordinal

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21 December 2017

Hans-Werner Vohr

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21 December 2017

language of work or name

English

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publication date

13 September 2008

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21 December 2017

Regulatory Toxicology and Pharmacology

published in

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21 December 2017

volume

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21 December 2017

issue

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21 December 2017

page(s)

290-298

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21 December 2017

The performance of the local lymph node assay with chemicals identified as contact allergens in the human maximization test

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An attempt to improve diagnostics of contact allergy due to epoxy resin systems. First results of the multicentre study EPOX 2002.

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Examination of the local lymph node assay for use in contact sensitization risk assessment

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Use of a B cell marker (B220) to discriminate between allergens and irritants in the local lymph node assay

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A murine local lymph node assay for the identification of contact allergens. Assay development and results of an initial validation study

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Classification of contact allergens according to potency: proposals

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Comparison of the skin sensitizing potential of unsaturated compounds as assessed by the murine local lymph node assay (LLNA) and the guinea pig maximization test (GPMT).

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Further evaluation of the local lymph node assay in the final phase of an international collaborative trial

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A modified murine local lymph node assay for the differentiation of contact photoallergy from phototoxicity by analysis of cytokine expression in skin-draining lymph node cells

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Intralaboratory validation of alternative endpoints in the murine local lymph node assay for the identification of contact allergic potential: primary ear skin irritation and ear-draining lymph node hyperplasia induced by topical chemicals

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Skin sensitization in chemical risk assessment: report of a WHO/IPCS international workshop focusing on dose-response assessment

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A quantitative method for assessing the sensitizing potency of low molecular weight chemicals using a local lymph node assay: employment of a regression method that includes determination of the uncertainty margins.

7 January 2021

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An intra-laboratory validation of the Integrated Model for the Differentiation of Skin Reactions (IMDS): discrimination between (photo)allergic and (photo)irritant skin reactions in mice

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Influence of application vehicle on skin sensitization to methylchloroisothiazolinone/methylisothiazolinone: an analysis using the local lymph node assay.

7 January 2021

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Quantitative comparison of the results obtained by the multiple-dose guinea pig maximization test and the non-radioactive murine local lymph-node assay for various biocides

7 January 2021

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7 January 2021

Identifiers

DOI

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21 December 2017

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21 December 2017