(Q46110468)

19 December 2017

title

Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase (English)

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19 December 2017

author name string

Monia BP

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19 December 2017

Johnston JF

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19 December 2017

Geiger T

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19 December 2017

Muller M

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19 December 2017

Fabbro D

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19 December 2017

language of work or name

English

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publication date

1 June 1996

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19 December 2017

published in

Nature Medicine

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19 December 2017

volume

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19 December 2017

issue

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19 December 2017

page(s)

668-675

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19 December 2017

The ins and outs of Raf kinases

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNM0696-668

The MAP kinase cascade is essential for diverse signal transduction pathways

21 January 2018

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Mammalian Ras interacts directly with the serine/threonine kinase Raf

21 January 2018

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https://api.crossref.org/works/10.1038%2FNM0696-668

Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1

21 January 2018

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https://api.crossref.org/works/10.1038%2FNM0696-668

Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro

21 January 2018

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The ras gene family and human carcinogenesis

21 January 2018

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Mutational activation of c-raf-1 and definition of the minimal transforming sequence

21 January 2018

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Activation of human raf transforming genes by deletion of normal amino-terminal coding sequences

21 January 2018

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Critical Tyrosine Residues Regulate the Enzymatic and Biological Activity of Raf-1 Kinase

21 January 2018

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Isolation of a transforming sequence from a human bladder carcinoma cell line

21 January 2018

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Oligonucleotide sequences required for natural killer cell activation

21 January 2018

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https://api.crossref.org/works/10.1038%2FNM0696-668

Lipofection of synthetic oligodeoxyribonucleotide having a palindromic sequence of AACGTT to murine splenocytes enhances interferon production and natural killer activity

21 January 2018

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Diversity in function and regulation of MAP kinase pathways

21 January 2018

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A single amino acid change in Raf-1 inhibits Ras binding and alters Raf-1 function

21 January 2018

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7 January 2021

Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus

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7 January 2021

Molecular cloning of an activated human oncogene, homologous to v-raf, from primary stomach cancer

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7 January 2021

Detection of a raf-related and two other transforming DNA sequences in human tumors maintained in nude mice

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7 January 2021

The state of the art in antisense research

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7 January 2021

Does antisense exist?

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https://api.crossref.org/works/10.1038%2FNM0696-668

7 January 2021

Therapeutic Applications of Oligonucleotides

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https://api.crossref.org/works/10.1038%2FNM0696-668

7 January 2021

Effects of phosphorothioate capping on antisense oligonucleotide stability, hybridization and antiviral efficacy versus herpes simplex virus infection

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https://api.crossref.org/works/10.1038%2FNM0696-668

7 January 2021

Breast tumor cell lines from pleural effusions

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https://api.crossref.org/works/10.1038%2FNM0696-668

7 January 2021

Inhibition of protein kinase C-alpha expression in mice after systemic administration of phosphorothioate antisense oligodeoxynucleotides

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https://api.crossref.org/works/10.1038%2FNM0696-668

7 January 2021

Heterologous protection against influenza by injection of DNA encoding a viral protein

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https://api.crossref.org/works/10.1038%2FNM0696-668

7 January 2021

Complementary oligonucleotide binding to transfer RNA

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https://api.crossref.org/works/10.1038%2FNM0696-668

7 January 2021

Binding of complementary oligoribonucleotides to yeast initiator transfer RNA

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https://api.crossref.org/works/10.1038%2FNM0696-668

7 January 2021

Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 2. Kinetic description of the reaction of an RNA substrate that forms a mismatch at the active site

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https://api.crossref.org/works/10.1038%2FNM0696-668

7 January 2021

Implication of RNA structure on antisense oligonucleotide hybridization kinetics

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https://api.crossref.org/works/10.1038%2FNM0696-668

7 January 2021

DNA from bacteria, but not from vertebrates, induces interferons, activates natural killer cells and inhibits tumor growth

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https://api.crossref.org/works/10.1038%2FNM0696-668

7 January 2021

Nucleotide sequence analysis of the T24 human bladder carcinoma oncogene

1 reference

https://api.crossref.org/works/10.1038%2FNM0696-668

7 January 2021

Four human carcinoma cell lines with novel mutations in position 12 of c-K-ras oncogene

1 reference

https://api.crossref.org/works/10.1038%2FNM0696-668

7 January 2021

A derivative of staurosporine (CGP 41 251) shows selectivity for protein kinase C inhibition and in vitro anti-proliferative as well as in vivo anti-tumor activity

1 reference

https://api.crossref.org/works/10.1038%2FNM0696-668

7 January 2021

Inhibition of cellular ras prevents smooth muscle cell proliferation after vascular injury in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNM0696-668

7 January 2021

Identifiers

DOI

10.1038/NM0696-668

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19 December 2017

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19 December 2017